Patents by Inventor Jonathan L. Rolfe
Jonathan L. Rolfe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8371296Abstract: Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. Precise delivery of nitric oxide at therapeutic levels of 20 to 100 ppm and inhibition of reaction of nitric oxide with oxygen to form toxic impurities such as nitrogen dioxide can provide effective inhalation therapy for pulmonary hypertension.Type: GrantFiled: May 8, 2006Date of Patent: February 12, 2013Assignee: Geno, LLCInventors: David H. Fine, Stephen J. MacDonald, David Rounbehler, David Wheeler, Jonathan L. Rolfe, George Jarvis
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Patent number: 8221800Abstract: Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. Precise delivery of nitric oxide at therapeutic levels of 20 to 100 ppm and inhibition of reaction of nitric oxide with oxygen to form toxic impurities such as nitrogen dioxide can provide effective inhalation therapy for pulmonary hypertension.Type: GrantFiled: April 7, 2006Date of Patent: July 17, 2012Assignee: Geno LLCInventors: David H. Fine, Stephen J. MacDonald, David R. Rounbehler, David Wheeler, Jonathan L. Rolfe, George Jarvis
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Patent number: 8066904Abstract: Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. Precise delivery of nitric oxide at therapeutic levels of 20 to 100 ppm and inhibition of reaction of nitric oxide with oxygen to form toxic impurities such as nitrogen dioxide can provide effective inhalation therapy for pulmonary hypertension.Type: GrantFiled: August 28, 2002Date of Patent: November 29, 2011Assignee: Geno LLCInventors: David H. Fine, Stephen J. MacDonald, David Rounbehler, David Wheeler, Jonathan L. Rolfe, George Jarvis
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Patent number: 7208222Abstract: A porous structure having a plurality of bonded sheets each sheet having at least one aperture that partially overlaps an aperture of at least one other sheet. A method of producing a porous structure including stacking a plurality of sheets each sheet having a multiplicity of apertures, and bonding each sheet to its adjoining sheet. An open-pore network structure having a multiplicity of sheets each having a repeatable pattern. At least a portion of each sheet is bonded to the web of an adjacent sheet. The porous area of at least one of the sheets is askew to the porous area of at least another of the sheets. An open-pore structure having a multiplicity of bonded sheets, each sheet having a repeatable pattern defining a multiplicity of perforations, and a plurality of apertures defined by the repeatable pattern, the apertures extending through the perforations of at least two adjacent plates.Type: GrantFiled: July 23, 2004Date of Patent: April 24, 2007Assignee: Viasys Healthcare Inc.Inventors: Jonathan L. Rolfe, Mark P. Amrich, Joseph A. Buturlia, Robert Cairns, Robert Lynch, Michael Gerry
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Patent number: 7052671Abstract: A composition comprising a carrier liquid; a dispersant; and a chemical hydride. The composition can be used in a hydrogen generator to generate hydrogen for use, e.g., as a fuel. A regenerator recovers elemental metal from byproducts of the hydrogen generation process.Type: GrantFiled: January 11, 2002Date of Patent: May 30, 2006Assignee: Safe Hydrogen, LLCInventors: Andrew W. McClaine, Jonathan L. Rolfe, Christopher A. Larsen, Ravi K. Konduri
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Patent number: 7040313Abstract: Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. Precise delivery of nitric oxide at therapeutic levels of 20 to 100 ppm and inhibition of reaction of nitric oxide with oxygen to form toxic impurities such as nitrogen dioxide can provide effective inhalation therapy for pulmonary hypertension.Type: GrantFiled: August 28, 2002Date of Patent: May 9, 2006Assignee: CyTerra CorporationInventors: David H. Fine, Stephen J. MacDonald, David Rounbehler, David Wheeler, Jonathan L. Rolfe, George Jarvis
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Patent number: 7025869Abstract: Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. Precise delivery of nitric oxide at therapeutic levels of 20 to 100 ppm and inhibition of reaction of nitric oxide with oxygen to form toxic impurities such as nitrogen dioxide can provide effective inhalation therapy for pulmonary hypertension.Type: GrantFiled: August 28, 2002Date of Patent: April 11, 2006Assignee: CyTerra CorporationInventors: David H. Fine, Stephen J. MacDonald, David Rounbehler, David Wheeler, Jonathan L. Rolfe, George Jarvis
