Abstract: The invention relates to compounds of formula I wherein R1, R2 and - - - - - are as defined herein, pharmaceutical compositions comprising the compounds and methods of treating COVID-19 in a patient by administering therapeutically effective amounts of the compounds and methods of inhibiting or preventing replication of SARS-CoV-2 with the compounds.

Abstract: A document management system (10) includes a content repository (14) for storing a file, a management system (12) for monitoring and managing the file in the content repository (14), and an authoring portal (15). The authoring portal (15) embeds ActiveX controls in a document, parses the document, and converts the document into an HTML file. The authoring portal (15) further generates JavaScript codes, thereby enabling the content repository (14) to dynamically respond the input of a user and provide the user with feedback without accessing a database associated with the document. The codes also enable the content repository (14) to dynamically adjust the sequence in which the documents are presented to the user in response to the inputs from the user.

Abstract: A data transfer and management process includes transferring an XML string representing a tree structure of a folder from a network server (12) to a client station (14A) in response to a request at the client station for accessing the folder. The transferred XML string includes the information regarding all subfolders and the names of all files in the folder, but not the content of the files in the folder. At the client station (14A), the XML string is parsed on demand to generate JavaScript codes to present the descendents of a folder in response to a request for accessing the folder, which may be a root folder or a branch folder. In response to a request of accessing a file in the folder, the client station (14A) initiates a process for transferring the content of the file from the network server (12).