Abstract: Medical devices, such as stents, and methods of the devices are described.

Abstract: A radially expandable stent and methods of making the same, the stent made entirely of a bioabsorbable metal, the stent having a portion of increased radiopacity, wherein the portion of increased radiopacity has one or more of the following characteristics: i. the wall thickness of the stent in the portion of increased radiopacity exceeds the wall thickness of the wall immediately adjacent thereto by at least 0.0010?; ii. the width of the stent in the portion of increased radiopacity exceeds the width of the stent immediately adjacent thereto by at least 0.0005?.

Abstract: A medical implant includes a metallic base, a tie layer, and at least a first layer overlying an outer surface of the tie layer. The tie layer is bonded to at least a portion of a surface of the metallic base. The tie layer includes magnesium or a magnesium-based alloy. The tie layer can have an outer surface comprising dendritic grains. The tie layer can have a rough outer surface defined by pores, projecting grain structures, and/or projecting particles. A method of producing a tie layer on a medical device includes applying magnesium or a magnesium-based alloy to the medical device and cooling the magnesium or the magnesium-based alloy to produce a rough outer surface.

Abstract: Medical devices, such as stents, and methods of the devices are described.

Abstract: The invention relates to a stent-graft with a bioabsorbable structure and a permanent graft for luminal support and ‘treatment of arterial fistulas, occlusive disease, and aneurysms. The bioabsorbable structure is formed from braided filaments of materials such as PLA, PLLA, PDLA, and PGA and the graft is formed from materials such as PET, ePTFE, PCU or PU.

Abstract: A platinum enhanced radiopaque alloy particularly suitable for manufacture of implantable and/or intravascular medical devices. A stent is one preferred medical device which is a generally tubular structure that is expandable upon implantation in a vessel lumen to maintain flow therethrough. The stent is formed from the alloy which has improved radiopacity relative to present utilized stainless steel alloys. This alloy preferably contains from about 2 wt. % to about 50 wt. % platinum; from about 11 wt. % to about 18 wt. % chromium; about 5 wt. % to about 12 wt. % nickel and at least about 15 wt. % iron.

Abstract: The invention relates to a stent-graft with a bioabsorbable structure and a permanent graft for luminal support and treatment of arterial fistulas, occlusive disease, and aneurysms. The bioabsorbable structure is formed from braided filaments of materials such as PLA, PLLA, PDLA, and PGA and the graft is formed from materials such as PET, ePTFE, PCU or PU.

Abstract: Embodiments of the present invention relate to medical devices that provide signals to diagnostic equipment such that functionality of an implantable member can be determined. In particular, various designs and structures are utilized to signal tissue growth on an implantable member such as a stent. The tissue growth can limit flow through the stented lumen. If the growth has a thickness above a certain limit, a signal can be detected by diagnostic equipment such that a proper diagnosis can be made.

Abstract: An implantable medical device includes a bioerodible portion adapted to erode when exposed to a physiological environment. The bioerodible portion includes an alloy comprising at least 10 weight percent chromium and has an outer surface having a ratio of chromium oxide to chromium metal of less than 5. The bioerodible implantable medical device can be created by implanting metallic ions into an alloy including at least 10 weight percent chromium to define an outer surface of a medical implant, or precursor thereof.

Abstract: An endoprosthesis includes an expandable tubular body defined by a plurality of struts. In some embodiments, the expandable tubular body includes a bioerodible metal that has at least a first surface region and a second surface region. The first and second surface regions can have different surface oxide compositions. In some embodiments, the first portion has a thermally altered microstructure and the second portion has a wrought microstructure. The thermally altered microstructure can be a cast microstructure comprising dendritic grains. The first portion forms at least a portion of an outer surface of the expandable tubular body. In some embodiments, the expandable tubular body includes iron or a bioerodible iron alloy and at least one surface of the expandable tubular body includes a substantially uniform coating of iron(III) oxide.

Abstract: Endoprostheses such as stents are disclosed that are, or that include portions that are, bioerodible.

Abstract: Medical devices, for example, implantable devices such as endoprostheses, include a composite material having a polymer.

Abstract: An endoprosthesis that includes a composite having a metal matrix and a plurality of stiffening particles in the matrix. The metal of the metal matrix can include titanium, niobium, tantalum, or alloys thereof. The stiffening particles can include a metal core and a thin surface layer. The thin surface layer can include oxides, carbides, nitrides, or combinations thereof.

Abstract: Medical devices, such as stents, and methods of making the devices are disclosed. In some embodiments, a medical device includes an alloy having tantalum, tungsten, zirconium and niobium. For example, the alloy can include from about 20% to about 40% by weight of tantalum, from about 0.5% to about 9% by weight of tungsten, and from about 0.5% to about 10% by weight of zirconium.

Abstract: A medical implant includes a bioerodible portion adapted to degrade under physiological conditions. The bioerodible portion includes a bioerodible metal matrix and a salt or clay within the bioerodible metal matrix.

Abstract: Medical devices, such as endoprostheses, and methods of making the devices are disclosed. In some embodiments, an endoprosthesis includes a first portion having a first width, and a second portion having a second width different than the first width, wherein the first and second portions have different grain sizes.

Abstract: Medical devices, such as stents, and methods of making the devices are disclosed. In some embodiments, a medical device includes an alloy having tantalum, tungsten, zirconium and niobium. For example, the alloy can include from about 20% to about 40% by weight of tantalum, from about 0.5% to about 9% by weight of tungsten, and from about 0.5% to about 10% by weight of zirconium.

Abstract: Medical devices, such as stents, and methods of the devices are described.

Abstract: Medical devices, such as endoprostheses, and methods of making the devices are disclosed. The endoprostheses comprise a tubular member capable of maintaining patency of a bodily vessel. The tubular member includes a mixture of at least two compositions, where the presence of the second composition gives the mixture a greater hardness than that of the first composition alone. The first composition includes less than about 25 weight percent chromium, less than about 7 weight percent molybdenum, from about 10 to about 35 weight percent nickel, and iron. The second composition is different from the first and is present from about 0.1 weight percent to about 5 weight percent of the mixture.

Abstract: Medical devices, such as stents, stent-grafts, grafts, guidewires, and filters, having enhanced radiopacity are disclosed.