Abstract: Provided herein are KRAS G12C inhibitors, composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.

Abstract: The formation of amorphous silicon for use in, for example, lithium-ion batteries is disclosed. The process can include milling a plurality of silicon nanocrystals having an average particle diameter and a percent crystallinity greater than about 60%, in a unit designed to reduce the average particle diameter to the same or a larger size, thereby forming a plurality of amorphous silicon nanoparticles having about the same average particle diameter as the silicon nanocrystals and a percent crystallinity of less than about 50%.

Abstract: A method for establishing a trusted session between a first computing device and a computer server includes obtaining identifying information for the first computing device and a second computing device. The identifying information includes identifying information corresponding to the networks to which each of the computing devices are directly connected. Based on the identifying information it may be determined that there is sufficient correspondence between the first and second computing devices. If so, an indication is sent to the second computing device requesting confirmation that the first computing device should be authenticated to the account. An indication confirming this may then be received and, responsive thereto, the first computing device is authenticated to the account. Related computer systems and computer-readable media are also disclosed.

Abstract: Composite anode-active particulates that include lithium-active, silicon nanoparticles in carbon matrices impregnated with solid electrolyte are described with methods for their preparation. The composite active particulates preferably include a solid electrolyte phase carried within pores of the particulate.

Abstract: Composite anode-active particulates that include lithium-active, silicon nanoparticles in carbon matrices impregnated with solid electrolyte are described with methods for their preparation. The composite active particulates preferably include a solid electrolyte phase carried within pores of the particulate.

Abstract: Porous particulates for use in lithium ion batteries are described. The porous materials include silicon active materials carried in a carbon matrix that includes a solid-electrolyte phase. The combined matrix of the carbon and solid-electrolyte carries silicon nanoparticles and conducts lithium ions and electrons. The manufacture and use are further described.

Abstract: Herewith is described a process to produce stable, non-pyrophoric silicon nanocrystals as an isolatable powder. The process includes comminuting a silicon feed in a solvent thereby forming a silicon nanoparticle slurry, admixing a dry (water free) reagent with the silicon nanoparticle slurry thereby forming a SiX-coated silicon nanoparticle slurry. The reagent is, preferably, selected from an oxide source, a sulfide source, or a carbide source; where the SiX-coated silicon nanoparticle includes a SiX coating on a silicon nanoparticle and the SiX coating is a silicon-oxide when the reagent is an oxide source, a silicon-sulfide when the reagent is a sulfide source, or a silicon-carbide when the reagent is a carbide source.

Abstract: A method for establishing a trusted session between a first computing device and a computer server includes obtaining identifying information for the first computing device and a second computing device. The identifying information includes identifying information corresponding to the networks to which each of the computing devices are directly connected. Based on the identifying information it may be determined that there is sufficient correspondence between the first and second computing devices. If so, an indication is sent to the second computing device requesting confirmation that the first computing device should be authenticated to the account. An indication confirming this may then be received and, responsive thereto, the first computing device is authenticated to the account. Related computer systems and computer-readable media are also disclosed.

Abstract: A process for the controlled synthesis of silicon carbide reinforced secondary particles is provided. The process includes forming an microaggregate from an admixing a plurality of silicon nanoparticles, a plurality of silicon oxide nanoparticles, a carbon source, and a fiber-catalyst and then thermalizing the microaggregate and forming silicon carbide nanofibers throughout a resulting spherical microcomposite (silicon carbide reinforced secondary particle).

Abstract: The formation of amorphous silicon for use in, for example, lithium-ion batteries is disclosed. The process can include milling a plurality of silicon nanocrystals having an average particle diameter and a percent crystallinity greater than about 60%, in a unit designed to reduce the average particle diameter to the same or a larger size, thereby forming a plurality of amorphous silicon nanoparticles having about the same average particle diameter as the silicon nanocrystals and a percent crystallinity of less than about 50%.

Abstract: Composite anode-active particulates that include lithium-active, silicon nanoparticles in carbon matrices impregnated with solid electrolyte are described with methods for their preparation. The composite active particulates preferably include a solid electrolyte phase carried within pores of the particulate.

