Patents by Inventor Jong Hoon Hahn
Jong Hoon Hahn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 9017941Abstract: A method for nucleic acid analysis including injecting a slight amount of nucleic acid sample for analysis, characterized in that most of a nucleic acid sample which is not used, excluding the slight amount of the nucleic acid sample which is used for analysis, can be obtained as a pure product which is not contaminated with a fluorescent material, and a microchip for analyzing nucleic acid which enables such method for nucleic acid analysis, are provided. The method for nucleic acid analysis may analyze at least two different nucleic acid samples in a continuous manner by sequentially injecting the at least two different nucleic acid samples.Type: GrantFiled: March 7, 2013Date of Patent: April 28, 2015Assignee: Postech Academy-Industry FoundationInventors: Jong Hoon Hahn, Byoung Joo Kwak, Han-Ok Kim
-
Publication number: 20130341189Abstract: A method for nucleic acid analysis including injecting a slight amount of nucleic acid sample for analysis, characterized in that most of a nucleic acid sample which is not used, excluding the slight amount of the nucleic acid sample which is used for analysis, can be obtained as a pure product which is not contaminated with a fluorescent material, and a microchip for analyzing nucleic acid which enables such method for nucleic acid analysis, are provided. The method for nucleic acid analysis may analyze at least two different nucleic acid samples in a continuous manner by sequentially injecting the at least two different nucleic acid samples.Type: ApplicationFiled: March 7, 2013Publication date: December 26, 2013Applicant: POSTECH ACADEMY-INDUSTRY FOUNDATIONInventors: JONG HOON HAHN, BYOUNG JOO KWAK, HAN-OK KIM
-
Patent number: 8182864Abstract: The present invention provides a method for modification of microchannels of a polydimethylsiloxane (PDMS) microchip, which includes the steps of: a) mixing an alkoxysilane precursor, an alkyl alkoxysilane precursor, and a solvent to prepare a sol-gel solution; b) oxidizing microchannels of the PDMS microchip; and c) coating the oxidized microchannels with the sol-gel solution prepared in step a). The PDMS microchip modified according to the method of the present invention shows higher hydrophilicity than an unmodified PDMS microchip. And, when the modified PDMS channels are filled with an organic solvent, channel swelling can be reduced, and thus various organic solvents can be used for the modified PDMS microchip compared to an unmodified PDMS microchip. Further, it can be widely applied for various fields because absorptivity of non-polar substances can be reduced.Type: GrantFiled: August 13, 2008Date of Patent: May 22, 2012Assignees: Postech Academy-Industry Foundaction, POSCOInventors: Jong-Hoon Hahn, Jin Hee Park, Miok Shin
-
Publication number: 20110177563Abstract: A high-throughput device is structured to perform a continuous-flow reaction, e.g., a polymerase chain reaction (PCR) requiring repetitive temperature control in a timely fashion.Type: ApplicationFiled: February 11, 2011Publication date: July 21, 2011Applicants: POSTECH FOUNDATION, BIONEER CORPORATIONInventors: Jong Hoon HAHN, Nokyoung PARK, Kwanseop LIM
-
Publication number: 20090117287Abstract: The present invention provides a method for modification of microchannels of a polydimethylsiloxane (PDMS) microchip, which includes the steps of: a) mixing an alkoxysilane precursor, an alkyl alkoxysilane precursor, and a solvent to prepare a sol-gel solution; b) oxidizing microchannels of the PDMS microchip; and c) coating the oxidized microchannels with the sol-gel solution prepared in step a). The PDMS microchip modified according to the method of the present invention shows higher hydrophilicity than an unmodified PDMS microchip. And, when the modified PDMS channels are filled with an organic solvent, channel swelling can be reduced, and thus various organic solvents can be used for the modified PDMS microchip compared to an unmodified PDMS microchip. Further, it can be widely applied for various fields because absorptivity of non-polar substances can be reduced.Type: ApplicationFiled: August 13, 2008Publication date: May 7, 2009Applicants: POSTECH ACADEMY-INDUSTRY FOUNDATION, POSCOInventors: Jong-Hoon Hahn, Jin Hee Park, Miok Shin
-