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Patent number: 7018418Abstract: Textured surface having micro recesses such that the outer surface overhangs the micro recesses. Embodiments of the textured surface include sharp edges for promoting bone deposition and growth within the micro recesses, protrusions of varying depth from the surface that include overhangs, and micro recesses that are at least partially defined by complex ellipsoids.Type: GrantFiled: July 24, 2002Date of Patent: March 28, 2006Assignee: Tecomet, Inc.Inventors: Mark Amrich, Jonathan L. Rolfe, Joseph Buturlia, Robert F. Lynch
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Publication number: 20030194869Abstract: Method for producing a multiplicity of undercut micro recesses in a surface of an article, such that the article exhibits a greater fractal area at a level below the surface than is exhibited at the surface. The method comprises applying a maskant layer to a selected surface of the article, removing the maskant layer in selected loci to expose underlying portions of the article surface in a selected pattern, applying an etchant to the exposed underlying surface portions for a time sufficient to etch the exposed portions of the article and to enable the etchant to etch beneath portions of the remaining maskant layer, and removing the remaining maskant layer to provide the surface in exposed condition with the multiplicity of undercut recesses, to provide an engineered pattern of the recesses.Type: ApplicationFiled: April 22, 2003Publication date: October 16, 2003Inventors: Mark P. Amrich, Joseph Buturlia, Robert F. Lynch, Jonathan L. Rolfe
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Patent number: 6599322Abstract: A surgical implant having a datum surface for engaging tissue. Embodiments of the surgical implant include a recess in an original datum surface having a sharp undercut ovoid configuration and a multiplicity of recesses that are interconnected.Type: GrantFiled: October 12, 2001Date of Patent: July 29, 2003Assignee: Tecomet, Inc.Inventors: Mark P. Amrich, Joseph Buturlia, Robert F. Lynch, Jonathan L. Rolfe
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Publication number: 20030065401Abstract: Textured surface having micro recesses such that the outer surface overhangs the micro recesses. Embodiments of the textured surface include sharp edges for promoting bone deposition and growth within the micro recesses, protrusions of varying depth from the surface that include overhangs, and micro recesses that are at least partially defined by complex ellipsoids.Type: ApplicationFiled: July 24, 2002Publication date: April 3, 2003Inventors: Mark Amrich, Jonathan L. Rolfe, Joseph Buturlia, Robert F. Lynch
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Publication number: 20030064115Abstract: Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. Precise delivery of nitric oxide at therapeutic levels of 20 to 100 ppm and inhibition of reaction of nitric oxide with oxygen to form toxic impurities such as nitrogen dioxide can provide effective inhalation therapy for pulmonary hypertension.Type: ApplicationFiled: August 28, 2002Publication date: April 3, 2003Inventors: David H. Fine, Stephen J. MacDonald, David Rounbehler, David Wheeler, Jonathan L. Rolfe, George Jarvis
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Publication number: 20030062043Abstract: Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. Precise delivery of nitric oxide at therapeutic levels of 20 to 100 ppm and inhibition of reaction of nitric oxide with oxygen to form toxic impurities such as nitrogen dioxide can provide effective inhalation therapy for pulmonary hypertension.Type: ApplicationFiled: August 28, 2002Publication date: April 3, 2003Inventors: David H. Fine, Stephen J. MacDonald, David Rounbehler, David Wheeler, Jonathan L. Rolfe, George Jarvis
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Publication number: 20030064028Abstract: Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. Precise delivery of nitric oxide at therapeutic levels of 20 to 100 ppm and inhibition of reaction of nitric oxide with oxygen to form toxic impurities such as nitrogen dioxide can provide effective inhalation therapy for pulmonary hypertension.Type: ApplicationFiled: August 28, 2002Publication date: April 3, 2003Inventors: David H. Fine, Stephen J. MacDonald, David Rounbehler, David Wheeler, Jonathan L. Rolfe, George Jarvis
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Publication number: 20020166286Abstract: A composition comprising a carrier liquid; a dispersant; and a chemical hydride. The composition can be used in a hydrogen generator to generate hydrogen for use, e.g., as a fuel. A regenerator recovers elemental metal from byproducts of the hydrogen generation process.Type: ApplicationFiled: January 11, 2002Publication date: November 14, 2002Inventors: Andrew W. McClaine, Jonathan L. Rolfe, Christopher A. Larsen, Ravi K. Konduri
