Patents by Inventor José Luis Adrio Fondevila

José Luis Adrio Fondevila has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9453004
    Abstract: Formylated xanthocillin analogs can be used in the treatment of neurodegenerative diseases. The analogs can be prepared synthetically, and at least some of the analogs can be obtained from a microorganism strain of the Penicillium chrysogenum species.
    Type: Grant
    Filed: February 6, 2013
    Date of Patent: September 27, 2016
    Assignee: NEURON BIOPHARMA, S.A.
    Inventors: Maria del Carmen Ramos Martin, Sonia Campoy Garcia, Javier Santos Burgos Muñoz, José Luis Adrio Fondevila, Javier Velasco Alvarez
  • Publication number: 20160145660
    Abstract: The present invention relates to the Rhodosporidium toruloides CECT 13085 strain, as well as to uses thereof for obtaining microbial biomass rich in triglycerides and for producing oils of a microbial origin in the presence of lignocellulosic biomass hydrolysates.
    Type: Application
    Filed: June 9, 2014
    Publication date: May 26, 2016
    Inventors: Sonia CAMPOY GARCÍA, Jordi GIBERT AMAT, Armando LARA CAMBIL, Beatriz SUÁREZ GONZÁLEZ, Javier VELASCO ALVAREZ, José Luis ADRIO FONDEVILA
  • Publication number: 20150011621
    Abstract: Formylated xanthocillin analogs can be used in the treatment of neurodegenerative diseases. The analogs can be prepared synthetically, and at least some of the analogs can be obtained from a microorganism strain of the Penicillium chrysogenum species.
    Type: Application
    Filed: February 2, 2013
    Publication date: January 8, 2015
    Inventors: Maria del Carmen Ramos Martin, Sonia Campoy García, Javier Santos Burgos Muñoz, José Luis Adrio Fondevila, Javier Velasco Alvarez
  • Publication number: 20140309295
    Abstract: The present invention describes a compound of formula (I) its hydroxy acid form, the pharmaceutically acceptable salts of said hydroxy acid and pharmaceutically acceptable prodrugs and solvates of the compound and of its hydroxy acid form and, in particular, said compound, its hydroxy acid form, salts, etc. for its use in the prevention of: neurodegenerative diseases, cognitive deterioration, diseases associated with undesired oxidation, age-associated pathological processes and progeria, epilepsy, epileptic seizures and convulsions, cardiovascular diseases such as atherosclerosis, atrial fibrillation, dyslipemia, hypercholesterolemia, hyperlipidemia, and hypertriglyceridemia, or fungal or viral infections.
    Type: Application
    Filed: June 25, 2014
    Publication date: October 16, 2014
    Inventors: Javier Santos BURGOS MUÑOZ, José Luis ADRIO FONDEVILA, Maria del Carmen RAMOS MARTÍN, Saleta SIERRA ÁVILA, Juan Maria ALFARO SÁNCHEZ, Carlos RAMÍREZ MORENO, Sonia CAMPOY GARCIA, Javier VELASCO ALVAREZ, Ángel RUMBERO SÁNCHEZ
  • Patent number: 8647849
    Abstract: The present invention relates to a process for obtaining a mixture of fatty acid esters, suitable as a combustible or fuel in diesel cycle engines, comprising: a) the obtaining of a microbial biomass with a triglyceride content equal to or greater than 20% by dry weight, by means of the use of an oleaginous microorganism using glycerin as a carbon source; and b) the conversion of the triglycerides contained in the biomass obtained in step a) into a mixture of fatty acid esters. The invention likewise relates to said oleaginous microorganism, to a process for its selection and to polynucleotides obtained therefrom.
    Type: Grant
    Filed: March 25, 2009
    Date of Patent: February 11, 2014
    Assignee: Neol Biosolutions, S.A.
