Patents by Inventor John W. Fenton, II

John W. Fenton, II has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for coating invasive devices with inhibitors of thrombin
    Patent number: 5691311
    Abstract: This invention relates to novel biologically active molecules which bind to and inhibit thrombin. Specifically, these molecules are characterized by a thrombin anion-binding exosite association moiety (ABEAM); a linker portion of at least 18 .ANG. in length; and a thrombin catalytic site-directed moiety (CSDM). This invention also relates to compositions, combinations and methods which employ these molecules for therapeutic, prophylactic and diagnostic purposes.
    Type: Grant
    Filed: May 11, 1995
    Date of Patent: November 25, 1997
    Assignee: Biogen, Inc.
    Inventors: John M. Maraganore, John W. Fenton, II, Toni Kline
  • Inhibitors of thrombin
    Patent number: 5433940
    Abstract: This invention relates to novel biologically active molecules which bind to and inhibit thrombin. Specifically, these molecules are characterized by a thrombin anion-binding exosite association moiety (ABEAM); a linker portion of at least 18.ANG. in length; and a thrombin catalytic site-directed moiety (CSDM). This invention also relates to compositions, combinations and methods which employ these molecules for therapeutic, prophylactic and diagnostic purposes.
    Type: Grant
    Filed: February 10, 1992
    Date of Patent: July 18, 1995
    Assignee: Biogen, Inc.
    Inventors: John M. Maraganore, John W. Fenton, II, Toni Kline
  • Inhibitors of thrombin
    Patent number: 5196404
    Abstract: This invention relates to novel biologically active molecules which bind to and inhibit thrombin. Specifically, these molecules are characterized by a thrombin anion-binding exosite association moiety (ABEAM); a linker portion of at least 18 .ANG. in length; and a thrombin catalytic site-directed moiety (CSDM). This invention also relates to compositions, combinations and methods which employ these molecules for therapeutic, prophylactic and diagnostic purposes.
    Type: Grant
    Filed: July 6, 1990
    Date of Patent: March 23, 1993
    Assignees: Biogen, Inc., Health Research, Inc.
    Inventors: John M. Maraganore, John W. Fenton, II, Toni Kline