Patents by Inventor Jose Mordoh

Jose Mordoh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8501168
    Abstract: Cell lines, compositions comprising them for the treatment of melanomas, procedures to prepare the compositions, and treatment methods. More particularly, the invention relates to diverse human melanoma cell lines for the treatment of malignant diseases, wherein the cell lines are: (a) Mel-XY1 (deposited at German Collection of Microorganisms and Cell Cultures DSMZ under access number DSM ACC2830), (b) Mel-XY2 (deposited at German Collection of Microorganisms and Cell Cultures DSMZ under access number DSM ACC2831), (c) Mel-XY3 (deposited at German Collection of Microorganisms and Cell Cultures DSMZ under access number DSM ACC2832), (d) Mel-XX4 (deposited at German Collection of Microorganisms and Cell Cultures DSMZ under access number DSM ACC2829), or (e) sub-populations thereof. The cell lines may be irradiated, thus obtaining populations with apoptotic phenotype, and populations with necrotic phenotype of such lines.
    Type: Grant
    Filed: April 11, 2008
    Date of Patent: August 6, 2013
    Assignee: Consejo Nacional de Investigaciones Cientificas y Tecnicas (Conicet)
    Inventors: José Mordoh, María Marcela Barrio, Erika María Von Euw
  • Publication number: 20100183683
    Abstract: Cell lines, compositions comprising them for the treatment of melanomas, procedures to prepare the compositions, and treatment methods. More particularly, the invention relates to diverse human melanoma cell lines for the treatment of malignant diseases, wherein the cell lines are: (a) Mel-XY1 (deposited at German Collection of Microorganisms and Cell Cultures DSMZ under access number DSM ACC2830), (b) Mel-XY2 (deposited at German Collection of Microorganisms and Cell Cultures DSMZ under access number DSM ACC2831), (c) Mel-XY3 (deposited at German Collection of Microorganisms and Cell Cultures DSMZ under access number DSM ACC2832), (d) Mel-XX4 (deposited at German Collection of Microorganisms and Cell Cultures DSMZ under access number DSM ACC2829), or (e) sub-populations thereof. The cell lines may be irradiated, thus obtaining populations with apoptotic phenotype, and populations with necrotic phenotype of such lines.
    Type: Application
    Filed: April 11, 2008
    Publication date: July 22, 2010
    Inventors: José Mordoh, Maria Marcela Barrio, Erika Maria Von Euw
  • Patent number: 7067495
    Abstract: Compositions and methods are described that decrease or inhibit osteonectin activity in tumor cells, including cancer cells. The cells cease to be tumor-like, or become less tumor-like. Pharmaceutical composition and therapies based thereon are also described.
    Type: Grant
    Filed: June 28, 1999
    Date of Patent: June 27, 2006
    Assignee: Fundacion Instituto Leloir
    Inventors: Osvaldo Luis Podhajcer, Maria Fernanda Ledda, Soraya Karina Adris, Alicia Ines Bravo, Jose Mordoh, Yuti Chernajovsky
  • Patent number: 5753229
    Abstract: This invention concerns monoclonal antibodies directed against breast carcinoma cells. Immunoglobulin secreting hybridoma cultures are produced by hybridoma technology using undifferentiated breast cancer cells as antigens for immunization. Hybridomas secreting antibodies highly reactive with tumor proliferating cells are selected. These monoclonal antibodies have particular application in aiding the diagnosis or treatment of cancer.
    Type: Grant
    Filed: November 7, 1994
    Date of Patent: May 19, 1998
    Inventors: Jose Mordoh, Silvia Leis De Cerone, Osvaldo Luis Podhajcer, Alicia Ines Bravo