Abstract: The present invention relates to a composition for preventing or treating transplantation rejection or a transplantation rejection disease, comprising a novel compound and a calcineurin inhibitor. A co-administration of the present invention 1) reduces the activity of pathogenic Th1 cells or Th17 cells, 2) increases the activity of Treg cells, 3) has an inhibitory effect against side effects, such as tissue damage, occurring in the sole administration thereof, 4) inhibits various pathogenic pathways, 5) inhibits the cell death of inflammatory cells, and 6) increases the activity of mitochondria, in an in vivo or in vitro allogenic model, a transplantation rejection disease model, a skin transplantation model, and a liver-transplanted patient, and thus inhibits transplantation rejection along with mitigating side effects possibly occurring in the administration of a conventional immunosuppressant alone.

Abstract: A surface-treated copper foil according to exemplary embodiments includes a copper foil layer and a protrusion layer formed on one surface of the copper foil layer. Pores are formed inside the protrusion layer or around a boundary between the copper foil layer and the protrusion layer. Abnormal growth of the protrusions may be prevented through the pores and thus a bonding force with the insulation layer may be improved.

Abstract: Proposed is a spacer grid of a nuclear fuel assembly that may be manufactured using 3D printing with a high degree of design freedom, excluding sheet metal processing and welding processing. The spacer grid of the nuclear fuel assembly has hollow grid cells (110) having inner walls (111) arranged in a square lattice structure and connected to each other by being circumscribed, each of the grid cells including: a plurality of elastic support portions (112) protrudingly provided by being curved inwardly from the inner walls (111) and elastically supporting a fuel rod (10) in a state in which at least three elastic support portions are disposed at equal angles; and a plurality of inner mixing vanes (113) protrudingly provided while each upper tip portion thereof spirally turns along an associated one of the inner walls above the elastic support portions (112).

Abstract: The present invention relates to a top nozzle and a nuclear reactor in which an in-core instrument, which is supposed to be inserted through a top head of a nuclear reactor, is inserted through a guide pin for an upper core plate. In a nuclear reactor including guide pins for aligning a top nozzle for a nuclear fuel assembly with an upper core plate of a nuclear reactor, a guide hole (210) is axially formed through the guide pins (200) and in-core instruments (10) are inserted through the guide holes (210).

Abstract: The present invention relates to a top nozzle and a nuclear reactor in which an in-core instrument, which is supposed to be inserted through a top head of a nuclear reactor, is inserted through a guide pin for an upper core plate. In a nuclear reactor including guide pins for aligning a top nozzle for a nuclear fuel assembly with an upper core plate of a nuclear reactor, a guide hole (210) is axially formed through the guide pins (200) and in-core instruments (10) are inserted through the guide holes (210).

Abstract: The present invention relates to a lower end fitting for reducing flow resistance due to an in-core instrument in a nuclear fuel assembly, that is, a lower end fitting (100) having a plurality of flow holes for a nuclear fuel assembly, in which the flow holes (121) are formed under an assembly groove in which an instrumentation tube (131) for a nuclear fuel assembly is inserted, and at least two or more flow holes (121) are formed at a predetermined distance from the central axis (C) of the instrumentation tube (131).

Abstract: The present invention relates to a lower end fitting for reducing flow resistance due to an in-core instrument in a nuclear fuel assembly, that is, a lower end fitting (100) having a plurality of flow holes for a nuclear fuel assembly, in which the flow holes (121) are formed under an assembly groove in which an instrumentation tube (131) for a nuclear fuel assembly is inserted, and at least two or more flow holes (121) are formed at a predetermined distance from the central axis (C) of the instrumentation tube (131).

Abstract: The present invention relates to a top nozzle and a nuclear reactor in which an in-core instrument, which is supposed to be inserted through a top head of a nuclear reactor, is inserted through a guide pin for an upper core plate. In a nuclear reactor including guide pins for aligning a top nozzle for a nuclear fuel assembly with an upper core plate of a nuclear reactor, a guide hole (210) is axially formed through the guide pins (200) and in-core instruments (10) are inserted through the guide holes (210).

Abstract: Disclosed herein is a spacer grid for a nuclear fuel assembly which is formed from grid strips of an improved structure, thus reducing flow-induced high-frequency vibration. The spacer grid has dimples or grid springs for supporting fuel rods and is formed from a plurality of grid strips assembled in a lattice shape to form lattice cells. Each of the grid strips has at least one slot formed in a planar portion of the grid strip separately from the dimple or grid spring. Therefore, characteristics of the vibration of the spacer grid can be set in a variety of different manners so that flow-induced high-frequency vibration can be reduced.

Abstract: Disclosed herein is a spacer grid for a nuclear fuel assembly. The spacer grid has dimples for supporting fuel rods and is formed from grid strips which are assembled in a lattice shape to form lattice cells. Each grid strip has at least one hole which is formed separately from the dimples. Therefore, when coolant is drawn into the fuel assembly, a pressure difference between opposite sides of the holes is reduced, and friction generated between cut edges of the holes and the coolant reduces the magnitude of the vibration and causes a damping effect, thus reducing flow-induced vibration. The hole formed in the grid strip function to widen the range of the frequency of the flow-induced vibration caused by vortex sheddings formed around the edges of the grid strip, thus reducing the possibility of the generation of resonance with the natural frequency of the spacer grid.

Abstract: Disclosed herein is a spacer grid for a nuclear fuel assembly. The spacer grid has dimples for supporting fuel rods and is formed from grid strips which are assembled in a lattice shape to form lattice cells. Each grid strip has at least one hole which is formed separately from the dimples. Therefore, when coolant is drawn into the fuel assembly, a pressure difference between opposite sides of the holes is reduced, and friction generated between cut edges of the holes and the coolant reduces the magnitude of the vibration and causes a damping effect, thus reducing flow-induced vibration. The hole formed in the grid strip function to widen the range of the frequency of the flow-induced vibration caused by vortex sheddings formed around the edges of the grid strip, thus reducing the possibility of the generation of resonance with the natural frequency of the spacer grid.

Abstract: Disclosed herein is a spacer grid for a nuclear fuel assembly which is formed from grid strips of an improved structure, thus reducing flow-induced high-frequency vibration. The spacer grid has dimples or grid springs for supporting fuel rods and is formed from a plurality of grid strips assembled in a lattice shape to form lattice cells. Each of the grid strips has at least one slot formed in a planar portion of the grid strip separately from the dimple or grid spring. Therefore, characteristics of the vibration of the spacer grid can be set in a variety of different manners so that flow-induced high-frequency vibration can be reduced.