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Patent number: 6050990Abstract: Methods of applying laser light to the skin, and apparatus therefor, include methods for removing hair, for synchronizing hair growth, for stimulating hair growth, for treating Herpes virus, for reducing sweat and body odor, for in situ formation of a chromophore in hair ducts, for reducing light loss at the skin surface, for grafting of hair stem cells, and for removing keloid or hypertrophic scars. The hair removal methods include controlling the proportions of photomechanical and photothermal damage by selection of laser parameters, chromophore particle size and/or pulse duration, with optional dynamic skin cooling. Additional hair removal methods include infiltrating a photoactivated drug into hair ducts and exposing the skin to sunlight or administering an anti-proliferative agent into hair ducts, for example, by encapsulating the anti-proliferative agent in a slow release vehicle.Type: GrantFiled: December 4, 1997Date of Patent: April 18, 2000Assignee: ThermoLase CorporationInventors: Nikolai I. Tankovich, Kurt A. Dasse, David H. Fine, Paul W. Fairchild, Zhong-Quan Zhao, Mike Lefebvre, John Lee, Jr., Jonathan L. Rolfe, Susan Murrell, Allen Hunter, II, Amanda J Reynolds, Vladimir G. Kolinko
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Patent number: 5209786Abstract: Disclosed are integrity-enhanced thermoelectric devices and methods of their preparation. Such devices have the following characteristics: (1) there is, on average, no greater than about 10% incidence of function loss (failure) of the device on application to the device of a substantial impact or distortion force or corrosion exposure, and (2) the device have at least about 85% of the thermal performance of thermoelectric devices without integrity enhancement (i.e., thermal conductivity across the integrity-enhanced devices is significantly less than 0.0021 Cal-Cm/Cm.sup.2 Sec .degree.C., and is less than or equal to about 0.0015 Cal-Cm/Cm.sup.2 Sec .degree.C.; empirically expressed as maintenance of at least a 40.degree. C. temperature differential over the intra-plate distance which is about 3/16 to about 1/4 of an inch.).Type: GrantFiled: October 9, 1990Date of Patent: May 11, 1993Assignee: Thermo Electron Technologies CorporationInventors: Jonathan L. Rolfe, John S. Beaty
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Patent number: 5194128Abstract: A method for the manufacture of ultrafine particles or atom clusters is disclosed. The ultrafine particles of size between about 10 to 1000 Angstroms are formed by the disruption of the crystal lattice or micrograin structure of the metal, alloy or intermetallic compound in one or both of two spaced electrodes by a high frequency, high voltage, high peak current discharge. The ultrafine particles are not subjected to fractionation as in evaporative processes and accordingly are remarkably predictable in both particle size, distribution of sizes and atomic composition, and also are readily transportable in carrier gases.Type: GrantFiled: August 2, 1991Date of Patent: March 16, 1993Assignee: Thermo Electron Technologies CorporationInventors: John S. Beaty, Jonathan L. Rolfe
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Patent number: 5062936Abstract: A method for the manufacture of ultrafine particles or atom clusters is disclosed. The ultrafine particles of size between about 10 to 1000 Angstroms are formed by the disruption of the crystal lattice or micrograin structure of the metal, alloy or intermetallic compound in one or both of two spaced electrodes by a high frequency, high voltage, high peak current discharge. The ultrafine particles are not subjected to fractionation as in evaporative processes and accordingly are remarkably predictable in both particle size, distribution of sizes and atomic composition, and also are readily transportable in carrier gases.Type: GrantFiled: July 12, 1989Date of Patent: November 5, 1991Assignee: Thermo Electron Technologies CorporationInventors: John S. Beaty, Jonathan L. Rolfe
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Patent number: 4880690Abstract: A perfume patch comprising a fragrance-emitting member having a fragrance dispersed within an ultra-thin polyurethane membrane. A layer of pressure sensitive adhesive is applied to adhere the member to a surface. The polyurethane is formed from a diisocyanate, a macroglycol, and an acrylyl chain terminator to which a photoinitiator and a fragrance oil are added prior to curing. A barrier layer may be applied by an adhesive or other suitable means to prevent migration of the fragrance oil to the adhesive so that no residue of adhesive remains on the surface. The perfume patch preferably includes a support for the fragrance-emitting member for ease in application and handling.Type: GrantFiled: September 9, 1988Date of Patent: November 14, 1989Assignee: Thermedics, Inc.Inventors: Michael Szycher, Jonathan L. Rolfe