Patents by Inventor Jonathan Ahab Sheps

Jonathan Ahab Sheps has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINATION OF A POLYHYDROXYLATED BILE ACID AND A FARNESOID X RECEPTOR AGONIST
    Publication number: 20220227804
    Abstract: The present invention relates to, in part, a combination therapy of a polyhydroxylated bile acid and a farnesoid X receptor agonist. The present invention also provides, in part, a pharmaceutical composition comprising a farnesoid X receptor agonist and a polyhydroxylated bile acid in the preparation of a medicament for treating a biliary disorder or a gastrointestinal disorder.
    Type: Application
    Filed: May 29, 2020
    Publication date: July 21, 2022
    Inventors: Victor LING, Lin LIU, Jonathan Ahab SHEPS, Renxue WANG
  • POLYHYDROXYLATED BILE ACIDS FOR TREATMENT OF BILIARY DISORDERS
    Publication number: 20200078374
    Abstract: The invention provides, in part, polyhydroxylated bile adds for treating biliary disorders, for example, biliary disorders arising out of cholestasis of portal hypertension. The invention also provides, in part, polyhydroxylated bile acids for stimulating bile flow. New compounds 2?,3?,7?,12?-tetrahydroxy-5?-cholanoic acid and 3?,4?,7?,12?-tetrahydroxy-5?-cholanoic acid are disclosed, uses thereof and synthesis thereof.
    Type: Application
    Filed: November 25, 2019
    Publication date: March 12, 2020
    Inventors: Victor LING, Renxue WANG, Jonathan Ahab SHEPS
  • Polyhydroxylated bile acids for treatment of biliary disorders
    Patent number: 10543220
    Abstract: The invention provides, in part, polyhydroxylated bile acids for treating biliary disorders, for example, biliary disorders arising out of cholestasis of portal hypertension. The invention also provides, in part, polyhydroxylated bile acids for stimulating bile flow. New compounds 2?, 3?, 7?, 12?-tetrahydroxy-5?-cholanoic acid and 3?. 4?, 7?, 12?-tetrahydroxy-5?-cholanoic acid are disclosed, uses thereof and synthesis thereof.
    Type: Grant
    Filed: December 21, 2015
    Date of Patent: January 28, 2020
    Assignee: Qing Bile Therapeutics Inc.
    Inventors: Victor Ling, Renxue Wang, Jonathan Ahab Sheps
  • POLYHYDROXYLATED BILE ACIDS FOR TREATMENT OF BILIARY DISORDERS
    Publication number: 20160184325
    Abstract: The invention provides, in part, polyhydroxylated bile acids for treating biliary disorders, for example, biliary disorders arising out of cholestasis of portal hypertension. The invention also provides, in part, polyhydroxylated bile acids for stimulating bile flow. New compounds 2?, 3?, 7?, 12?-tetrahydroxy-5?-cholanoic acid and 3?, 4?, 7?, 12?-tetrahydroxy-5?-cholanoic acid are disclosed, uses thereof and synthesis thereof.
    Type: Application
    Filed: December 21, 2015
    Publication date: June 30, 2016
    Inventors: Victor Ling, Renxue Wang, Jonathan Ahab Sheps
  • Polyhydroxylated bile acids for treatment of biliary disorders
    Patent number: 9295677
    Abstract: The invention provides, in part, polyhydroxylated bile acids for treating biliary disorders, for example, biliary disorders arising out of cholestasis of portal hypertension. The invention also provides, in part, polyhydroxylated bile acids for stimulating bile flow. New compounds 2?,3?,7?,12?-tetrahydroxy-5?-cholanoic acid and 3?.4?,7?,12?-tetrahydroxy-5?-cholanoic acid are disclosed, uses thereof and synthesis thereof.
    Type: Grant
    Filed: February 27, 2012
    Date of Patent: March 29, 2016
    Assignee: Qing Bile Therapeutics Inc.
    Inventors: Victor Ling, Renxue Wang, Jonathan Ahab Sheps
  • POLYHYDROXYLATED BILE ACIDS FOR TREATMENT OF BILIARY DISORDERS
    Publication number: 20120277198
    Abstract: The invention provides, in part, polyhydroxylated bile acids for treating biliary disorders, for example, biliary disorders arising out of cholestasis of portal hypertension. The invention also provides, in part, polyhydroxylated bile acids for stimulating bile flow. New compounds 2?,3?,7?,12?-tetrahydroxy-5?-cholanoic acid and 3?.4?,7?,12?-tetrahydroxy-5?-cholanoic acid are disclosed, uses thereof and synthesis thereof.
    Type: Application
    Filed: February 27, 2012
    Publication date: November 1, 2012
    Inventors: VICTOR LING, RENXUE WANG, JONATHAN AHAB SHEPS
  • Polyhydroxylated Bile Acids for Treatment of Biliary Disorders
    Publication number: 20110263546
    Abstract: The invention provides, in part, polyhydroxylated bile acids for treating biliary disorders, for example, biliary disorders arising out of cholestasis or portal hypertension. The invention also provides, in part, polyhydroxylated bile acids for stimulating bile flow.
    Type: Application
    Filed: February 26, 2009
    Publication date: October 27, 2011
    Inventors: Renxue Wang, Victor Ling, Jonathan Ahab Sheps