Abstract: A portable, non-invasive device for providing therapeutic treatment to a joint to promote healing of the joint includes a cuff positionable around the joint, a pouch coupled to the cuff and sized to receive a first thermal therapy component including at least two substances in separate compartments separated by a breakable barrier, wherein the at least two substances are configured to react upon mixing to produce thermal energy exchangeable with the joint, and a holder coupled to the cuff and configured to mechanically, removably receive a disposable housing including a second thermal therapy component.