Patents by Inventor Joo-Eun Lee
Joo-Eun Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240172368Abstract: A printed circuit board includes: a first board unit including a plurality of first insulating layers and a plurality of first wiring layers respectively disposed on or in the plurality of first insulating layers; a second board unit including one or more second insulating layers and one or more second wiring layers respectively disposed on or in the one or more second insulating layers; and a first passive device embedded in at least one of the first and second board units. The second board unit is disposed on the first board unit, and the first board unit has a second cavity passing through at least a portion of the plurality of first insulating layers on the first passive device based on a stacking direction of the plurality of first wiring layers.Type: ApplicationFiled: May 26, 2023Publication date: May 23, 2024Applicant: SAMSUNG ELECTRO-MECHANICS CO., LTD.Inventors: Yun Je JI, Yong Hoon KIM, Seung Eun LEE, Joo Hwan JUNG
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Publication number: 20230303978Abstract: Provided are methods of isolating and culturing various cells in a living state including peripheral blood mononuclear cells (PBMCs) isolated from peripheral blood, which use a cell membrane permeabilization method. The methods use a streptococcal hemolytic exotoxin, which binds to cholesterol present in a cell membrane so as to make a pore therein, thereby allowing an exogenous protein to be permeated into the cell, and is a technique of isolating and culturing desired cells in a living state by probing a specific intracellular protein and performing flow cytometry (FACS). According to the methods, various intracellular proteins that could not previously be isolated and cultured from a patient’s blood as well as various tissues may be targeted, and homogeneous cells may be obtained with high purity and high efficiency.Type: ApplicationFiled: April 3, 2023Publication date: September 28, 2023Inventors: Hyo-Soo Kim, Han-Mo Yang, Joo-Eun Lee, Ju-Young Kim
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Patent number: 11236304Abstract: Disclosed are a method for preparing induced pluripotent stem cells from endocardium-derived adult stem cells isolated from peripheral blood and a method for differentiating induced pluripotent stem cells into cardiovascular cells. The endocardium-derived adult stem cells are primary culture cells for preparing induced pluripotent stem cells, can be readily isolated and cultured only with a small amount of peripheral blood, have a high proliferation property so as to be storable without generic variation, and can rapidly ensure a cell number so as to be usable in cell therapy. The endocardium-derived adult stem cells have sternness, thereby having high preparation efficiency, and are derived from the endocardium so as to have the epigenetic memory of cardiovascular cells, thereby having an advantage of being able to be differentiated, after preparing induced pluripotent stem cells, into cardiovascular cells such as endothelial cells, smooth muscle cells and cardiomyocytes with a high efficiency.Type: GrantFiled: November 18, 2015Date of Patent: February 1, 2022Assignee: SEOUL NATIONAL UNIVERSITY HOSPITALInventors: Hyo-Soo Kim, Han-Mo Yang, Ju-Young Kim, Joo-Eun Lee
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Publication number: 20190316092Abstract: Provided are methods of isolating and culturing various cells in a living state including peripheral blood mononuclear cells (PBMCs) isolated from peripheral blood, which use a cell membrane permeabilization method. The methods use a streptococcal hemolytic exotoxin, which binds to cholesterol present in a cell membrane so as to make a pore therein, thereby allowing an exogenous protein to be permeated into the cell, and is a technique of isolating and culturing desired cells in a living state by probing a specific intracellular protein and performing flow cytometry (FACS). According to the methods, various intracellular proteins that could not previously be isolated and cultured from a patient's blood as well as various tissues may be targeted, and homogeneous cells may be obtained with high purity and high efficiency.Type: ApplicationFiled: April 12, 2019Publication date: October 17, 2019Inventors: Hyo-Soo Kim, Han-Mo Yang, Joo-Eun Lee, Ju-Young Kim
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Publication number: 20180362929Abstract: Disclosed are a method for preparing induced pluripotent stem cells from endocardium-derived adult stem cells isolated from peripheral blood and a method for differentiating induced pluripotent stem cells into cardiovascular cells. The endocardium-derived adult stem cells are primary culture cells for preparing induced pluripotent stem cells, can be readily isolated and cultured only with a small amount of peripheral blood, have a high proliferation property so as to be storable without generic variation, and can rapidly ensure a cell number so as to be usable in cell therapy. The endocardium-derived adult stem cells have sternness, thereby having high preparation efficiency, and are derived from the endocardium so as to have the epigenetic memory of cardiovascular cells, thereby having an advantage of being able to be differentiated, after preparing induced pluripotent stem cells, into cardiovascular cells such as endothelial cells, smooth muscle cells and cardiomyocytes with a high efficiency.Type: ApplicationFiled: November 18, 2015Publication date: December 20, 2018Inventors: Hyo-Soo KIM, Han-Mo YANG, Ju-Young KIM, Joo-Eun LEE
