Patents by Inventor Jonathan Busolli

Jonathan Busolli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystalline forms of pemetrexed diacid and processes for the preparation thereof
    Patent number: 9718829
    Abstract: Provided are crystalline forms of N-[4-[2-(2-amino-4, 7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]ben-zoyl]-L-glutamic acid, pemetrexed diacid, and processes for the preparation thereof.
    Type: Grant
    Filed: November 23, 2016
    Date of Patent: August 1, 2017
    Assignee: Sicor Inc.
    Inventors: Jonathan Busolli, Nicola Diulgheroff, Csilla Nemethne Racz, Moran Pirkes, Alessandro Pontiroli, Marco Villa, Judith Aronhime
  • Crystalline Forms Of Pemetrexed Diacid And Processes For The Preparation Thereof
    Publication number: 20170129900
    Abstract: Provided are crystalline forms of N-[4-[2-(2-amino-4, 7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]ben-zoyl]-L-glutamic acid, pemetrexed diacid, and processes for the preparation thereof.
    Type: Application
    Filed: November 23, 2016
    Publication date: May 11, 2017
    Inventors: Jonathan Busolli, Nicola Diulgheroff, Csilla Nemethne Racz, Moran Pirkes, Alessandro Pontiroli, Marco Villa, Judith Aronhime
  • Crystalline forms of pemetrexed diacid and processes for the preparation thereof
    Patent number: 9562050
    Abstract: Provided are crystalline forms of N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]ben-zoyl]-L-glutamic acid, pemetrexed diacid, and processes for the preparation thereof.
    Type: Grant
    Filed: September 16, 2015
    Date of Patent: February 7, 2017
    Assignee: Sicor, Inc.
    Inventors: Jonathan Busolli, Nicola Diulgheroff, Csilla Nemethne Racz, Moran Pirkes, Alessandro Pontiroli, Marco Villa, Judith Aronhime
  • Crystalline Forms Of Pemetrexed Diacid And Processes For The Preparation Thereof
    Publication number: 20160002253
    Abstract: Provided are crystalline forms of N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]ben-zoyl]-L-glutamic acid, pemetrexed diacid, and processes for the preparation thereof.
    Type: Application
    Filed: September 16, 2015
    Publication date: January 7, 2016
    Inventors: Jonathan Busolli, Nicola Diulgheroff, Csilla Nemethne Racz, Moran Pirkes, Alessandro Pontiroli, Marco Villa, Judith Aronhime
  • Crystalline forms of pemetrexed diacid and processes for the preparation thereof
    Patent number: 9156841
    Abstract: Provided are crystalline forms of N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid, pemetrexed diacid, and processes for the preparation thereof.
    Type: Grant
    Filed: March 23, 2011
    Date of Patent: October 13, 2015
    Assignee: Sicor Inc.
    Inventors: Jonathan Busolli, Nicola Diulgheroff, Csilla Nemethne Racz, Moran Pirkes, Alessandro Pontiroli, Marco Villa, Judith Aronhime
  • Processes for the preparation of lyophilized pharmaceutically acceptable salts of pemetrexed diacid
    Patent number: 8629152
    Abstract: Provided are processes for the preparation of lyophilized pharmaceutically acceptable salts of pemetrexed diacid, in particular, pemetrexed disodium salt, directly from pemetrexed diacid or salts thereof, i.e., without isolating the obtained pemetrexed salt prior to lyophilizing it.
    Type: Grant
    Filed: August 14, 2007
    Date of Patent: January 14, 2014
    Assignee: Sicor, Inc.
    Inventors: Jonathan Busolli, Nicola Diulgheroff, Moran Pirkes, Alessandro Pontiroli, Marco Villa, Zvi Harel
  • Process for the preparation of tiotropium bromide
    Patent number: 8378103
    Abstract: The invention is directed to improved processes for preparing Tiotropium bromide.
    Type: Grant
    Filed: January 4, 2010
    Date of Patent: February 19, 2013
    Assignee: Sicor, Inc.
    Inventors: Jonathan Busolli, Nicola Diulgheroff, Francesca Scarpitta, Roberta Volonte, Alessandro Pontiroli
  • Process for the preparation of tiotropium bromide
    Patent number: 8344143
    Abstract: The invention is directed to improved processes for preparing Tiotropium bromide.
    Type: Grant
    Filed: December 23, 2009
    Date of Patent: January 1, 2013
    Assignee: Sicor, Inc.
    Inventors: Jonathan Busolli, Nicola Diulgheroff, Francesca Scarpitta, Roberta Volonte, Alessandro Pontiroli
  • Crystalline forms of pemetrexed diacid and processes for the preparation thereof
    Patent number: 8088919
    Abstract: Provided are crystalline forms of N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid, pemetrexed diacid, and processes for the preparation thereof.
