Abstract: The present invention relates to compounds of formula (I) for use in preventing and/or treating cancer.

Abstract: The invention comprises a method to increase the water absorption of tissue paper towel products by incorporating super-absorbent polymers (SAP) in between the laminated tissue plies. The SAP is dosed in selected places in the tissue towel manufacturing process without the need to substantially change the current converting or manufacturing process, or the major equipment that is used or the properties of the base sheet tissue paper.

Abstract: A cell model is disclosed that has a phenotypic profile, expressing at least one drug biotransformation enzyme. This model includes a cell having cytochrome reductase activity, transformed with at least one expression vector comprising a DNA sequence for a drug biotransformation enzyme. The method is based on the use of expression vectors coding for the sense and anti-sense mRNA of the Phase I and Phase II drug biotransformation enzymes showing a greatest variability in humans for transforming cells expressing cytochrome reductase activity. Such vectors can modulate (increase or decrease) the individualised expression of an enzyme without affecting the other enzymes. This cell model can reproduce in vitro the metabolic idiosyncrasy of humans. It is applicable in the study of development of new drugs, specifically in the study of metabolism, potential idiosyncratic hepatotoxicity, medicament interactions, etc., of new drugs.