Patents by Inventor John W. Hanifin, Jr.

John W. Hanifin, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted phenyl-1,2,4-triazolo[2,3-b]pyridazin-3(2H)ones as anti-asthma agents
    Patent number: 4515791
    Abstract: Substituted phenyl-1,2,4-triazolo[4,3-b]pyridazin-3(2H)-ones, useful as anti-asthma agents.
    Type: Grant
    Filed: June 15, 1981
    Date of Patent: May 7, 1985
    Assignee: American Cyanamid Company
    Inventors: George R. Allen, Jr., John W. Hanifin, Jr., Daniel B. Moran, Jay D. Albright
  • Method of treating asthma
    Patent number: 4293554
    Abstract: A method of treating asthma in a warm-blooded animal using the compound 6-phenyl-1,2,4-triazolo[4,3-b]pyridazin-3(2H)-one.
    Type: Grant
    Filed: February 21, 1980
    Date of Patent: October 6, 1981
    Assignee: American Cyanamid Company
    Inventors: George R. Allen, Jr., John W. Hanifin, Jr., Daniel B. Moran, Jay D. Albright
  • Substituted phenyl esters of isoxazolecarboxylic acids
    Patent number: 4284785
    Abstract: Isoxazolecarboxylic acid phenyl esters which are intermediates for the preparation of anti-inflammatory agents.
    Type: Grant
    Filed: December 19, 1979
    Date of Patent: August 18, 1981
    Assignee: American Cyanamid Company
    Inventors: John W. Hanifin, Jr., David N. Ridge
  • 2-Benzoyl-3-dimethylamino-2-alkenonitriles
    Patent number: 4259256
    Abstract: This disclosure describes novel substituted 2-benzoyl-3-alkoxy-2-alkenonitriles and substituted 2-benzoyl-3-amino-2-alkenonitriles which are useful as intermediates for the preparation of certain substituted cis-2-benzoyl-3-hydroxy-2-alkenonitriles which possess anti-inflammatory activity.
    Type: Grant
    Filed: July 2, 1979
    Date of Patent: March 31, 1981
    Assignee: American Cyanamid Company
    Inventors: John W. Hanifin, Jr., David N. Ridge
  • Substituted phenyl-2-cyano-2-thioalkenoic acid esters
    Patent number: 4254047
    Abstract: Substituted phenyl-2-cyano-2-thioalkenoic acid esters which are useful as anti-inflammatory agents and as inhibitors of the progressive joint deterioration characteristic of arthritic disease.
    Type: Grant
    Filed: December 17, 1979
    Date of Patent: March 3, 1981
    Assignee: American Cyanamid Company
    Inventors: John W. Hanifin, Jr., David N. Ridge
  • Substituted phenyl-2-cyano-2-alkenoic acid esters
    Patent number: 4254049
    Abstract: Substituted phenyl-2-cyano-2-alkenoic acid esters which are useful as anti-inflammatory agents and as inhibitors of the progressive joint deterioration characteristic of arthritic disease.
    Type: Grant
    Filed: December 17, 1979
    Date of Patent: March 3, 1981
    Assignee: American Cyanamid Company
    Inventors: John W. Hanifin, Jr., David N. Ridge
  • Substituted phenyl alkylidene acetoacetonitriles
    Patent number: 4254048
    Abstract: Substituted-phenyl alkylidene acetoacetonitriles which are useful as anti-inflammatory agents and as inhibitors of the progressive joint deterioration characteristic of arthritic disease.
    Type: Grant
    Filed: December 17, 1979
    Date of Patent: March 3, 1981
    Assignee: American Cyanamid Company
    Inventors: John W. Hanifin, Jr., David N. Ridge
  • 6-Phenyl-1,2,4-triazolo[4,3-b]pyridazines and their uses in treating anxiety
    Patent number: 4230705
    Abstract: This disclosure describes novel substituted 6-phenyl-1,2,4-triazolo[4,3-b]pyridazines useful as anxiolytic agents.
