Patents by Inventor Jose Lino Vasconcelos Da Costa
Jose Lino Vasconcelos Da Costa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230405885Abstract: Solution casting a nanostructure. Preparing a template by ablating nanoholes in a substrate using single-femtosecond laser machining. Replicating the nanoholes by applying a solution of a polymer and a solvent into the template. After the solvent has substantially dissipated, removing the replica from the substrate.Type: ApplicationFiled: April 25, 2023Publication date: December 21, 2023Inventors: William Hudson Hofmeister, Alexander Yuryevich Terekhov, Jose Lino Vasconcelos da Costa, Kathleen Stacia Lansford, Deepak Rajput, Lloyd M. Davis
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Patent number: 11667062Abstract: Solution casting a nanostructure. Preparing a template by ablating nanoholes in a substrate using single-femtosecond laser machining. Replicating the nanoholes by applying a solution of a polymer and a solvent into the template. After the solvent has substantially dissipated, removing the replica from the substrate.Type: GrantFiled: October 4, 2021Date of Patent: June 6, 2023Assignee: ULTRA SMALL FIBERS, LLCInventors: William Hudson Hofmeister, Alexander Yuryevich Terekhov, Jose Lino Vasconcelos da Costa, Kathleen Stacia Lansford, Deepak Rajput, Lloyd M. Davis
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Publication number: 20220194633Abstract: One or more electrospray emitters form an electrospray thruster, suitable for generating thrust for maneuvering and/or moving a structure to which the thruster is attached in three-dimensional space. The thruster includes a reservoir containing a fluid, preferably an ionic liquid (IL) fluid. Each electrospray emitter includes a dielectric, with channel(s) formed through a thickness thereof, and an extraction electrode, preferably an extraction grid, on an opposite side of the dielectric from the reservoir. Upon application of a sufficient electric potential differential between the extraction electrode and the fluid, the fluid flows through the channels from the reservoir, forms a Taylor cone at an outlet of each channel, and is ejected in the direction of the extraction grid to generate a thrust by the thruster for movement and/or maneuvering of the structure to which the thruster is attached.Type: ApplicationFiled: December 10, 2021Publication date: June 23, 2022Inventors: Jose Lino Vasconcelos da Costa, Trevor Michael Moeller, Justin Michael Jones, Brian Keith Canfield, Alexander Yuryevich Terekhov, Joshua Harrison Howell
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Publication number: 20220024084Abstract: Solution casting a nanostructure. Preparing a template by ablating nanoholes in a substrate using single-femtosecond laser machining. Replicating the nanoholes by applying a solution of a polymer and a solvent into the template. After the solvent has substantially dissipated, removing the replica from the substrate.Type: ApplicationFiled: October 4, 2021Publication date: January 27, 2022Inventors: William Hudson Hofmeister, Alexander Yuryevich Terekhov, Jose Lino Vasconcelos da Costa, Kathleen Stacia Lansford, Deepak Rajput, Lloyd M. Davis
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Patent number: 11155007Abstract: Solution casting a nanostructure. Preparing a template by ablating nanoholes in a substrate using single-femtosecond laser machining. Replicating the nanoholes by applying a solution of a polymer and a solvent into the template. After the solvent has substantially dissipated, removing the replica from the substrate.Type: GrantFiled: December 4, 2014Date of Patent: October 26, 2021Assignee: ULTRA SMALL FIBERS, LLCInventors: William Hudson Hofmeister, Alexander Yuryevich Terekhov, Jose Lino Vasconcelos da Costa, Kathleen Stacia Lansford, Deepak Rajput, Lloyd M. Davis
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Patent number: 10941380Abstract: Embodiments of the presently disclosed subject matter provide biomimetic cell culture substrates comprising highly tunable patterned polymer nanofiber matrices capable of modulating expression of critical self-renewal factors and markers of cell-cell interaction to maintain stemness of human mesenchymal stem cells in vitro. Embodiments of the presently-disclosed subject matter also provide scalable, highly repeatable methods of making biomimetic cell culture substrates by hot pressing thermoplastic polymer films into femtosecond laser-ablated nanopore molds to form patterned polymer nanofiber matrices on flat thermoplastic substrates.Type: GrantFiled: February 3, 2016Date of Patent: March 9, 2021Assignee: Ultra Small Fibers, LLCInventors: William Hudson Hofmeister, Lucas Hofmeister, Alexander Yuryevich Terekhov, Jose Lino Vasconcelos da Costa
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Publication number: 20200360923Abstract: A semipermeable ultrathin polymer membrane comprises a substantially optically transparent polymer film having a surface area to thickness ratio of at least 1,000,000:1, and an array of precisely spatially ordered pores of a user-selected diameter defined therethrough. Such membranes can be fabricated by providing a mold having a patterned array of nanoholes femtosecond laser ablated in a surface thereof; applying a first polymer solution onto the mold surface so that the first polymer solution infiltrates the nanoholes; allowing the first polymer solution to dry and form a replica of the mold having a plurality of freestanding nanoneedles extending from a surface of the replica; removing the replica from the mold; coating the replica surface with a second polymer solution; drying the second polymer solution to form a porous polymer film; and dissolving the replica in a solvent to release the film from the replica as a semipermeable ultrathin polymer membrane.Type: ApplicationFiled: July 30, 2020Publication date: November 19, 2020Inventors: William Hudson Hofmeister, Alexander Yuryevich Terekhov, Jose Lino Vasconcelos da Costa
