Abstract: A printing apparatus is disclosed. The printing apparatus comprises a rotating housing comprising a wall with an inner side defining a chamber and an outer side. The wall has a bore communicating the inner side and the outer side, and the chamber is to receive a fluid container. The printing apparatus also comprises a fix frame holding the rotating housing. The printing apparatus further comprises an optical sensor comprising an emitter to issue a detecting optical signal through the bore and a receiver to receive a detected optical signal associated to the detecting optical signal. The detected signal is sent to a controller to determine whether the fluid container is present in the rotating housing.

Abstract: Disclosed herein are novel compounds comprising antisense oligonucleotides that regulate the splicing of NUMB. In particular, an antisense oligonucleotide for reducing inclusion of NUMB exon 9 in a population of mature NUMB transcripts is provided. The antisense oligonucleotide comprises a sequence of at least 7 nucleotides that is complementary to a target region within exon 9 of a NUMB transcript. Pharmaceutical compositions comprising the antisense oligonucleotide and methods of treating a proliferative disease using the compounds or compositions of the invention are also described.

Abstract: The present invention relates to compound 1 or 2 or the composition comprising it. The present invention also relates to a process for obtaining compound 1 or 2, as well as to the use thereof for detecting GHB in beverages. An equipment or kit for use in detecting GHB in beverages is also included.

Abstract: The present invention relates to compound 1 or 2 or the composition comprising it. The present invention also relates to a process for obtaining compound 1 or 2, as well as to the use thereof for detecting GHB in beverages and urine. An equipment or kit for use in detecting GHB in beverages and urine is also included.

Abstract: Disclosed herein are novel compounds comprising antisense oligonucleotides that regulate the splicing of NUMB. In particular, an antisense oligonucleotide for reducing inclusion of NUMB exon 9 in a population of mature NUMB transcripts is provided. The antisense oligonucleotide comprises a sequence of at least 7 nucleotides that is complementary to a target region within exon 9 of a NUMB transcript. Pharmaceutical compositions comprising the antisense oligonucleotide and methods of treating a proliferative disease using the compounds or compositions of the invention are also described.

Abstract: There is disclosed a method of supplying an n-channel transistor, operating as a voltage regulator, with a supply voltage and providing a control voltage to the n-channel transistor. The n-channel transistor is controlled by the control voltage to output an operating voltage of a printhead at a predetermined voltage.

Abstract: A system comprises a printhead including a nozzle, a temperature sensor and a processor. The temperature sensor detects the temperature of a location of a print surface upon firing the nozzle to eject a drop of printing fluid to the location of the print surface. The processor determines whether the nozzle ejected the drop properly using the detected temperature.

Abstract: There is provided a print apparatus and a media roll for the print apparatus, comprising a media identifier located on an end of a core section of the media roll. A type of media loaded into the print apparatus is determined by sensing the media identifier on the media roll using a non-contact sensor to scan the end of the core section.

Abstract: Disclosed herein are novel compounds comprising antisense oligonucleotides that regulate the splicing of NUMB. In particular, an antisense oligonucleotide for reducing inclusion of NUMB exon 9 in a population of mature NUMB transcripts is provided. The antisense oligonucleotide comprises a sequence of at least 7 nucleotides that is complementary to a target region within exon 9 of a NUMB transcript. Pharmaceutical compositions comprising the antisense oligonucleotide and methods of treating a proliferative disease using the compounds or compositions of the invention are also described.

Abstract: A printing apparatus is disclosed. The printing apparatus comprises a rotating housing comprising a wall with an inner side defining a chamber and an outer side. The wall has a bore communicating the inner side and the outer side, and the chamber is to receive a fluid container. The printing apparatus also comprises a fix frame holding the rotating housing. The printing apparatus further comprises an optical sensor comprising an emitter to issue a detecting optical signal through the bore and a receiver to receive a detected optical signal associated to the detecting optical signal. The detected signal is sent to a controller to determine whether the fluid container is present in the rotating housing.

Abstract: Disclosed herein is an electric motor control circuit, a printing device, and a method of overvoltage protection for an electric motor. The electric motor control circuit comprises a controller, a voltage converter to generate a supply voltage of the controller from a voltage at terminals of the electric motor and a switchable braking circuit connected to the motor terminals. The controller is to activate the braking circuit if the voltage at the motor terminals exceeds a threshold voltage while the controller is in an off-state.