    Type: Grant
    Filed: August 14, 2007
    Date of Patent: January 3, 2012
    Assignee: Sicor Inc.
    Inventors: Jonathan Busolli, Nicola Diulgheroff, Csilla Nemethne Racz, Moran Pirkes, Alessandro Pontiroli, Marco Villa, Judith Aronhime
  • CRYSTALLINE FORMS OF PEMETREXED DIACID AND PROCESSES FOR THE PREPARATION THEREOF
    Publication number: 20110196155
    Abstract: Provided are crystalline forms of N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid, pemetrexed diacid, and processes for the preparation thereof.
    Type: Application
    Filed: March 23, 2011
    Publication date: August 11, 2011
    Applicant: SICOR INC.
    Inventors: Jonathan BUSOLLI, Nicola DIULGHEROFF, Csilla Nemethne Racz, Moran PIRKES, Alessandro PONTIROLI, Marco VILLA, Judith ARONHIME
  • PROCESS FOR THE PREPARATION OF TIOTROPIUM BROMIDE
    Publication number: 20100105913
    Abstract: The invention is directed to improved processes for preparing Tiotropium bromide.
    Type: Application
    Filed: January 4, 2010
    Publication date: April 29, 2010
    Applicant: SICOR, INC.
    Inventors: Jonathan BUSOLLI, Nicola DIULGHEROFF, Francesca SCARPITTA, Roberta VOLONTE, Alessandro PONTIROLI
  • PROCESS FOR THE PREPARATION OF TIOTROPIUM BROMIDE
    Publication number: 20100099867
    Abstract: The invention is directed to improved processes for preparing Tiotropium bromide.
    Type: Application
    Filed: December 23, 2009
    Publication date: April 22, 2010
    Applicant: SICOR, INC.
    Inventors: Jonathan BUSOLLI, Nicola DIULGHEROFF, Francesca SCARPITTA, Roberta VOLONTE, Alessandro PONTIROLI
  • Process for the preparation of tiotropium bromide
    Patent number: 7662963
    Abstract: The invention is directed to improved processes for preparing Tiotropium bromide.
    Type: Grant
    Filed: March 13, 2009
    Date of Patent: February 16, 2010
    Assignee: Sicor Inc.
    Inventors: Jonathan Busolli, Nicola Diulgheroff, Francesca Scarpitta, Roberta Volonte, Alessandro Pontiroli
  • PROCESS FOR THE PREPARATION OF TIOTROPIUM BROMIDE
    Publication number: 20090247747
    Abstract: The invention is directed to improved processes for preparing Tiotropium bromide.
    Type: Application
    Filed: March 13, 2009
    Publication date: October 1, 2009
    Applicant: SICOR, INC.
    Inventors: Jonathan BUSOLLI, Nicola DIULGHEROFF, Francesca SCARPITTA, Roberta VOLONTE, Alessandro PONTIROLI
  • Highly pure pemetrexed Diacid and processes for the preparation thereof
    Publication number: 20090012294
    Abstract: Provided are highly pure pemetrexed diacid and pharmaceutically acceptable salts thereof, and processes for their preparation.
    Type: Application
    Filed: March 28, 2008
    Publication date: January 8, 2009
    Inventors: Nicola Diulgheroff, Moran Pirkes, Alessandro Pontiroli, Marco Villa, Jonathan Busolli, Roberto Casalone
  • Processes for the preparation of lyophilized pharmaceutically acceptable salts of pemetrexed diacid
    Publication number: 20080139810
    Abstract: Provided are processes for the preparation of lyophilized pharmaceutically acceptable salts of pemetrexed diacid, in particular, pemetrexed disodium salt, directly from pemetrexed diacid or salts thereof, i.e., without isolating the obtained pemetrexed salt prior to lyophilizing it.
    Type: Application
    Filed: August 14, 2007
    Publication date: June 12, 2008
    Inventors: Jonathan Busolli, Nicola Diulgheroff, Moran Pirkes, Alessandro Pontiroli, Marco Villa
  • Process for the preparation of tiotropium bromide
    Publication number: 20080051582
    Abstract: The invention is directed to improved processes for preparing Tiotropium bromide.
    Type: Application
    Filed: July 10, 2007
    Publication date: February 28, 2008
    Applicant: Sicor Inc.
    Inventors: Jonathan Busolli, Nicola Diulgheroff, Francesca Scarpitta, Roberta Volonte, Alessandro Pontiroli
  • Crystalline forms of pemetrexed diacid and processes for the preparation thereof
    Publication number: 20080045711
    Abstract: Provided are crystalline forms of N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid, pemetrexed diacid, and processes for the preparation thereof.
    Type: Application
    Filed: August 14, 2007
    Publication date: February 21, 2008
    Inventors: Jonathan Busolli, Nicola Diulgheroff, Csilla Nemethne Racz, Moran Pirkes, Alessandro Pontiroli, Marco Villa, Judith Aronhime