Patents by Inventor Jose M. Castello

Jose M. Castello has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5135943
    Abstract: The 1H-imidazole derivative compound of formula I: ##STR1## and its nontoxic addition salts, particularly the nitrate addition salt, are more effective as antimycotic agents and are unexpectedly safer than the corresponding prior art compounds, especially the compound in which the sulfur atom of the benzothiophene ring of the above compound is replaced by an oxygen atom. Pharmaceutical compositions containing an effective amount of the compound of formula I, e.g. 1 to 5% by weight, in a pharmaceutical carrier are safer, more effective, and, in some cases, more reliable with fewer side effects than currently used antimycotic preparations.
    Type: Grant
    Filed: February 1, 1991
    Date of Patent: August 4, 1992
    Assignee: Ferrer Internacional S.A.
    Inventors: Rafael Foguet, Marcial Moreno, Manuel Raga, Rosa M. Cuberes, Jose M. Castello, Jose A. Ortiz
  • Patent number: 4610998
    Abstract: The invention is concerned with the novel imidazolylethoxy indanes represented by formula (I), ##STR1## or a pharmacologically-acceptable salt thereof, a process for the preparation of them, and a pharmaceutical composition which contains these new compounds as active ingredient and can be used as antithrombotic and platelet antiaggregating agents.
    Type: Grant
    Filed: December 9, 1985
    Date of Patent: September 9, 1986
    Assignee: Ferrer Internacional, S.A.
    Inventors: Rafael Foguet, Ernesto Forne, Jose A. Ortiz, Aurelio Sacristan, Jose M. Castello
  • Patent number: 4600780
    Abstract: New N-cyano-formamidine are disclosed of the formula I: ##STR1## wherein R is 2-[[(5-methyl-1H-Imidazol-4-yl)methyl]thio]ethyl, 2-[[[5-[dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl, 2-[[[2-[(aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]ethyl or 3-[3-(1-piperidinylmethyl)phenoxy]propyl, as well as a process for its production, and pharmaceutical preparations containing the same. The compounds possess histamine--induced gastric acid secretion--inhibiting activity, and are indicated for use in the treatment of peptic ulcer and other pathologies caused or stimulated by gastric acidity.
    Type: Grant
    Filed: March 20, 1984
    Date of Patent: July 15, 1986
    Assignee: Ferrer International, S.A.
    Inventors: Rafael Foguet, Luis Anglada, Manuel M. Raga, Jose A. Ortiz, Aurelio Sacristan, Jose M. Castello