Abstract: There is disclosed a method of supplying an n-channel transistor, operating as a voltage regulator, with a supply voltage and providing a control voltage to the n-channel transistor. The n-channel transistor is controlled by the control voltage to output an operating voltage of a printhead at a predetermined voltage.

Abstract: A system comprises a printhead including a nozzle, a temperature sensor and a processor. The temperature sensor detects the temperature of a location of a print surface upon firing the nozzle to eject a drop of printing fluid to the location of the print surface. The processor determines whether the nozzle ejected the drop properly using the detected temperature.

Abstract: A die controller to control a fluidic die having a plurality of primitives each including a plurality of nozzles addressed by a same set of addresses. The die controller provides operational data including a series of actuation data groups to the fluidic die to actuate the nozzles to eject fluid to form an article, each actuation data group including a series of fire pulse groups, with each fire pulse group corresponding to a different address of the set of addresses and including a set of actuation data for each primitive and a set of start bits to initiate actuation of the nozzles based on the actuation data of the immediately preceding fire pulse group. The die controller to provide a blank fire pulse group immediately following a last fire pulse group of the series of fire pulse groups of each actuation data group when operating in an edge sharpness mode.

Abstract: It is disclosed a motor identification method for determine possible incorrect connections in a system comprising a plurality of motors corresponding to a plurality of sub-systems, the method comprising: applying an input to at least one of the motors causing its movement; and determining a detection signal corresponding to a position, speed or acceleration of the motor during a detection period; wherein the system comprises a memory storing a set of characteristic signals corresponding to at least some of the sub-systems and wherein the method comprises comparing, by a controller, the detection signal with the set of characteristic signals and correlating the at least one of the motors to a determined sub-system.

Abstract: Example systems to determine print fluid ejection nozzle health for a printer device are disclosed along with corresponding methods. In an example, the system includes an image recording device to record an image of print fluid ejected from a print fluid ejection nozzle and disposed on a printable surface. In addition, the system includes an image processor to analyse the image to provide a result based on a characteristic of the image that are representative of the print fluid disposed on the printable surface. Further, the system includes a controller to receive the result and assign a nozzle health category to the print fluid ejection nozzle in dependence on the result.

Abstract: Devices and methods for calibrating communication lines are disclosed. A clock sets a frequency of transmission through a communication line. A delay compensator, comprising multi-tap delay lines introduces delays in a transmitted message to compensate for skew in the communication line. An error comparator, coupled to the delay compensator, identifies errors in the messages transmitted through the multi-tap delay lines above an error margin. A delay selector, coupled to the error comparator and to the delay compensator, selects taps of the multi-tap delay lines of the delay compensator. Taps of the multi-tap delay lines where no errors are identified for the selected clock frequency are stored in a memory.

Abstract: A die controller to control a fluidic die having a plurality of primitives each including a plurality of nozzles addressed by a same set of addresses. The die controller provides operational data including a series of actuation data groups to the fluidic die to actuate the nozzles to eject fluid to form an article, each actuation data group including a series of fire pulse groups, with each fire pulse group corresponding to a different address of the set of addresses and including a set of actuation data for each primitive and a set of start bits to initiate actuation of the nozzles based on the actuation data of the immediately preceding fire pulse group. The die controller to provide a blank fire pulse group immediately following a last fire pulse group of the series of fire pulse groups of each actuation data group when operating in an edge sharpness mode.

Abstract: Devices and methods for calibrating communication lines are disclosed. A clock sets a frequency of transmission through a communication line. A delay compensator, comprising multi-tap delay lines introduces delays in a transmitted message to compensate for skew in the communication line. An error comparator, coupled to the delay compensator, identifies errors in the messages transmitted through the multi-tap delay lines above an error margin. A delay selector, coupled to the error comparator and to the delay compensator, selects taps of the multi-tap delay lines of the delay compensator. Taps of the multi-tap delay lines where no errors are identified for the selected clock frequency are stored in a memory.

Abstract: The invention discloses an effervescent candy material characterized by specific particle size of the alkali metal bicarbonate compound, by food acid partially in particulate form and by selected moisture content. The invention also discloses candies or lollipops entirely or partially made of the effervescent material as well as processes for the preparation of said material.