Abstract: A mining machine includes a chassis, a boom, a cutting head, and a shield supported for movement relative to the chassis. The chassis includes a first end and a second end, and defines a longitudinal axis extending between the first end and the second end. The boom includes a first end and a second end, and the boom is supported for movement relative to the chassis. The boom translates in a first direction and is pivotable relative to the chassis between first and second positions. The cutting head is coupled to the second end of the boom and is supported for rotation relative to the boom. The cutting head is rotatable about a cutting head axis. The shield is supported for movement relative to the chassis and positioned proximate the cutting head. In some embodiments, the shield is coupled to a sumping frame supported for movement relative to the chassis.

Abstract: A mining machine includes a chassis, a boom, a cutting head, and a shield supported for movement relative to the chassis. The chassis includes a first end and a second end, and defines a longitudinal axis extending between the first end and the second end. The boom includes a first end and a second end, and the boom is supported for movement relative to the chassis. The boom translates in a first direction and is pivotable relative to the chassis between first and second positions. The cutting head is coupled to the second end of the boom and is supported for rotation relative to the boom. The cutting head is rotatable about a cutting head axis. The shield is supported for movement relative to the chassis and positioned proximate the cutting head. In some embodiments, the shield is coupled to a sumping frame supported for movement relative to the chassis.

Abstract: A mining machine includes a boom, a cutter head, a valve, and an actuator. The boom defines an internal chamber and includes a first end coupled to a frame, a second end, and an opening in fluid communication with the internal chamber. The cutter head includes a plurality of cutting bits and is supported on the second end of the boom. The valve is coupled to the boom and is movable between a closed position in which the opening is covered and an open position in which the opening is at least partially uncovered. The actuator is coupled to the valve to selectively move the valve between the closed position and the opened position.

Abstract: A mining machine includes a boom, a cutter head, a valve, and an actuator. The boom defines an internal chamber and includes a first end coupled to a frame, a second end, and an opening in fluid communication with the internal chamber. The cutter head includes a plurality of cutting bits and is supported on the second end of the boom. The valve is coupled to the boom and is movable between a closed position in which the opening is covered and an open position in which the opening is at least partially uncovered. The actuator is coupled to the valve to selectively move the valve between the closed position and the opened position.

Abstract: A mining machine includes a boom, a cutter head, a valve, and an actuator. The boom defines an internal chamber and includes a first end coupled to a frame, a second end, and an opening in fluid communication with the internal chamber. The cutter head includes a plurality of cutting bits and is supported on the second end of the boom. The valve is coupled to the boom and is movable between a closed position in which the opening is covered and an open position in which the opening is at least partially uncovered. The actuator is coupled to the valve to selectively move the valve between the closed position and the opened position.

Abstract: A mining machine includes a boom, a cutter head, a valve, and an actuator. The boom defines an internal chamber and includes a first end coupled to a frame, a second end, and an opening in fluid communication with the internal chamber. The cutter head includes a plurality of cutting bits and is supported on the second end of the boom. The valve is coupled to the boom and is movable between a closed position in which the opening is covered and an open position in which the opening is at least partially uncovered. The actuator is coupled to the valve to selectively move the valve between the closed position and the opened position.

Abstract: The present invention provides the use of an inhibitor of glycolipid biosynthesis in the manufacture of a medicament for the treatment of a glycolipid-mediated autoimmune disease.