Abstract: A system including a deep learning processor receives one or more control signals from one or more of a factory's process, equipment and control (P/E/C) systems during a manufacturing process. The processor generates expected response data and expected behavioral pattern data for the control signals. The processor receives production response data from the one or more of the factory's P/E/C systems and generates production behavioral pattern data for the production response data. The process compares at least one of: the production response data to the expected response data, and the production behavioral pattern data to the expected behavioral pattern data to detect anomalous activity. As a result of detecting anomalous activity, the processor performs one or more operations to provide notice or cause one or more of the factory's P/E/C systems to address the anomalous activity.

Abstract: A catheter with a guide wire and handle is provided for sampling an area of interest, such as chorionic villi. The catheter contains a cannula of flexible plastic that is non-pyrogenic and latex-free, and a flexible obturator with an elongate cylindrical handle. The cannula is echogenic and can be easily visualized with visualization or imaging device. In an embodiment, the catheter may be curved manually by the operator to conform to the patient's anatomy and it is inserted through the cervix into a pregnant uterus at 10-13 weeks gestation and placed into the developing placenta under ultrasound guidance and a guide mechanism provided on the handle. In this embodiment, once the catheter has been placed, the obturator is withdrawn and a sample of chorionic villi is removed by applying appropriate pressure to the proximal end of the cannula and slowly withdrawing the cannula from the uterine cavity.

Abstract: A catheter with a guide wire and handle is provided for sampling an area of interest, such as chorionic villi. The catheter contains a cannula of flexible plastic that is non-pyrogenic and latex-free, and a flexible obturator with an elongate cylindrical handle. The cannula is echogenic and can be easily visualized with visualization or imaging device. In an embodiment, the catheter may be curved manually by the operator to conform to the patient's anatomy and it is inserted through the cervix into a pregnant uterus at 10-13 weeks gestation and placed into the developing placenta under ultrasound guidance and a guide mechanism provided on the handle. In this embodiment, once the catheter has been placed, the obturator is withdrawn and a sample of chorionic villi is removed by applying appropriate pressure to the proximal end of the cannula and slowly withdrawing the cannula from the uterine cavity.