Patents by Inventor Jon M. Huibregtse

Jon M. Huibregtse has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • E6 associated protein
    Patent number: 5914389
    Abstract: The present invention provides compositions of isolated and purified E6 Associated Protein and fragments thereof. Also provided are nucleic acid constructs encoding E6 Associated Protein. These compositions may be employed to identify compounds which inhibit binding of high risk HPV E6 to p53. The compositions of the present invention may also be used in methods to detect the presence of high risk HPV in biological samples.
    Type: Grant
    Filed: July 1, 1996
    Date of Patent: June 22, 1999
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Jon M. Huibregtse, Martin Scheffner, Peter M. Howley
  • E6 associated protein and methods of use thereof
    Patent number: 5532348
    Abstract: The present invention provides compositions of isolated and purified E6 Associated Protein and fragments thereof. Also provided are nucleic acid constructs encoding E6 Associated Protein. These compositions may be employed to identify compounds which inhibit binding of high risk HPV E6 to p53. The compositions of the present invention may also be used in methods to detect the presence of high risk HPV in biological samples.
    Type: Grant
    Filed: July 30, 1993
    Date of Patent: July 2, 1996
    Assignee: United States of America
    Inventors: Jon M. Huibregtse, Martin Scheffner, Peter M. Howley