Patents by Inventor Jose Agustin Quincoces Suarez

Jose Agustin Quincoces Suarez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR THE PRODUCTION OF ANTITUMOUR PHARMACEUTICAL COMPOSITIONS USING PUSH-PULL BUTADIENES, COMPOUNDS AND USES THEREOF
    Publication number: 20230130823
    Abstract: The present invention reports the obtaining of carbonyl compounds and derivatives, through syntheses with high yield and purity, providing anti-humoral active principles with selective antiproliferative properties and anti-metastatic activity. The present invention refers to the development of new polyfunctional push-pull butadienes and their O and C-prenylated, benzoylated and iodide derivatives, with high electronic conjugation in the lateral chain. These compounds exhibit high anti-tumor selectivity, causing cell death by apoptosis, also show anti-metastatic and non-mutagenic properties in the experimental studies performed.
    Type: Application
    Filed: October 23, 2020
    Publication date: April 27, 2023
    Applicants: ANHANGUERA EDUCACIONAL PARTICIPAÇÕES S/A, FUNDAÇÃO UNIVERSIDADE FEDERAL DO ABC, INSTITUTO BUTANTAN
    Inventors: Anderson ORZARI RIBEIRO, Carolina PASSARELLI GONÇALVES, Durvanei AUGUSTO MARIA, José Agustín QUINCOCES SUÁREZ, Manuel SALUSTIANO ALMEIDA SAAVEDRA
  • Pharmaceutical composition and use of the pharmaceutical composition for the treatment, prophylaxis or prevention of neoplastic diseases in humans and animals
    Patent number: 9381169
    Abstract: The present invention relates to pharmaceutical compositions comprising polyfunctional metal phenolates that have biological applications as an anticancer adjuvant, cytoprotective antimetastatic agents and antimutagenic agents when associated with chemotherapy drugs. The present invention further relates to the use of said polyfunctional metal phenolates in the preparation of drugs for the treatment, prophylaxis or prevention of neoplasic diseases in humans and animals.
    Type: Grant
    Filed: November 11, 2009
    Date of Patent: July 5, 2016
    Assignees: UNIVERSIDADE BANDEIRANTE DE SÃO PAULO—ACADEMIA PAULISTA ANCHIETA S/C LT, FUNDAÇ ÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO—FAPESP
    Inventors: José Agustin Quincoces Suárez, Durvanei Augusto Maria, Paulo Celso Pardi, Fernanda Faião Flores, Reginaldo Pereira Santos, Daniela Gonçales Rando
  • Methods to prepare penta-1,4-dien-3-ones and substituted cyclohexanones and derivatives with antitumoral and antiparasitic properties, the compounds and their uses
    Patent number: 8859625
    Abstract: The present invention refers to new derivatives of the penta-1,4-dien-3-ones, as well as their processes of preparation. These compounds present strong antitumoral activity and promising antiparasitic action, behaving as almost atoxic by laboratory assays and also by hystopathologic studies. The present invention refers also to a pharmaceutical composition including the referred compounds, method of treatment for cancer and parasitic diseases.
    Type: Grant
    Filed: July 6, 2007
    Date of Patent: October 14, 2014
    Assignee: Universidade Bandeirante de Sao Paulo-Academia, Paulista Anchieta S/C Ltda
    Inventors: José Agustin Quincoces Suárez, Durvanei Augusto Maria, Daniela Goncales Rando, Clizete Aparecida Sbravate Martins, Paulo Celso Pardi, Pamela Oliveira De Souza
  • PHARMACEUTICAL COMPOSITION AND USE OF THE PHARMACEUTICAL COMPOSITION FOR THE TREATMENT, PROPHYLAXIS OR PREVENTION OF NEOPLASTIC DISEASES IN HUMANS AND ANIMALS
    Publication number: 20120082703
    Abstract: The present invention relates to pharmaceutical compositions comprising polyfunctional metal phenolates that have biological applications as an anticancer adjuvant, cytoprotective antimetastatic agents and antimutagenic agents when associated with chemotherapy drugs. The present invention further relates to the use of said polyfunctional metal phenolates in the preparation of drugs for the treatment, prophylaxis or prevention of neoplasic diseases in humans and animals.
