Abstract: A multiple chamber container forming and filling method includes (i) forming at least one strong seal around a periphery of first and second sheets so as to leave an opening between the first and second sheets; (ii) forming a temporary peel seal across the opening; (iii) forming a mixing peel seal between the first and second sheets so as to separate a diluent chamber from a powdered drug chamber; (iv) adding diluent to the diluent chamber; (v) sterilizing the multiple chamber container including the diluent; (vi) opening the temporary peel seal in an aseptic environment; (vii) adding powdered drug to the powdered drug chamber through the opening; and (viii) strong sealing the opening so as to be closed.

Abstract: A multiple chamber container forming and filling method includes (i) forming at least one strong seal around a periphery of first and second sheets so as to leave an opening between the first and second sheets; (ii) forming a temporary peel seal across the opening; (iii) forming a mixing peel seal between the first and second sheets so as to separate a diluent chamber from a powdered drug chamber; (iv) adding diluent to the diluent chamber; (v) sterilizing the multiple chamber container including the diluent; (vi) opening the temporary peel seal in an aseptic environment; (vii) adding powdered drug to the powdered drug chamber through the opening; and (viii) strong sealing the opening so as to be closed.

Abstract: A multiple chamber container includes a first sheet; a second sheet; a first peel seal between the first and second sheets, the first peel seal extending across the first and second sheets; wherein at a first time at least one strong seal is provided around a periphery of the first and second sheets so as to leave an opening between the first and second sheets, and wherein a second peel seal is provided between the first and second sheets, the second peel seal extending across the opening between the first and second sheets; and wherein at a second time the second peel seal is removed and the at least one strong seal is extended to seal the opening between the first and second sheets.

Abstract: A needleless access port is assembled from parts sealed to a flexible container, such as a container for intravenous infusion, parenteral nutrition or transfusion. The port includes a lower housing for sealing to the container, the lower housing having an upright tower for mounting an upper housing. The upper housing has at least one connector or valve and a sleeve for mounting to the tower. The sleeve includes connectors so the upper housing can be mounted in a first, upper resting position, and a second lower, active position, for adding liquid to the container or for removing liquid from the container. Even after assembly to a container, the upper housing may be removed and the lower housing may be used instead with a standard IV spike set.

Abstract: A medicant reconstitution system is provided which has a generally flexible fluid bag with associated administration and reconstitution ports. The reconstitution port is adapted for receiving a medicant container and the administration port is for administering a medical fluid to a patient. According to one aspect of the present invention, the administration and reconstitution ports are integrated in a relatively rigid port structure. According to another aspect of the present invention, the reconstitution port receives a piercing member which is rotatable to a selected position to establish fluid flow. According to yet another aspect of the present invention, one of the reconstitution port and the piercing member includes a cutting edge, while the other includes a frangible member. Contact between the cutting edge and the frangible member opens the frangible member to establish fluid flow.

Abstract: A medicant reconstitution system is provided which has a generally flexible fluid bag with associated administration and reconstitution ports. The reconstitution port is adapted for receiving a medicant container and the administration port is for administering a medical fluid to a patient. According to one aspect of the present invention, the administration and reconstitution ports are integrated in a relatively rigid port structure. According to another aspect of the present invention, the reconstitution port receives a piercing member which is rotatable to a selected position to establish fluid flow. According to yet another aspect of the present invention, one of the reconstitution port and the piercing member includes a cutting edge, while the other includes a frangible member. Contact between the cutting edge and the frangible member opens the frangible member to establish fluid flow.

Abstract: A medicant reconstitution system is provided which has a generally flexible fluid bag with associated administration and reconstitution ports. The reconstitution port is adapted for receiving a medicant container and the administration port is for administering a medical fluid to a patient. According to one aspect of the present invention, the administration and reconstitution ports are integrated in a relatively rigid port structure. According to another aspect of the present invention, the reconstitution port receives a piercing member which is rotatable to a selected position to establish fluid flow. According to yet another aspect of the present invention, one of the reconstitution port and the piercing member includes a cutting edge, while the other includes a frangible member. Contact between the cutting edge and the frangible member opens the frangible member to establish fluid flow.

Abstract: A method and device for facilitating fluid communication between a sealed container having an access port and at least one fluid passageway. The device includes a connector provided with a body that defines a fluid passageway between first and second ends of the body. The first end of the body is configured for receiving the fluid source, and the second end is configured for receiving an access port of the container. A locking member is associated with the body and prevents movement of the body relative to the access port when the locking member is in a locked position. The device can be used for the transfer of cytotoxic or other drugs (i.e., fluids) to the container and may remain attached to the access port and used to administer a drug from the container to a patient by means of an administration set with a male luer connector.

Abstract: A method and device for facilitating fluid communication between a sealed container having an access port and at least one fluid passageway. The device includes a connector provided with a body that defines a fluid passageway between first and second ends of the body. The first end of the body is configured for receiving the fluid source, and the second end is configured for receiving an access port of the container. A locking member is associated with the body and prevents movement of the body relative to the access port when the locking member is in a locked position. The device can be used for the transfer of cytotoxic or other drugs (i.e., fluids) to the container and may remain attached to the access port and used to administer a drug from the container to a patient by means of an administration set with a male luer connector.