Publication number: 20080145923Abstract: A high-throughput device is structured to perform a continuous-flow reaction, e.g., a polymerase chain reaction (PCR) requiring repetitive temperature control in a timely fashion.Type: ApplicationFiled: February 3, 2004Publication date: June 19, 2008Inventors: Jong Hoon Hahn, Nokyoung Park, Kwanseop Lim
-
Patent number: 7157053Abstract: A high-efficiency, high-sensitivity absorbance detection system in a lab-on-a-chip is provided. The absorbance detection system includes detection cells having an optical pathlength ten times and/or much longer than the width of a separation channel to improve detection sensitivity, lens structures for collimating light in the detection cells, and slit structures for preventing scattered light from entering detectors. The detection cells, the lens structures, and the slit structures of the absorbance detection system are fabricated and integrated in a lab-on-a-chip. The absorbance detection system exhibits excellent absorption efficiency, detection limit, and linearity, compared to existing absorbance detection systems, and can be applied for the detection of a variety of samples. The absorbance detection system does not need labeling of the samples which saves time and costs. The absorbance detection system can be used effectively in detecting trace compounds with a high sensitivity.Type: GrantFiled: July 18, 2002Date of Patent: January 2, 2007Assignee: Pohang University of Science and Technology FoundationInventors: Jong Hoon Hahn, Kyung Won Ro, Bong Chu Shim, Kwanseop Lim
-
Publication number: 20050266404Abstract: The present invention relates to a detection method of DNA hybridization comprising: (a) preparing a oligo-plate by fixing capture probes onto a working electrode surface, (b) hybridizing the capture probes with target probes, (c) reacting a nucleic acid binding material specific to single-stranded nucleic acid or a double-stranded nucleic acid, (d) thc nucleic acid binding material changes the charge state of the working electrode surface, and (e) measuring an electrochemical quantity depending on the charge state of the working electrode surface with an electrochemical method using an electroactive electrolytic condition.Type: ApplicationFiled: July 25, 2002Publication date: December 1, 2005Inventors: Jong-Hoon Hahn, Nkoyoung Park
-
Patent number: 6810713Abstract: Various kinds of fluid can be handled and delivered accurately in infinitesimal amounts through microchannels formed in an elastic polymeric substrate by periodically squeezing selective portions of the microchannel using a rotor to apply an external force on the elastic substrate. The delivery rate of the fluid is in the range from pL/sec to mL/sec determined by the rotation speed of the rotor which presses the microchannels and the dimensions of the microchannel. Regardless of physical properties of the fluid to be delivered, various kinds of fluids can be accurately delivered through the microchannels in the desired amount.Type: GrantFiled: July 16, 2002Date of Patent: November 2, 2004Assignee: LG. Electronics Inc.Inventors: Jong Hoon Hahn, Kwanscop Lim, Kihoon Na, Suhyeon Kim, Je-Kyun Park
-
Patent number: 6776864Abstract: A process, which comprises forming a metal micro-pattern on the surface of an inorganic substrate, surface-treating the surface of the metal micro-pattern and the surface of the plastic substrate to make it chemically reactive, and bringing the metal micro-pattern into contact with the surface of the plastic substrate to transfer the metal micro-pattern from the surface of the inorganic substrate to the surface of the plastic substrate, can be easily and simply carried out using conventional equipments to produce one or more metal pattern fixed on a plastic material.Type: GrantFiled: August 2, 2002Date of Patent: August 17, 2004Assignee: Postech FoundationInventors: Jong Hoon Hahn, Yong Min Park, Young Chan Kim, Bong Chu Shim
-
Publication number: 20030024632Abstract: A process, which comprises forming a metal micro-pattern on the surface of an inorganic substrate, surface-treating the surface of the metal micro-pattern and the surface of the plastic substrate to make it chemically reactive, and bringing the metal micro-pattern into contact with the surface of the plastic substrate to transfer the metal micro-pattern from the surface of the inorganic substrate to the surface of the plastic substrate, can be easily and simply carried out using conventional equipments to produce one or more metal pattern fixed on a plastic material.Type: ApplicationFiled: August 2, 2002Publication date: February 6, 2003Inventors: Jong Hoon Hahn, Yong Min Park, Young Chan Kim, Bong Chu Shim