    Inventors: Javier Velasco Alvarez, José Luis Adrio Fondevila, M'del Carmen Ronchel Barreno, Alberto Zafra Gómez, Magdalena Valdivieso Ugarte
  • Publication number: 20130197073
    Abstract: The present invention describes a compound of formula (I) its hydroxy acid form, the pharmaceutically acceptable salts of said hydroxy acid and pharmaceutically acceptable prodrugs and solvates of the compound and of its hydroxy acid form and, in particular, said compound, its hydroxy acid form, salts, etc. for use in the prevention of: neurodegenerative diseases, cognitive impairment, diseases associated with undesired oxidation, age-associated pathological processes and progeria, cardiovascular diseases such as atherosclerosis, atrial fibrillation, dyslipidemia, hypercholesterolemia, hyperlipidemia, and hypertriglyceridemia, inflammation or inflammatory processes, or epilepsy, epileptic seizures and convulsions.
    Type: Application
    Filed: October 11, 2011
    Publication date: August 1, 2013
    Applicant: NEURON BIOPHARMA, S.A.
    Inventors: Javier Santos Burgos Muñoz, Carlos Ramírez Moreno, Saleta Sierra Ávila, Maria del Carmen Ramos Martín, Juan María Alfaro Sánchez, José Luis Adrio Fondevila, Javier Velasco Alvarez
  • Publication number: 20120095091
    Abstract: The present invention describes a compound of formula (I) its hydroxy acid form, the pharmaceutically acceptable salts of said hydroxy acid and pharmaceutically acceptable prodrugs and solvates of the compound and of its hydroxy acid form and, in particular, said compound, its hydroxy acid form, salts, etc. for its use in the prevention of: neurodegenerative diseases, cognitive deterioration, diseases associated with undesired oxidation, age-associated pathological processes and progeria, epilepsy, epileptic seizures and convulsions, cardiovascular diseases such as atherosclerosis, atrial fibrillation, dyslipemia, hypercholesterolemia, hyperlipidemia, and hypertriglyceridemia, or fungal or viral infections.
    Type: Application
    Filed: April 16, 2010
    Publication date: April 19, 2012
    Applicant: Neuron Biopharma S.A
    Inventors: Javier Santos Burgos Muñoz, José Luis Adrio Fondevila, Maria del Carmen Ramos Martín, Saleta Sierra Ávila, Juan María Alfaro Sánchez, Carlos Ramírez Moreno, Sonia Campoy García, Javier Velasco Alvarez, Ángel Rumbero Sánchez
  • Publication number: 20110189726
    Abstract: The invention relates to a process for obtaining monacolin J derivatives (I), wherein R1 is COR2, wherein R2 is selected from C1-C15 alkyl, C3-C15 cycloalkyl, C2-C15 alkenyl, C2-C15 alkynyl, aryl and heterocyclyl; which comprises producing monacolin J by fermentation from a monacolin J-producing microorganism; and acylating the hydroxyl group present in the C8 position of the monacolin J previously obtained by means of adding a suitable acylating agent to the fermentation medium to obtain the desired monacolin J derivative (I).
    Type: Application
    Filed: October 14, 2009
    Publication date: August 4, 2011
    Applicant: NEURON BIOPHARMA, S.A.
    Inventors: Sonia Campoy Garcia, Alberto Zafea Gómez, José Luis Adrio Fondevila, Javier Velasco Alvarez
  • Publication number: 20110088312
    Abstract: The present invention relates to a process for obtaining a mixture of fatty acid esters, suitable as a combustible or fuel in diesel cycle engines, comprising: a) the obtaining of a microbial biomass with a triglyceride content equal to or greater than 20% by dry weight, by means of the use of an oleaginous microorganism using glycerin as a carbon source; and b) the conversion of the triglycerides contained in the biomass obtained in step a) into a mixture of fatty acid esters. The invention likewise relates to said oleaginous microorganism, to a process for its selection and to polynucleotides obtained therefrom.
    Type: Application
    Filed: March 25, 2009
    Publication date: April 21, 2011
    Applicant: NEURON BIOPHARMA, S.A.
    Inventors: Javier Velasco Alvarez, José Luis Adrio Fondevila, M' del Carmen Ronchel Barreno, Alberto Zafra Gómez, Magdalena Valdivieso Ugarte