Patents by Inventor Jon S. Morrow

Jon S. Morrow has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ultra-sensitive detection systems using alterable peptide tags
    Patent number: 6824981
    Abstract: Disclosed are compositions and methods for sensitive detection of one or multiple analytes. In general, the methods involve the use of special label components, referred to as reporter signals, that can be associated with, incorporated into, or otherwise linked to the analytes. In some embodiments, the reporter signals can be altered such that the altered forms of different reporter signals can be distinguished from each other. In some embodiments, sets of reporter signals can be used where two or more of the reporter signals in a set have one or more common properties that allow the reporter signals having the common property to be distinguished and/or separated from other molecules lacking the common property.
    Type: Grant
    Filed: August 13, 2001
    Date of Patent: November 30, 2004
    Assignee: Agilix Corporation
    Inventors: Brian T. Chait, Darin R. Latimer, Paul M. Lizardi, Eric R. Kershnar, Jon S. Morrow, Matthew E. Roth, Martin J. Mattessich, Kevin J. McConnell
  • Ultra-sensitive detection systems
    Publication number: 20030045694
    Abstract: Disclosed are compositions and methods for sensitive detection of one or multiple analytes. In general, the methods involve the use of special label components, referred to as reporter signals, that can be associated with, incorporated into, or otherwise linked to the analytes. In some embodiments, the reporter signals can be altered such that the altered forms of different reporter signals can be distinguished from each other. In some embodiments, sets of reporter signals can be used where two or more of the reporter signals in a set have one or more common properties that allow the reporter signals having the common property to be distinguished and/or separated from other molecules lacking the common property.
    Type: Application
    Filed: August 13, 2001
    Publication date: March 6, 2003
    Inventors: Brian T. Chait, Darin R. Latimer, Paul M. Lizardi, Eric R. Kershnar, Jon S. Morrow, Matthew E. Roth, Martin J. Mattessich, Kevin J. McConnell
  • Structure of the ankyrin binding domain of a &agr;-Na, K-ATPase
    Patent number: 6485935
    Abstract: The present invention provides a polypeptide of 26 amino acid residues that comprises the minimal ankyrin binding (MAB) domain. The MAB domain is responsible for the interactions between a Na,K-ATPase and ankyrin. The present invention also provides the three dimensional structure of the MAB domain. Also provided by the present invention are methods for modulating the interaction of a Na,K-ATPase and ankyrin.
    Type: Grant
    Filed: January 11, 2000
    Date of Patent: November 26, 2002
    Assignee: Yale University
    Inventors: Jon S. Morrow, Prasad Devarajan, Zhushan Zhang
  • Polynucleotides encoding ankyrin proteins
    Patent number: 6225086
    Abstract: A novel cytoplasmic ankyrin protein is disclosed along with methods for selectively identifying ankyrin proteins that participate in the trafficking of integral membrane proteins and secretory proteins between the endoplasmic reticulum, Golgi and other membrane compartments. Nucleic acid and protein sequences are disclosed, along with methods for identifying agents that modulate the binding of ankyrins to their binding partners.
    Type: Grant
    Filed: May 21, 1998
    Date of Patent: May 1, 2001
    Assignee: Yale University
    Inventors: Jon S. Morrow, Prasad Devarajan