Patents by Inventor Jonathan Trent

Jonathan Trent has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10542923
    Abstract: A system and urine sensing devices for and method of monitoring kidney function is disclosed, wherein the system and method can be used for the early detection of acute kidney injury (AKI). Namely, a kidney function monitoring system provides a portable urine monitor system that can provide real-time and continuous feedback about urine output and/or level of at least one urinary component (e.g., sodium). The kidney function monitoring system further comprises at least one urine sensing device, wherein the urine sensing device comprises a digital weight scale, a stand onto which a urine collection vessel can be positioned, and an interface between the digital weight scale and the stand that transfers the force of the stand and contents of the urine collection vessel to the digital weight scale. Further, the portable monitoring device comprises an adaptive and modular self-learning algorithm for the real-time assessment of AKI risk.
    Type: Grant
    Filed: April 15, 2016
    Date of Patent: January 28, 2020
    Assignee: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Aaron Chang, Sriram Chadalavada, Madeleine Clegg, Patience Osei, Alexandra Sibole, Nevin Katz, Jonathan Trent Magruder
  • Publication number: 20180110455
    Abstract: A system and urine sensing devices for and method of monitoring kidney function is disclosed, wherein acute kidney injury (AKI). Namely, a kidney function monitoring system provides a portable urine monitor system that can provide real-time and continuous feedback about urine output and/or level of at least one urinary component (e.g., sodium). The kidney function monitoring system further comprises at least one urine sensing device, wherein the urine sensing device comprises a digital weight scale, a stand onto which a urine collection vessel can be positioned, and an interface between the digital weight scale and the stand that transfers the force of the stand and contents of the urine collection vessel to the digital weight scale. Further, the portable monitoring device comprises an adaptive and modular self-learning algorithm for the real-time assessment of AKI risk.
    Type: Application
    Filed: April 15, 2016
    Publication date: April 26, 2018
    Applicant: THE JOHNS HOPKINS UNIVERSITY
    Inventors: AARON CHANG, SRIRAM CHADALAVADA, MADELEINE CLEGG, PATIENCE OSEI, ALEXANDRA SIBOLE, NEVIN KATZ, JONATHAN TRENT MAGRUDER
  • Publication number: 20150064736
    Abstract: Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated from the environment using PCR methods are described.
    Type: Application
    Filed: September 11, 2014
    Publication date: March 5, 2015
    Applicant: DANISCO US INC.
    Inventors: Mark Donnelly, William H. Eschenfeldt, Jonathan Trent
  • Publication number: 20140141448
    Abstract: Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated from the environment using PCR methods are described.
    Type: Application
    Filed: October 31, 2013
    Publication date: May 22, 2014
    Applicant: Danisco US Inc.
    Inventors: Mark Donnelly, William H. Eschenfeldt, Jonathan Trent
  • Patent number: 8597901
    Abstract: Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated from the environment using PCR methods are described.
    Type: Grant
    Filed: June 15, 2012
    Date of Patent: December 3, 2013
    Assignee: Danisco US Inc.
    Inventors: Mark Donnelly, William H. Eschenfeldt, Jonathan Trent
  • Publication number: 20120322095
    Abstract: Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated from the environment using PCR methods are described.
    Type: Application
    Filed: June 15, 2012
    Publication date: December 20, 2012
    Applicant: DANISCO US INC.
    Inventors: MARK DONNELLY, WILLIAM H. ESCHENFELDT, JONATHAN TRENT
  • Patent number: 8216811
    Abstract: Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated from the environment using PCR methods are described.
    Type: Grant
    Filed: March 4, 2011
    Date of Patent: July 10, 2012
    Assignee: Danisco US Inc.
    Inventors: Mark Donnelly, William H. Eschenfeldt, Jonathan Trent
  • Publication number: 20110229943
    Abstract: Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated from the environment using PCR methods are described.
    Type: Application
    Filed: March 4, 2011
    Publication date: September 22, 2011
    Applicant: DANISCO US INC.
    Inventors: MARK DONNELLY, WILLIAM H. ESCHENFELDT, JONATHAN TRENT
  • Patent number: 7922483
    Abstract: Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated from the environment using PCR methods are described.
    Type: Grant
    Filed: June 18, 2009
    Date of Patent: April 12, 2011
    Assignee: Danisco US Inc.
    Inventors: Mark Donnelly, William H. Eschenfeldt, Jonathan Trent
  • Publication number: 20100021908
    Abstract: Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated from the environment using PCR methods are described.