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Patent number: 7247595Abstract: A metallocene compound represented by the following Chemical Formula 1: wherein M is a transition metal of Group 4; Cp denotes a cyclopentadienyl ring unsubstituted or substituted by hydrogen, alkyl, cycloalkyl, aryl, alkenyl, alkylaryl, arylalkyl or arylalkenyl radicals; Qs, which are the same or different, are halogen radicals, alkyl, alkenyl, aryl, alkylaryl, or arylakyl radicals having 1 to 20 carbon atoms, or alkylidene radicals having 1 to 20 carbon atoms; A? is methoxymethyl, t-butoxymethyl, tetrahydropyranyl, tetrahydrofuranyl, 1-ethoxyethyl, 1-methyl-1-methoxyethyl, or t-butyl; and a is an integer of 4 to 8. The metallocene compounds in this invention can be strongly supported on the inorganic support, and the supported catalyst of this invention allows for an olefin polymerization process without any fouling in the reactor, and produces a polymer with better morphology and bulk density.Type: GrantFiled: November 30, 2005Date of Patent: July 24, 2007Assignee: LG Chem, Ltd.Inventors: Bun-Yeoul Lee, Jae-Seung Oh, Joo-Eun Lee, Do-Hoon Lee
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Publication number: 20060135351Abstract: The present invention relates to a metallocene compound having a functional group that facilitates the preparation of the supported metallocene catalyst for olefin polymerization and the olefin polymerization process using the same. The metallocene compounds in this invention are strongly supported on the inorganic support due to the strong chemical bond of the ligand of the metallocene compound with the silica surface, which leads to minimize leaching of the catalyst during the activation process. Therefore, the supported catalyst of this invention allows the olefin polymerization process to proceed without any fouling in the reactor with a slurry or a gas phase process, and the morphology and bulk density of the polymer produced are much better defined than those produced by conventional methods.Type: ApplicationFiled: November 30, 2005Publication date: June 22, 2006Inventors: Bun-Yeoul Lee, Jae-Seung Oh, Joo-Eun Lee, Do-Hoon Lee
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Patent number: 7041618Abstract: The present invention relates to a metallocene compound having a functional group that facilitates the preparation of the supported metallocene catalyst for olefin polymerization and the olefin polymerization process using the same. The metallocene compounds in this invention are strongly supported on the inorganic support due to the strong chemical bond of the ligand of the metallocene compound with the silica surface, which leads to minimize leaching of the catalyst during the activation process. Therefore, the supported catalyst of this invention allows the olefin polymerization process to proceed without any fouling in the reactor with a slurry or a gas phase process, and the morphology and bulk density of the polymer produced are much better defined than those produced by conventional methods.Type: GrantFiled: September 18, 2003Date of Patent: May 9, 2006Assignee: LG Chemical Ltd.Inventors: Bun-Yeoul Lee, Jae-Seung Oh, Joo-Eun Lee, Do-Hoon Lee
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Publication number: 20040058804Abstract: The present invention relates to a metallocene compound having a functional group that facilitates the preparation of the supported metallocene catalyst for olefin polymerization and the olefin polymerization process using the same. The metallocene compounds in this invention are strongly supported on the inorganic support due to the strong chemical bond of the ligand of the metallocene compound with the silica surface, which leads to minimize leaching of the catalyst during the activation process. Therefore, the supported catalyst of this invention allows the olefin polymerization process to proceed without any fouling in the reactor with a slurry or a gas phase process, and the morphology and bulk density of the polymer produced are much better defined than those produced by conventional methods.Type: ApplicationFiled: September 18, 2003Publication date: March 25, 2004Applicant: LG Chemical Ltd.Inventors: Bun-Yeoul Lee, Jae-Seung Oh, Joo-Eun Lee, Do-Hoon Lee
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Patent number: 6506919Abstract: The present invention relates to a metallocene compound and the olefin polymerization using the same, particularly to a metallocene compound and the olefin polymerization using this compound on which supported catalysts are easily prepared by the reaction of the ligand containing —(CR12)a—O—SiRbYc ligand (wherein each Y, which can be the same as or different from other Y, is a hydrogen, halogen, alkoxy, aryloxy, amide, or silyloxy radical, each R1, which can be the same as or different from other R1, is a hydrogen radical, or an alkyl, cycloalkyl, aryl, alkenyl, alkylaryl, arylalkyl, or arylalkenyl radical having from 1 to 40 carbon atoms, each R, which can be the same as or different from other R, is an alkyl, cycloalkyl, aryl, alkenyl, alkylaryl, arylalkyl, or arylalkenyl radical having from 1 to 40 carbon atoms, a is an integral number from 1 to 40, c is 1, 2, or 3, and the sum of b and c is 3) with a support.Type: GrantFiled: August 31, 2001Date of Patent: January 14, 2003Assignee: LG Chemical Co., Ltd.Inventors: Jae-Seung Oh, Bun-Yeoul Lee, Joo-Eun Lee, Do-Hoon Lee
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Patent number: D747681Type: GrantFiled: September 24, 2014Date of Patent: January 19, 2016Assignee: IOTTIE, INC.Inventors: Kyu Seop Lee, Joo Eun Lee, Phisitsuk Paul Sukphisit
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Patent number: D748615Type: GrantFiled: October 16, 2014Date of Patent: February 2, 2016Assignee: IOTTIE, INC.Inventors: Kyu Seop Lee, Phisitsuk Paul Sukphisit, Joo Eun Lee