Patents by Inventor Jonathan Hofmekler

Jonathan Hofmekler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11311429
    Abstract: Methods and products for maintaining a target pH range of an environment including at least one organism are provided. A method can include releasing a carbon source to the environment. A method can further include allowing the carbon source to be metabolized by the at least one organism and lower a pH of the environment. The method can also include releasing a nitrogen source to the environment. The method can additionally include allowing the nitrogen source to be metabolized by the at least one organism and increase the pH of the environment. The releasing of the carbon source to the environment and the releasing of the nitrogen source to the environment can be selectively timed to control the pH of the environment to the target pH range of the environment.
    Type: Grant
    Filed: January 31, 2019
    Date of Patent: April 26, 2022
    Assignee: Kimberly-Clark Worldwide, Inc.
    Inventors: David W. Koenig, Jonathan Hofmekler, Lindsay A. Peed, Jeffery R. Seidling, Scott W. Wenzel
  • Publication number: 20220096287
    Abstract: Methods and products for maintaining a target pH range of an environment including at least one organism are provided. A method can include releasing a carbon source to the environment. A method can further include allowing the carbon source to be metabolized by the at least one organism and lower a pH of the environment. The method can also include releasing a nitrogen source to the environment. The method can additionally include allowing the nitrogen source to be metabolized by the at least one organism and increase the pH of the environment. The releasing of the carbon source to the environment and the releasing of the nitrogen source to the environment can be selectively timed to control the pH of the environment to the target pH range of the environment.
    Type: Application
    Filed: January 31, 2019
    Publication date: March 31, 2022
    Applicant: Kimberly-Clark Worldwide, Inc.
    Inventors: David W. Koenig, Jonathan Hofmekler, Lindsay A. Peed, Jeffery R. Seidling, Scott W. Wenzel
  • Publication number: 20210308034
    Abstract: A composition for providing or maintaining a healthy skin microbiota and methods of providing or maintaining a healthy skin microbiota are disclosed. The composition can be a prebiotic composition that can include a carrier and a skin microbiota balancing agent. In some aspects, the skin microbiota balancing agent can include at least one combination of carbohydrate sources including a first carbohydrate source and a second carbohydrate source. The skin microbiota balancing agent can be configured to provide at least two of the following desired ratios: a first desired ratio of Corynebaderium to Staphylococcus of 1.3, a second desired ratio of Corynebaderium to Micrococcus of 1.4, and a third desired ratio of Staphylococcus to Micrococcus of 1.1. The carbohydrate sources may be D-alanine, D-threonine, L-alanyl-glycine, succinic acid, ?-keto-glutaric acid, m-tantaric acid, bromo succinic acid, mucic acid, phenylethyl-amine, inulin, oxalic acid, pectin, Tween 40 etc.
    Type: Application
    Filed: May 22, 2019
    Publication date: October 7, 2021
    Applicant: KIMBERLY-CLARK WORLDWIDE, INC.
    Inventors: Elizabeth M. Doney, David W. Koenig, Jonathan Hofmekler
  • Patent number: 10209256
    Abstract: Lateral-flow assay and time-resolved fluorescence technologies provide a sensitive tool for detecting norovirus particles in a sample. A flow-through assay device employs norovirus and norovirus G2 antibodies. The lateral-flow assay includes a conjugate pad having conjugated probes. The conjugated probes are particles modified with a binding member that is configured to bind with a norovirus. The particles also have a fluorescent label. A general method of detecting the virus includes (i) preparing a sample with contaminants, (ii) processing the sample and depositing it onto the assay device, and (iii) measuring the fluorescence signal.
    Type: Grant
    Filed: November 27, 2014
    Date of Patent: February 19, 2019
    Assignee: Kimberly-Clark Worldwide, Inc.
    Inventors: Bao Trong Do, Jonathan Hofmekler, Cesar A. Morales, David W. Koenig, Yang Huang, Aimin He
  • Publication number: 20170322212
    Abstract: Lateral-flow assay and time-resolved fluorescence technologies provide a sensitive tool for detecting norovirus particles in a sample. A flow-through assay device employs norovirus and norovirus G2 antibodies. The lateral-flow assay includes a conjugate pad having conjugated probes. The conjugated probes are particles modified with a binding member that is configured to bind with a norovirus. The particles also have a fluorescent label. A general method of detecting the virus includes (i) preparing a sample with contaminants, (ii) processing the sample and depositing it onto the assay device, and (iii) measuring the fluorescence signal.
