Abstract: The present invention facilitates semiconductor cooling by combining a semiconductor die and a thermoelectric cooler into a single, integrated package or system. The thermoelectric cooler is controllably operated so as to dissipate thermal energy generated by the semiconductor die. Active thermal management of the package is performed by a controller, which monitors temperature(s) of the semiconductor die and increases or adjusts cooling such that desired performance levels can be obtained. The invention can also thermally manage one or more regions of a semiconductor die and can thermally manage a plurality of semiconductor dies.