Patents by Inventor Jonathan Yee-Ting Flsu

Jonathan Yee-Ting Flsu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYSTEMS AND METHODS FOR PREDICTING REPAIR OUTCOMES IN GENETIC ENGINEERING
    Publication number: 20220238182
    Abstract: The specification provides methods for introducing a desired genetic change in a nucleotide sequence using a double-strand break (DSB)-inducing genome editing system, the method comprising: identifying one or more available cut sites in a nucleotide sequence; analyzing the nucleotide sequence and available cut sites with a computational model to identify the optimal cut site for introducing the desired genetic change into the nucleotide sequence; and contacting the nucleotide sequence with a DSB-inducing genome editing system, thereby introducing the desired genetic change in the nucleotide sequence at the cut site.
    Type: Application
    Filed: December 15, 2018
    Publication date: July 28, 2022
    Applicants: The Broad Institute, Inc., Massachusetts Institute of Technology, The Brigham and Women's Hospital, Inc., President and Fellows of Harvard College
    Inventors: Max Walt Shen, Jonathan Yee-Ting Flsu, Mandana Arbab, David K. Gifford, David R. Liu, Richard Irving Sherwood