    Type: Application
    Filed: November 27, 2014
    Publication date: November 9, 2017
    Inventors: Bao Trong Do, Jonathan Hofmekler, Cesar A. Morales, David W. Koenig, Yang Huang, Aimin He
  • Patent number: 9434977
    Abstract: There is provided a lateral flow assay that can provide an indication of Gram negative (GN) or Gram positive (GP) infection (or both) within 30 minutes, and desirably in less than 15 minutes. The immediate result would signal the presence of Gram negative bacteria, Gram positive bacteria, both Gram negative and Gram positive bacteria, or no bacteria detected. The detection level would be above a specific bacterial concentration threshold that is clinically significant infection source (e.g. 10^3 cfu/ml) versus the presence of a colonizing bacteria that is not a part of the active infection.
    Type: Grant
    Filed: February 27, 2013
    Date of Patent: September 6, 2016
    Assignee: Avent, Inc.
    Inventors: James M. Takeuchi, Adrienne A. Hershey, Scott M. Teixeira, Stephanie M. Martin, Juan Pablo Aragon, Cindy C. Korir-Morrison, Jonathan Hofmekler
  • Patent number: 9226502
    Abstract: A fibrous web that includes a cationic polymer that contains a cationic monomer comprising a cationic functional group having an affinity for the negatively charged cell walls of bacteria and a hydrophobic monomer comprising a hydrophobic functional group is provided. The molar ratio of the cationic monomer to the hydrophobic monomer is greater than about 1:1. The affinity of the cationic polymer for the bacteria allows the web to capture bacteria, thereby removing them from a surface or liquid, without the use of harsh chemicals, and also inhibiting their spread to other surfaces and liquids that may contact the web.
    Type: Grant
    Filed: March 31, 2014
    Date of Patent: January 5, 2016
    Assignee: Kimberly-Clark Worldwide, Inc.
    Inventors: Cindy Korir-Morrison, Jonathan Hofmekler, Cesar Z. Morales, David William Koenig, Bao Trong Do
  • Publication number: 20150272117
    Abstract: A fibrous web that includes a cationic polymer that contains a cationic monomer comprising a cationic functional group having an affinity for the negatively charged cell walls of bacteria and a hydrophobic monomer comprising a hydrophobic functional group is provided. The molar ratio of the cationic monomer to the hydrophobic monomer is greater than about 1:1. The affinity of the cationic polymer for the bacteria allows the web to capture bacteria, thereby removing them from a surface or liquid, without the use of harsh chemicals, and also inhibiting their spread to other surfaces and liquids that may contact the web.
    Type: Application
    Filed: March 31, 2014
    Publication date: October 1, 2015
    Applicant: Kimberly-Clark Worldwide, Inc.
    Inventors: Cindy Korir-Morrison, Jonathan Hofmekler, Cesar Z. Morales, David William Koenig, Bao Trong Do
  • Publication number: 20140242613
    Abstract: There is provided a lateral flow assay that can provide an indication of Gram negative (GN) or Gram positive (GP) infection (or both) within 30 minutes, and desirably in less than 15 minutes. The immediate result would signal the presence of Gram negative bacteria, Gram positive bacteria, both Gram negative and Gram positive bacteria, or no bacteria detected. The detection level would be above a specific bacterial concentration threshold that is clinically significant infection source (e.g. 10?3 cfu/ml) versus the presence of a colonizing bacteria that is not a part of the active infection.
    Type: Application
    Filed: February 27, 2013
    Publication date: August 28, 2014
    Applicant: KIMBERLY-CLARK WORLDWIDE, INC.
    Inventors: James M. Takeuchi, Adrienne A. Hershey, Scott M. Teixeira, Stephanie M. Martin, Juan Pablo Aragon, Cindy C. Korir-Morrison, Jonathan Hofmekler