Patents by Inventor John Vederas

John Vederas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • APELIN PEPTIDES AND USES THEREOF
    Publication number: 20200239537
    Abstract: The disclosure relates to modified apelin polypeptides having increased stability against kallikrein, NEP and ACE2 degradation and/or potency relative to the native apelin-13 and apelin-17 polypeptides. Embodiments also disclose methods of using the polypeptides for treating cardiovascular disorders.
    Type: Application
    Filed: March 16, 2020
    Publication date: July 30, 2020
    Inventors: Gavin OUDIT, John VEDERAS, Shaun MCKINNIE, Conrad FISCHER
  • Apelin peptides and uses thereof
    Patent number: 10723776
    Abstract: The disclosure relates to modified apelin polypeptides having increased stability against kallikrein, NEP and ACE2 degradation and/or potency relative to the native apelin-13 and apelin-17 polypeptides. Embodiments also disclose methods of using the polypeptides for treating cardiovascular disorders.
    Type: Grant
    Filed: March 16, 2020
    Date of Patent: July 28, 2020
    Assignee: THE GOVERNERS OF THE UNIVERSITY OF ALBERTA
    Inventors: Gavin Oudit, John Vederas, Shaun McKinnie, Conrad Fischer
  • Apelin peptides and uses thereof
    Patent number: 10640545
    Abstract: The disclosure relates to modified apelin polypeptides having increased stability against kallikrein, NEP and ACE2 degradation and/or potency relative to the native apelin-13 and apelin-17 polypeptides. Embodiments also disclose methods of using the polypeptides for treating cardiovascular disorders.
    Type: Grant
    Filed: July 3, 2018
    Date of Patent: May 5, 2020
    Assignee: THE GOVERNORS OF THE UNIV OF ALBERTA TEC EDMONTON
    Inventors: Gavin Oudit, John Vederas, Shaun McKinnie, Conrad Fischer
  • APELIN PEPTIDES AND USES THEREOF
    Publication number: 20190010202
    Abstract: The disclosure relates to modified apelin polypeptides having increased stability against kallikrein, NEP and ACE2 degradation and/or potency relative to the native apelin-13 and apelin-17 polypeptides. Embodiments also disclose methods of using the polypeptides for treating cardiovascular disorders.
    Type: Application
    Filed: July 3, 2018
    Publication date: January 10, 2019
    Inventors: Gavin OUDIT, John VEDERAS, Shaun MCKINNIE, Conrad FISCHER
  • Compounds that stimulate glucose utilization and methods of use
    Publication number: 20060205811
    Abstract: The invention provides novel compounds of the Formula (I) that stimulate rates of glucose oxidation in myocardial cells: wherein W, Cyc, p, Y, X, Z, R, R1, R2, R3, R4, i and n are as defined for Formula (I) herein. The invention also relates to pharmaceutical compositions comprising compounds capable of stimulation of glucose oxidation, methods for increasing glucose oxidation rates in myocardial cells, and methods of treatment of myocardial ischemia.
    Type: Application
    Filed: May 18, 2006
    Publication date: September 14, 2006
    Applicant: THE GOVERNORS OF THE UNIVERSITY OF ALBERTA
    Inventors: Gary Lopaschuk, John Vederas, Jason Dyck
  • Compounds that stimulate glucose utilization and methods of use
    Publication number: 20060173208
    Abstract: The invention provides novel compounds of the Formula (I) that stimulate rates of glucose oxidation in myocardial cells: wherein W, Cyc, p, Y, X, Z, R, R1, R2, R3, R4, i and n are as defined for Formula (I) herein. The invention also relates to pharmaceutical compositions comprising compounds capable of stimulation of glucose oxidation, methods for increasing glucose oxidation rates in myocardial cells, and methods of treatment of myocardial ischemia.
    Type: Application
    Filed: March 6, 2006
    Publication date: August 3, 2006
    Applicant: The Governors of the University of Alberta
    Inventors: Gary Lopaschuk, John Vederas, Jason Dyck
  • Compounds that stimulate glucose utilization and methods of use
    Publication number: 20050182133
    Abstract: The invention provides novel compounds of the Formula (I) that stimulate rates of glucose oxidation in myocardial cells: wherein W, Cyc, p, Y, X, Z, R, R1, R2, R3, R4, I, m and n are as defined for Formula (I) herein. The invention also relates to pharmaceutical compositions comprising compounds capable of stimulation of glucose oxidation, methods for increasing glucose oxidation rates in myocardial cells, and methods of treatment of myocardial ischemia.
    Type: Application
    Filed: February 23, 2005
    Publication date: August 18, 2005
    Applicant: University of Alberta
    Inventors: Gary Lopaschuk, John Vederas, Jason Dyck