Abstract: A method for establishing a trusted session between a first computing device and a computer server includes obtaining identifying information for the first computing device and a second computing device. The identifying information includes identifying information corresponding to the networks to which each of the computing devices are directly connected. Based on the identifying information it may be determined that there is sufficient correspondence between the first and second computing devices. If so, an indication is sent to the second computing device requesting confirmation that the first computing device should be authenticated to the account. An indication confirming this may then be received and, responsive thereto, the first computing device is authenticated to the account. Related computer systems and computer-readable media are also disclosed.

Abstract: Herein are described compositions, anodes and batteries utilizing a plurality of amorphous silicon nanocrystals and a solid electrolyte. These compositions provide anode and batteries that have improved first columbic efficiencies when compared to analogous systems prepared with crystalline silicon nanocrystals. The methods of the production of the admixtures, the anodes and the cells/batteries are also provided.

Abstract: Compositions, anodes, and batteries are described herein and incorporate particulates that feature carbon matrices having embedded therein a plurality of amorphous silicon nanoparticles. One embodiment includes a particulate composed of a porous carbon matrix and a plurality of amorphous silicon nanoparticles affixed to an interior surface of the porous carbon matrix and adjacent to an open volume that defines specific pores. Yet another embodiment is an anode active particulate that features a plurality of amorphous silicon nanoparticles affixed to interior surfaces of a porous carbon matrix, where the anode active particulate has a “Standard-FCE” value that is about 5% greater than a “Standard-FCE” value of an analogous anode active particle having crystalline silicon nanocrystals.

Abstract: A method for establishing a trusted session between a first computing device and a computer server includes obtaining identifying information for the first computing device and a second computing device. The identifying information includes identifying information corresponding to the networks to which each of the computing devices are directly connected. Based on the identifying information it may be determined that there is sufficient correspondence between the first and second computing devices. If so, an indication is sent to the second computing device requesting confirmation that the first computing device should be authenticated to the account. An indication confirming this may then be received and, responsive thereto, the first computing device is authenticated to the account. Related computer systems and computer-readable media are also disclosed.

Abstract: Compositions, anodes, and batteries are described herein and incorporate particulates that feature carbon matrices having embedded therein a plurality of amorphous silicon nanoparticles. One embodiment includes a particulate composed of a porous carbon matrix and a plurality of amorphous silicon nanoparticles affixed to an interior surface of the porous carbon matrix and adjacent to an open volume that defines specific pores. Yet another embodiment is an anode active particulate that features a plurality of amorphous silicon nanoparticles affixed to interior surfaces of a porous carbon matrix, where the anode active particulate has a “Standard-FCE” value that is about 5% greater than a “Standard-FCE” value of an analogous anode active particle having crystalline silicon nanocrystals.

Abstract: Processes for the manufacture of porous particulates for use in lithium ion batteries are described. The porous materials include silicon active materials carried in a continuous matrix that includes a carbon phase and a solid-electrolyte phase.

Abstract: Solid state compositions for use in an anode of a secondary battery, anodes, and lithium ion batteries are provided which include silicon carbide nanofibers, preferably carried in and reinforcing both an anode active material and a solid electrolyte. Methods of production and use are further described.

Abstract: The process of bi-functionalizing silicon nanoparticles and bi-functionalized silicon nanoparticles are described. The processes include applying shear forces to silicon metal in the presence of an alkane, thereby providing an alkyl-hydride-functionalized silicon nanoparticle, which is then treated with a reactant, e.g., a compound that reacts with the hydride functionality, to provide the bi-functionalized silicon nanoparticles. The resulting product can include a plurality of functionalities on a silicon nanoparticle derived from alkenes, alkynes, aldehydes, alcohols, thiols, amines, carboxylates, and/or carboxylic acids.

Abstract: The mechanochemical functionalization of silicon nanoparticles and functionalized silicon nanoparticles are described. The processes include applying shear forces to silicon metal the presence of an alkane and thereby functionalizing the silicon with an alkyl-functionalization, preferably an alkyl-hydride-functionalization. The resulting product includes a plurality of silicon nanoparticles each carrying an alkyl-functionalization, and preferably a hydride-functionalization, derived from an alkane.