-
Publication number: 20030026719Abstract: Various kinds of fluid can be handled and delivered accurately in infinitesimal amounts through microchannels formed in an elastic polymeric substrate by periodically squeezing selective portions of the microchannel using a rotor to apply an external force on the elastic substrate. The delivery rate of the fluid is in the range from pL/sec to mL/sec determined by the rotation speed of the rotor which presses the microchannels and the dimensions of the microchannel. Regardless of physical properties of the fluid to be delivered, various kinds of fluids can be accurately delivered through the microchannels in the desired amount.Type: ApplicationFiled: July 16, 2002Publication date: February 6, 2003Applicant: LG.Electronics Inc.Inventors: Jong Hoon Hahn, Kwanscop Lim, Kihoon Na, Suhyeon Kim, Je-Kyun Park
-
Publication number: 20030025129Abstract: Minute or infinitesimal amounts of fluid can be accurately delivered through microchannels formed in an elastic polymeric substrate. External (mechanical) force is applied on the substrate to progressively squeeze the microchannel along its length to push or pull the fluid through the microchannel. Fluids can be delivered at a constant rate and amount regardless of the kind of the fluid since fluid delivery is not affected by the physical properties of the fluid. The delivery rate of the fluid is determined in the ranges between femtoliters/sec and milliliters/sec by the size of the microchannel and the area of the substrate being pressed by the applied external (mechanical) force. Such techniques of fluid delivery can be applied to various fields including lab-on-a-chip technology, monitoring of chemical and biological processing, portable analyzing instruments, fine chemistry, clinical diagnosis and development of new medicines.Type: ApplicationFiled: June 21, 2002Publication date: February 6, 2003Applicant: LG.Electronics Inc.Inventors: Jong Hoon Hahn, Kwanseop Lim, Kihoon Na, Suhyeon Kim, Je-Kyun Park
-
Publication number: 20030017079Abstract: A high-efficiency, high-sensitivity absorbance detection system in a lab-on-a-chip is provided. The absorbance detection system includes detection cells having an optical pathlength ten times and/or much longer than the width of a separation channel to improve detection sensitivity, lens structures for collimating light in the detection cells, and slit structures for preventing scattered light from entering detectors. The detection cells, the lens structures, and the slit structures of the absorbance detection system are fabricated and integrated in a lab-on-a-chip. The absorbance detection system exhibits excellent absorption efficiency, detection limit, and linearity, compared to existing absorbance detection systems, and can be applied for the detection of a variety of samples. The absorbance detection system does not need labeling of the samples which saves time and costs. The absorbance detection system can be used effectively in detecting trace compounds with a high sensitivity.Type: ApplicationFiled: July 18, 2002Publication date: January 23, 2003Applicant: Pohang University of Science and Technology FoundationInventors: Jong Hoon Hahn, Kyung Won Ro, Bong Chu Shim, Kwanseop Lim
-
Publication number: 20030017077Abstract: Provided is a sample clean-up apparatus for removing low-molecular weight substances such as salts from high-molecular weight biological samples such as proteins by simple molecular diffusion in a laminar flow channel and enabling solvent exchange for samples to be suitable for mass spectrometry.Type: ApplicationFiled: July 16, 2002Publication date: January 23, 2003Applicant: Pohang University of Science and Technology FoundationInventors: Jong Hoon Hahn, Young Chan Kim, Kyung Won Ro, Nokyoung Park
-
Publication number: 20030012697Abstract: A microfluidic breadboard comprises a plurality of pairs of openings formed on an upper surface of a substrate and arranged at regular intervals, wherein each pair of openings are connected to each other through a microchannel formed in the bulk of the substrate so that the microfluidic breadboard has an array of U-shaped microchannels.Type: ApplicationFiled: July 16, 2002Publication date: January 16, 2003Inventors: Jong Hoon Hahn, Bong Chu Shim, Kyung Won Ro, Yong Min Park