    Type: Application
    Filed: November 11, 2009
    Publication date: April 5, 2012
    Applicant: UNIVERSIDADE BANDEIRANTE DE SAO PAULO-ACADEMIA PAULISTA ANCHETA S/C LTDA
    Inventors: José Agustín Quincoces Suárez, Durvanei Augusto Maria, Paulo Celso Pardi, Fernanda Faião Flores, Reginaldo Pereira Santos, Daniela Gonçales Rando
  • METHODS TO PREPARE PENTA-1,4-DIEN-3-ONES AND SUBSTITUTED CYCLOHEXANONES AND DERIVATIVES WITH ANTITUMORAL AND ANTIPARASITIC PROPERTIES, THE COMPOUNDS AND THEIR USES
    Publication number: 20100029763
    Abstract: The present invention refers to new derivatives of the penta-1,4-dien-3-ones, as well as their processes of preparation. These compounds present strong antitumoral activity and promising antiparasitic action, behaving as almost atoxic by laboratory assays and also by hystopathologic studies. The present invention refers also to a pharmaceutical composition including the referred compounds, method of treatment for cancer and parasitic diseases.
    Type: Application
    Filed: July 6, 2007
    Publication date: February 4, 2010
    Inventors: Jose Agustin Quincoces Suarez, Durvanei Augusto Maria, Daniela Goncales Rando, Clizete Aparecida Sbravaate Martins, Paulo Celso Pardi, Pamela Oliveira De Souza
  • SUBSTITUTED HYDROXYACETOPHENONE DERIVATIVES
    Publication number: 20090234023
    Abstract: The present invention relates to substituted hydroxyacetophenone derivatives having antiproliferative and antimicrobial properties, to pharmaceutical compositions containing them, as well as to a method of preparing them. Moreover, the hydroxyacetophenone derivatives according to the invention can serve as organic intermediates for the preparation of biologically active compounds.
    Type: Application
    Filed: July 6, 2005
    Publication date: September 17, 2009
    Applicant: Riemser Arzneimittel AG
    Inventors: Jose Agustin Quincoces Suarez, Klaus Peseke, Ernesto Estrada Roger
  • Method for the preparation of 1,5-bis(4-hydroxy-3-metoxy-phenyl)-penta-1,4-dien-3-one and derivatives with antitumoral properties
    Patent number: 7432401
    Abstract: This patent of invention reports the method for the preparation of 1,5-bis(4-hydroxy-3-methoxyphenyl)-penta-1,4-dien-3-one and derivatives with antitumoral properties: the sample denominated 37 compound was obtained with high yield and purity with ultrasonic technique presenting cytostatic activity (growth inhibition) in the concentrations evaluated and cytotoxic activity (cellular death) from the concentration of 0.25 mg/mL against nine different types of human cancer cell lines. This compound has a LD50, equals to 8.54 g/Kg. That means this product can be considered itself as practically nontoxic. Doxorubicin, anticarcinogen medicine used as reference in all these tests, is a product extremely toxic (LD50 of 20 mg/Kg) and it does not inhibit the growth of Mama NCI-ADR cell line (the one that expresses the phenotype of resistance against multiple drugs), therefore, out product presented a strong cytostatic activity.
    Type: Grant
    Filed: November 28, 2003
    Date of Patent: October 7, 2008
    Assignee: Fundação de Amparo a Pesquisa Do Estado de São Paulo
    Inventors: José Agustin Quincoces Suárez, Klaus Peseke, Markus Kordian, João Ernesto Carvalho, Luciana Konecny Kohn, Márcia Aparecida Antônio, Heloiza Brunhari