    Type: Grant
    Filed: September 22, 1976
    Date of Patent: October 28, 1980
    Assignee: American Cyanamid Company
    Inventors: George R. Allen, Jr., John W. Hanifin, Jr., Daniel B. Moran, Jay D. Albright
  • Alkali metal and alkaline earth metal salts of benzoylacetonitriles
    Patent number: 4197312
    Abstract: This disclosure describes new compounds and compositions of matter useful as anti-inflammatory agents and as inhibitors of the progressive joint deterioration characteristic of arthritic disease and the methods of meliorating inflammation and of inhibiting joint deterioration in mammals therewith, the novel active ingredients of said compositions of matter being the pharmacologically acceptable cationic salts of benzoylacetonitrile, o-fluorobenzoylacetonitrile, m-fluorobenzoylacetonitrile, p-fluorobenzoylacetonitrile, or mixtures thereof.
    Type: Grant
    Filed: May 9, 1978
    Date of Patent: April 8, 1980
    Assignee: American Cyanamid Company
    Inventors: Adolph E. Sloboda, John W. Hanifin, Jr.
  • Thiophenepropionitriles
    Patent number: 4197310
    Abstract: This disclosure describes new compounds and compositions of matter useful as anti-inflammatory agents and as inhibitors of the progressive joint deterioration characteristic of arthritic disease and the methods of meliorating inflammation and of inhibiting joint deterioration in mammals therewith, the novel active ingredients of said compositions of matter being certain substituted cis-2-[2(or 3)-thenoyl]-3-hydroxy-2-alkenenitriles and/or the pharmacologically acceptable cationic salts thereof.
    Type: Grant
    Filed: April 30, 1979
    Date of Patent: April 8, 1980
    Assignee: American Cyanamid Company
    Inventors: John W. Hanifin, Jr., David N. Ridge
  • 2-Benzoyl-3-alkoxy-2-alkenonitriles
    Patent number: 4181677
    Abstract: This disclosure describes novel substituted 2-benzoyl-3-alkoxy-2-alkenonitriles and substituted 2-benzoyl-3-amino-2-alkenonitriles which are useful as intermediates for the preparation of certain substituted cis-2-benzoyl-3-hydroxy-2-alkenonitriles which possess anti-inflammatory activity.
    Type: Grant
    Filed: December 13, 1978
    Date of Patent: January 1, 1980
    Assignee: American Cyanamid Company
    Inventors: John W. Hanifin, Jr., David N. Ridge
  • Cis-2-benzoyl-3-hydroxy-2-alkenonitriles as anti-inflammatory agents
    Patent number: 4173650
    Abstract: This disclosure describes new compounds and compositions of matter useful as anti-inflammatory agents and as inhibitors of the progressive joint deterioration characteristic of arthritic disease and the methods of meliorating inflammation and of inhibiting joint deterioration in mammals therewith, the novel active ingredients of said compositions of matter being certain substituted cis-2-benozyl-3-hydroxy-2-alkenonitriles and/or the pharmacologically acceptable cationic salts thereof.
    Type: Grant
    Filed: November 3, 1978
    Date of Patent: November 6, 1979
    Assignee: American Cyanamid Company
    Inventors: John W. Hanifin, Jr., David N. Ridge
  • Compositions containing cis-2-benzoyl-3-hydroxy-crotononitrile used to treat inflammation and joint deterioration
    Patent number: 4170656
    Abstract: This disclosure describes compositions of matter useful as anti-inflammatory agents and as inhibitors of the progressive joint deterioration characteristic of arthritic disease, and the methods of meliorating inflammation and of inhibiting joint deterioration in mammals therewith, the active ingredients of said composition of matter being certain cis-2-benzoyl-3-hydroxy-2-alkenonitriles and/or the pharmacologically acceptable cationic salts thereof.
    Type: Grant
    Filed: March 31, 1978
    Date of Patent: October 9, 1979
    Assignee: American Cyanamid Company
    Inventors: John W. Hanifin, Jr., David N. Ridge
  • Method for antagonizing aldosteronic action and inducing diuresis by administering a tetrasubstituted imidazolidine
    Patent number: 4110445
    Abstract: Novel 1-(phenyl or p-chlorophenyl)-2,4-disubstituted-3-methylimidazolidines and a method for inducing diuresis and treating hyperaldosteronism by the administration thereof.
    Type: Grant
    Filed: April 20, 1977
    Date of Patent: August 29, 1978
    Assignee: American Cyanamid Company
    Inventors: John W. Hanifin, Jr., Robert Z. Gussin, Elliott Cohen