    Type: Application
    Filed: June 18, 2009
    Publication date: January 28, 2010
    Inventors: MARK DONNELLY, WILLIAM H. ESCHENFELDT, JONATHAN TRENT
  • Patent number: 7563609
    Abstract: Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated from the environment using PCR methods are described.
    Type: Grant
    Filed: March 18, 2008
    Date of Patent: July 21, 2009
    Assignee: Genencor International, Inc.
    Inventors: Mark Donnelly, William H. Eschenfeldt, Jonathan Trent
  • Publication number: 20080248546
    Abstract: Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated from the environment using PCR methods are described.
    Type: Application
    Filed: March 18, 2008
    Publication date: October 9, 2008
    Inventors: Mark Donnelly, William H. Eschenfeldt, Jonathan Trent
  • Patent number: 7374917
    Abstract: Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated from the environment using PCR methods are described.
    Type: Grant
    Filed: December 17, 2004
    Date of Patent: May 20, 2008
    Assignee: Genencor International, Inc.
    Inventors: Mark Donnelly, William H. Eschenfeldt, Jonathan Trent
  • Publication number: 20060084792
    Abstract: The present invention provides chaperonin polypeptides which are modified to include N-terminal and C-terminal ends that are relocated from the central pore region to various different positions in the polypeptide which are located on the exterior of the folded modified chaperonin polypeptide. In the modified chaperonin polypeptide, the naturally-occurring N-terminal and C-terminal ends are joined together directly or with an intervening linker peptide sequence. The relocated N-terminal or C-terminal ends can be covalently joined to, or bound with another molecule such as a nucleic acid molecule, a lipid, a carbohydrate, a second polypeptide, or a nanoparticle. The modified chaperonin polypeptides can assemble into double-ringed chaperonin structures. Further, the chaperonin structures can organize into higher order structures such as nanofilaments or nanoarrays which can be used to produce nanodevices and nanocoatings.
    Type: Application
    Filed: August 1, 2005
    Publication date: April 20, 2006
    Inventors: Chad Paavola, Jonathan Trent, Suzanne Chan, Yi-Fen Li, R. McMillan, Hiromi Kagawa
  • Publication number: 20050158762
    Abstract: Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated from the environment using PCR methods are described.
    Type: Application
    Filed: December 17, 2004
    Publication date: July 21, 2005
    Inventors: Mark Donnelly, William Eschenfeldt, Jonathan Trent
  • Publication number: 20050130258
    Abstract: The following application relates to nanotemplates, nanostructures, nanoarrays and nanodevices formed from wild-type and mutated chaperonin polypeptides, methods of producing such compositions, methods of using such compositions and particular chaperonin polypeptides that can be utilized in producing such compositions.
    Type: Application
    Filed: November 8, 2002
    Publication date: June 16, 2005
    Inventors: Jonathan Trent, R. McMillan, Hiromi Kagawa, Chad Paavola
  • Patent number: 6864075
    Abstract: Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated from the environment using PCR methods are described.
    Type: Grant
    Filed: April 17, 2003
    Date of Patent: March 8, 2005
    Assignee: Genencor International, Inc.
    Inventors: Mark Donnelly, William H. Eschenfeldt, Jonathan Trent
  • Publication number: 20030203449
    Abstract: Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated from the environment using PCR methods are described.
    Type: Application
    Filed: April 17, 2003
    Publication date: October 30, 2003
    Inventors: Mark Donnelly, William H. Eschenfeldt, Jonathan Trent
  • Patent number: 6576452
    Abstract: Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated from the environment using PCR methods are described.
    Type: Grant
    Filed: October 4, 2000
    Date of Patent: June 10, 2003
    Assignee: Genencor International, Inc.
    Inventors: Mark Donnelly, William H. Eschenfeldt, Jonathan Trent
  • Publication number: 20020100737
    Abstract: A rack assembly for mounting telecommunications equipment is provided which utilizes at least one but preferably two upstanding spaced-apart frame members that have at least one but preferably both front and back flanges hemmed in order to provide improved structural stiffness to the rack as well as enhanced distance between the upstanding frame members for mounting digital telecommunications equipment and the like therebetween.
    Type: Application
    Filed: February 1, 2001
    Publication date: August 1, 2002
    Inventors: Jonathan Trent Walter, Gilbert Walden Reece, Bryan Chesley Caudill