Patents by Inventor John W. Howell, Jr.

John W. Howell, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11779680
    Abstract: The present invention is directed to a composition comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. Also disclosed is a tissue graft or implant comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. The composition and/or tissue graft or implant of the invention is usable in combination with seeded cells, a tissue growth factor, and/or a chemotactic gent to attract a desired cell.
    Type: Grant
    Filed: October 26, 2020
    Date of Patent: October 10, 2023
    Assignee: RTI Surgical, Inc.
    Inventors: C. Randal Mills, John R. Bianchi, Michael R. Roberts, David T. Cheung, Chandrasekaran Nataraj, John W. Howell, Jr.
  • Publication number: 20210046215
    Abstract: The present invention is directed to a composition comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. Also disclosed is a tissue graft or implant comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. The composition and/or tissue graft or implant of the invention is usable in combination with seeded cells, a tissue growth factor, and/or a chemotactic gent to attract a desired cell.
    Type: Application
    Filed: October 26, 2020
    Publication date: February 18, 2021
    Inventors: C. Randal Mills, John R. Bianchi, Michael R. Roberts, David T. Cheung, Chandrasekaran Nataraj, John W. Howell, JR.
  • Patent number: 10814034
    Abstract: The present invention is directed to a composition comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. Also disclosed is a tissue graft or implant comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. The composition and/or tissue graft or implant of the invention is usable in combination with seeded cells, a tissue growth factor, and/or a chemotactic gent to attract a desired cell.
    Type: Grant
    Filed: July 16, 2018
    Date of Patent: October 27, 2020
    Assignee: RTI Surgical, Inc.
    Inventors: C. Randal Mills, John R. Bianchi, Michael R. Roberts, David T. Cheung, Chandrasekaran Nataraj, John W. Howell, Jr.
  • Publication number: 20180326119
    Abstract: The present invention is directed to a composition comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. Also disclosed is a tissue graft or implant comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. The composition and/or tissue graft or implant of the invention is usable in combination with seeded cells, a tissue growth factor, and/or a chemotactic gent to attract a desired cell.
    Type: Application
    Filed: July 16, 2018
    Publication date: November 15, 2018
    Inventors: C. Randal Mills, John R. Bianchi, Michael R. Roberts, David T. Cheung, Chandrasekaran Nataraj, John W. Howell, JR.
  • Patent number: 10022472
    Abstract: The present invention is directed to a composition comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. Also disclosed is a tissue graft or implant comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. The composition and/or tissue graft or implant of the invention is usable in combination with seeded cells, a tissue growth factor, and/or a chemotactic gent to attract a desired cell.
    Type: Grant
    Filed: June 24, 2016
    Date of Patent: July 17, 2018
    Assignee: RTI Surgical, Inc.
    Inventors: C. Randal Mills, John R. Bianchi, Michael R. Roberts, David T. Cheung, Chandrasekaran Nataraj, John W. Howell, Jr.
  • Publication number: 20110091516
    Abstract: The present invention is directed to a composition comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. Also disclosed is a tissue graft or implant comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. The composition and/or tissue graft or implant of the invention is usable in combination with seeded cells, a tissue growth factor, and/or a chemotactic gent to attract a desired cell.
    Type: Application
    Filed: September 9, 2010
    Publication date: April 21, 2011
    Applicant: Regeneration Technologies, Inc.
    Inventors: C. Randal Mills, John R. Bianchi, Michael R. Roberts, David T. Cheung, Chandrasekaran Nataraj, John W. Howell, JR.
  • Patent number: 7883541
    Abstract: The present invention is directed to a composition comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. Also disclosed is a tissue graft or implant comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. The composition and/or tissue graft or implant of the invention is usable in combination with seeded cells, a tissue growth factor, and/or a chemotactic agent to attract a desired cell.
    Type: Grant
    Filed: December 3, 2007
    Date of Patent: February 8, 2011
    Assignee: RTI Biologics, Inc.
    Inventors: C. Randal Mills, John R. Bianchi, Michael R. Roberts, David T. Cheung, Chandrasekaran Nataraj, John W. Howell, Jr.
  • Patent number: 7131994
    Abstract: The present invention is directed to a composition comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. Also disclosed is a tissue graft or implant comprising a matrix suitable for implantation in humans, comprising defatted, shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier and dried in a predetermined shape. The composition and/or tissue graft or implant of the invention is usable in combination with seeded cells, a tissue growth factor, and/or a chemotactic agent to attract a desired cell.
    Type: Grant
    Filed: March 5, 2004
    Date of Patent: November 7, 2006
    Assignee: Regeneration Technologies, Inc.
    Inventors: C. Randal Mills, John R. Bianchi, Michael R. Roberts, David T. Cheung, Chandrasekaran Nataraj, John W. Howell, Jr.
  • Patent number: 7001430
    Abstract: The present invention is directed to an intermediate composition for producing a muscle tissue matrix suitable for implantation in humans, comprising shredded, allogeneic human muscle tissue that has been combined with an aqueous carrier, preferably a biocompatible acid solution, to form a muscle tissue slurry having a viscosity within the range of 1 centistoke to 20,000 centistokes measured at 25° C. In another aspect, the present invention is directed to a tissue implant comprising a human muscle tissue matrix.
    Type: Grant
    Filed: January 9, 2004
    Date of Patent: February 21, 2006
    Assignee: Regeneration Technologies, Inc.
    Inventors: C. Randal Mills, John R. Bianchi, Michael R. Roberts, David T. Cheung, Chandrasekaran Nataraj, John W. Howell, Jr.