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Patent number: 10758902Abstract: A semipermeable ultrathin polymer membrane comprises a substantially optically transparent polymer film having a surface area to thickness ratio of at least 1,000,000:1, and an array of precisely spatially ordered pores of a user-selected diameter defined therethrough. Such membranes can be fabricated by providing a mold having a patterned array of nanoholes femtosecond laser ablated in a surface thereof; applying a first polymer solution onto the mold surface so that the first polymer solution infiltrates the nanoholes; allowing the first polymer solution to dry and form a replica of the mold having a plurality of freestanding nanoneedles extending from a surface of the replica; removing the replica from the mold; coating the replica surface with a second polymer solution; drying the second polymer solution to form a porous polymer film; and dissolving the replica in a solvent to release the film from the replica as a semipermeable ultrathin polymer membrane.Type: GrantFiled: May 3, 2017Date of Patent: September 1, 2020Assignee: Ultra Small Fibers, LLCInventors: William Hudson Hofmeister, Alexander Yuryevich Terekhov, Jose Lino Vasconcelos da Costa
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Publication number: 20170320057Abstract: A semipermeable ultrathin polymer membrane is a microfluidic device that comprises a substantially optically transparent polymer film having a surface area to thickness ratio of at least 1,000,000:1, and an array of precisely spatially ordered pores of a user-selected diameter defined therethrough. Such membranes can be fabricated by providing a mold having a patterned array of nanoholes femtosecond laser ablated in a surface thereof; applying a first polymer solution onto the mold surface so that the first polymer solution infiltrates the nanoholes; allowing the first polymer solution to dry and form a replica of the mold having a plurality of freestanding nanoneedles extending from a surface of the replica; removing the replica from the mold; coating the replica surface with a second polymer solution; drying the second polymer solution to form a porous polymer film; and dissolving the replica in a solvent to release the film from the replica as a semipermeable ultrathin polymer membrane.Type: ApplicationFiled: May 3, 2017Publication date: November 9, 2017Inventors: William Hudson Hofmeister, Alexander Yuryevich Terekhov, Jose Lino Vasconcelos da Costa
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Publication number: 20160222345Abstract: Embodiments of the presently disclosed subject matter provide biomimetic cell culture substrates comprising highly tunable patterned polymer nanofiber matrices capable of modulating expression of critical self-renewal factors and markers of cell-cell interaction to maintain stemness of human mesenchymal stem cells in vitro. Embodiments of the presently-disclosed subject matter also provide scalable, highly repeatable methods of making biomimetic cell culture substrates by hot pressing thermoplastic polymer films into femtosecond laser-ablated nanopore molds to form patterned polymer nanofiber matrices on flat thermoplastic substrates.Type: ApplicationFiled: February 3, 2016Publication date: August 4, 2016Inventors: William Hudson Hofmeister, Lucas Hofmeister, Alexander Yuryevich Terekhov, Jose Lino Vasconcelos da Costa
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Publication number: 20140308207Abstract: In one aspect, an on-chip microfluidic device (OMD) is provided for microscopic observation. In one embodiment, an on-chip gradient generating device has a silica chip having a cell loading portion configured to load the tissue. A microfluidic channel is formed in the silica chip for a chemoattractant solution having the chemoattractant to flow through, and a plurality of gradient generating ports is formed to connect to the microfluidic channel to the cell loading portion. A chemoattractant supply device is connected to an inlet of the at least one microfluidic channel for supplying the chemoattractant with a constant positive pressure to the chemoattractant solution flowing in the microfluidic channel to create the passive gradient of the chemoattractant in the chemoattractant solution such that the tissue is exposed to the chemoattractant solution having different concentration of the chemoattractant at each gradient generating port.Type: ApplicationFiled: April 16, 2014Publication date: October 16, 2014Inventors: Christopher Janetopoulos, Gus Wright, William Hudson Hofmeister, Jose Lino Vasconcelos da Costa, Alexander Terekhov
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Patent number: 7164468Abstract: This invention relates to a method and an active system for detection and localization of early stage forest fires using lidar. In the simplest configuration the system includes a lidar and a control computer that operates the beam-scanning system and performs automatic recognition of the smoke signature in the lidar signal on the basis of a neural-network algorithm. The scanning procedure is optimized for the given topography and other characteristics of the area under surveillance. The neural network is simulated or implemented as a co-processor. To cover wider areas, several lidar stations may be linked together in a network, which allows simultaneous scanning of the suspicious areas by several neighboring lidars in order to guarantee maximum efficiency and false alarm reduction. The system allows the detection and localization of fires earlier and farther than passive systems, whose sensitivity is lower.Type: GrantFiled: May 31, 2002Date of Patent: January 16, 2007Assignee: Instituto Superior TecnicoInventors: Rui Mario Correia Da Silva Vilar, Fernando Simoes, José Lino Vasconcelos Da Costa, Andrei Borisovich Utkin, Alexander Lavrov
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Publication number: 20040239912Abstract: This invention relates to a method and an active system for detection and localisation of early stage forest fires using lidar. In the simplest configuration the system includes a lidar and a control computer that operates the beam-scanning system and performs automatic recognition of the smoke signature in the lidar signal on the basis of a neural-network algorithm. The scanning procedure is optimised for the given topography and other characteristics of the area under surveillance. The neural network is simulated or implemented as a co-processor. To cover wider areas, several lidar stations may be linked together in a network, which allows simultaneous scanning of the suspicious areas by several neighbouring lidars in order to guarantee maximum efficiency and false alarm reduction. The system allows the detection and localisation of fires earlier and farther than passive systems, whose sensitivity is lower.Type: ApplicationFiled: July 12, 2004Publication date: December 2, 2004Inventors: Rui Mario Correia Da Silva Vilar, Fernando Simoes, Jose Lino Vasconcelos Da Costa, Andrei Borisovich Utkin, Alexander Lavrov