Abstract: The present invention relates to a composition for preventing or treating transplantation rejection or a transplantation rejection disease, comprising a novel compound and a calcineurin inhibitor. A co-administration of the present invention 1) reduces the activity of pathogenic Th1 cells or Th17 cells, 2) increases the activity of Treg cells, 3) has an inhibitory effect against side effects, such as tissue damage, occurring in the sole administration thereof, 4) inhibits various pathogenic pathways, 5) inhibits the cell death of inflammatory cells, and 6) increases the activity of mitochondria, in an in vivo or in vitro allogenic model, a transplantation rejection disease model, a skin transplantation model, and a liver-transplanted patient, and thus inhibits transplantation rejection along with mitigating side effects possibly occurring in the administration of a conventional immunosuppressant alone.

Abstract: The present disclosure relates to a composition for antiobesity, which contains a Gynostemma pentaphyllum tea or a Gynostemma pentaphyllum tea extract as an active ingredient. The composition of the present disclosure, which contains a Gynostemma pentaphyllum tea or a Gynostemma pentaphyllum tea extract as an active ingredient, is effective for preventing, alleviating or treating diabetes, obesity, muscle loss, etc. since it exhibits the efficacy of increasing AMPK activity, promoting beta oxidation, promoting glucose uptake, etc. In addition, since the composition of the present disclosure is derived from a natural product, it can be safely used as a drug, food, etc. without side effects.

Abstract: A brake traction control system (BTCS) using a redundancy braking system includes a main braking force adjusting device configured to control a hydraulic brake of a vehicle, a sensor unit configured to detect a driving state of the vehicle, an electronic brake electrically operating and configured to generate braking force for at least one driving wheel, and an auxiliary braking force adjusting device configured to control the hydraulic brake and the electronic brake when a failure occurs in the main braking force adjusting device, wherein the auxiliary braking force adjusting device is configured to adjust the braking force of the electronic brake provided on at least one wheel on left and right sides of the vehicle based on a detected value of the sensor unit.

Abstract: A braking system includes a hydraulic brake including a first hydraulic brake provided on one of a front wheel and a rear wheel of a vehicle and a second hydraulic brake provided on the other of the front wheel and the rear wheel of the vehicle, a main braking force adjusting device configured to control braking hydraulic pressure supplied to the first hydraulic brake and the second hydraulic brake, and an auxiliary braking force adjusting device configured to directly control braking hydraulic pressure of the first hydraulic brake when a failure occurs in the main braking force adjusting device, wherein the first hydraulic brake is connected to the main braking force adjusting device via the auxiliary braking force adjusting device.

Abstract: A system for controlling a failure of an environment-friendly vehicle is provided to which a highway driving pilot (HDP) system is applied. The system includes a vehicle control unit (VCU) controller that operates a driving motor, an integrated electric booster (IEB) controller that operates IEB for controlling a brake of the environment-friendly vehicle and generate a request to the VCU controller for regenerative braking, and an HDP controller that calculates a required deceleration of the environment-friendly vehicle based on the situation around the environment-friendly vehicle, determined through cognitive control sensors applied to the environment-friendly vehicle. The HDP controller transmits the required deceleration to the IEB controller. At least one of regenerative braking of the driving motor or braking through the brake is performed based on a type of a fault message output by the IEB controller or a failure in communication between the HDP controller and the IEB controller.

Abstract: A method of operating a brake redundancy device including a main braking controller and a backup braking controller, includes: confirming whether or not a command signal for deceleration of the vehicle has been received, by the backup braking controller; executing a front-wheel braking mode by the backup braking controller when the command signal has been received; determining whether or not an allowable condition for providing the hydraulic pressure to wheel cylinders of rear wheels has been satisfied; and executing a rear-wheel braking mode through a cooperative control of the main braking controller and the backup braking controller when the allowable condition has been satisfied, wherein in the executing of the rear-wheel braking mode, the hydraulic pressure is provided from the backup braking controller to a portion of the main braking controller.

Abstract: A system for controlling a failure of an environment-friendly vehicle is provided to which a highway driving pilot (HDP) system is applied. The system includes a vehicle control unit (VCU) controller that operates a driving motor, an integrated electric booster (IEB) controller that operates IEB for controlling a brake of the environment-friendly vehicle and generate a request to the VCU controller for regenerative braking, and an HDP controller that calculates a required deceleration of the environment-friendly vehicle based on the situation around the environment-friendly vehicle, determined through cognitive control sensors applied to the environment-friendly vehicle. The HDP controller transmits the required deceleration to the IEB controller. At least one of regenerative braking of the driving motor or braking through the brake is performed based on a type of a fault message output by the IEB controller or a failure in communication between the HDP controller and the IEB controller.

Abstract: The present disclosure provides a system and a method for controlling kick-back in an electric booster type brake system capable of reducing a kick-back phenomenon in which a hitting force is transmitted to a brake pedal due to a difference between a high braking hydraulic pressure already generated in a power piston of a second master cylinder by driving a motor and a low braking hydraulic pressure generated in a first master cylinder when a driver steps on a brake pedal, in a fall back situation in which electric power is not smoothly supplied to the motor due to a low voltage of a battery.

Abstract: The present disclosure provides a system and a method for controlling kick-back in an electric booster type brake system capable of reducing a kick-back phenomenon in which a hitting force is transmitted to a brake pedal due to a difference between a high braking hydraulic pressure already generated in a power piston of a second master cylinder by driving a motor and a low braking hydraulic pressure generated in a first master cylinder when a driver steps on a brake pedal, in a fall back situation in which electric power is not smoothly supplied to the motor due to a low voltage of a battery.

Abstract: Disclosed is a brake disc for vehicles including a ring-shaped disc part provided with an insertion space formed at the central region thereof, a hub part disposed within the insertion space and provided with recesses formed on the external circumferential surface thereof, and connection parts configured to connect the disc part and the hub part, wherein each of the connection parts is divided into a curved section extending from the internal circumferential surface of the disc part and having both curved side surfaces and a rectilinear section extending from the curved section, having both flat side surfaces and inserted into each of the recess, and widths of the curved section and the rectilinear section are decreased in a direction toward the hub part.

Abstract: Disclosed is a brake disc for vehicles including a ring-shaped disc part provided with an insertion space formed at the central region thereof, a hub part disposed within the insertion space and provided with recesses formed on the external circumferential surface thereof, and connection parts configured to connect the disc part and the hub part, wherein each of the connection parts is divided into a curved section extending from the internal circumferential surface of the disc part and having both curved side surfaces and a rectilinear section extending from the curved section, having both flat side surfaces and inserted into each of the recess, and widths of the curved section and the rectilinear section are decreased in a direction toward the hub part.