Patents by Inventor Josef Parvizi
Josef Parvizi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230346884Abstract: Methods of modulating dissociative and associative states in a subject are provided. In particular, neuromodulation of rhythmic neural activity in the posteromedial cortex can be used to induce or inhibit dissociative states in a subject.Type: ApplicationFiled: August 9, 2021Publication date: November 2, 2023Inventors: Ethan B. Richman, Josef Parvizi, Jaimie M. Henderson, Paul Nuyujukian, Felicity Gore, Isaac V. Kauvar, Sam Vesuna, Karl A. Deisseroth
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Patent number: 11471088Abstract: A handheld device for sonifying electrical signals obtained from a subject is provided. The device can utilize at least one of several operations including (but not limited) digitizing signals from electrodes, adjusting the signals based on accelerometer input, filtering the signals, conditioning the signals according to conditioning parameters, modulating the signal according to sound synthesis parameters, and generating sound from the representations of the signals to accomplish sonification. The device can include an analog-to-digital (A/D) converter to digitize the one or more electrical signals and a processor that receives the one or more digitized electrical signals and produces a representation of an acoustic signal. The device further includes a speaker system that sonifies the representation of the acoustic signal.Type: GrantFiled: May 19, 2016Date of Patent: October 18, 2022Assignees: The Board of Trustees of the Leland Stanford Junior University, CeribellInventors: Josef Parvizi, Christopher D. Chafe, Xingjuan Chao, Ronald C. Eddington, Jr.
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Publication number: 20220117536Abstract: An electrode carrier system includes one or more electrode assemblies having an electrode body. One or more tubular members extend from the electrode body and define a lumen terminating in a distal opening. The electrode assemblies carry a reservoir containing a conductive fluid or gel. The reservoir is in fluid communication with the lumens in the tubular members, and the electrode assemblies are typically supported on a backing which may optionally be configured as a headband. Systems are for tracking patient movement may be used in combination with the electrode carrier system.Type: ApplicationFiled: December 28, 2021Publication date: April 21, 2022Inventors: Josef PARVIZI, Xingjuan CHAO, Bradley G. BACHELDER, Raymond WOO, Mathew A. HERRON, Vahid SAADAT, Alexander M. GRANT, Jianchun YI
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Publication number: 20220117535Abstract: An electrode carrier system includes one or more electrode assemblies having an electrode body. One or more tubular members extend from the electrode body and define a lumen terminating in a distal opening. The electrode assemblies carry a reservoir containing a conductive fluid or gel. The reservoir is in fluid communication with the lumens in the tubular members, and the electrode assemblies are typically supported on a backing which may optionally be configured as a headband. Systems are for tracking patient movement may be used in combination with the electrode carrier system.Type: ApplicationFiled: December 28, 2021Publication date: April 21, 2022Inventors: Josef PARVIZI, Xingjuan CHAO, Bradley G. BACHELDER, Raymond WOO, Mathew A. HERRON, Vahid SAADAT, Alexander M. GRANT, Jianchun YI
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Publication number: 20220031248Abstract: Systems, devices, and methods are provided to assess connection quality between the electrodes of a bioelectrical signal measurement and/or electrical stimulation device and the tissue, typically skin, of the subject. A test signal is provided to a first electrode, voltage differences between the first electrode and additional electrodes are determined, an impedance of the first electrode is determined based on the voltages differences, and the determined impedance indicates connection quality. This process is typically repeated for all of the electrodes to determine connection quality. The user or subject can be alerted if the connection quality is poor, and the bioelectrical signal that is recorded can be provided with data points indicating connection quality during the signal recording.Type: ApplicationFiled: March 16, 2021Publication date: February 3, 2022Inventors: Alexander M. GRANT, Jianchun YI, Bradley G. BACHELDER, Raymond WOO, Josef PARVIZI, Xingjuan CHAO
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Publication number: 20210267539Abstract: Systems and methods for sonifying electrical signals obtained from a living subject, particularly EEG signals, are disclosed. A time-domain signal representing the activity of an organ is obtained. A voltage of the time-domain signal over a time block is determined. An acoustic signal based on the time-domain signal over the time block is produced. The acoustic signal comprises one or more audibly discernible variations representative of the activity of the organ. If the determined voltage is over a threshold voltage, the time-domain signal is squelched over at least a portion of the time-block as the acoustic signal is produced. The time-domain signal can be squelched by ramping down the signal as an input to produce the acoustic signal. The frequency spectrum of the acoustic signal can also be adjusted as it is produced, such as by flattening the signal and/or attenuating high frequencies along the frequency spectrum of the signal.Type: ApplicationFiled: October 28, 2020Publication date: September 2, 2021Inventors: Alexander GRANT, Chris CHAFE, Josef PARVIZI, Jianchun YI, Raymond WOO, Xingjuan CHAO
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Patent number: 11045150Abstract: A digital processor system having one or more processors and memory obtains a time-domain signal representing brain activity, the time-domain signal having a time varying signal value. The system concurrently generates a set of acoustic parameters, including a plurality of time-varying acoustic parameters, where one or more of the plurality of time-varying acoustic parameters is modulated in accordance with at least the signal value of the time-domain signal. The system combines the concurrently generated set of acoustic parameters to produce a representation of an acoustic signal corresponding to the time-domain signal, where the acoustic signal, in audible form, manifests one or more audibly discernible variations across a plurality of stages of a brain activity event.Type: GrantFiled: October 8, 2018Date of Patent: June 29, 2021Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Christopher D. Chafe, Josef Parvizi
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Publication number: 20210128044Abstract: An electrode carrier system includes one or more electrode assemblies having an electrode body. One or more tubular members extend from the electrode body and define a lumen terminating in a distal opening. The electrode assemblies carry a reservoir containing a conductive fluid or gel. The reservoir is in fluid communication with the lumens in the tubular members, and the electrode assemblies are typically supported on a backing which may optionally be configured as a headband. Systems are for tracking patient movement may be used in combination with the electrode carrier system.Type: ApplicationFiled: November 4, 2020Publication date: May 6, 2021Inventors: Josef Parvizi, Xingjuan Chao, Bradley G. Bachelder, Raymond Woo, Mathew A. Herron, Vahid Saadat, Alexander M. Grant, Jianchun Yi
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Patent number: 10980480Abstract: Systems, devices, and methods are provided to assess connection quality between the electrodes of a bioelectrical signal measurement and/or electrical stimulation device and the tissue, typically skin, of the subject. A test signal is provided to a first electrode, voltage differences between the first electrode and additional electrodes are determined, an impedance of the first electrode is determined based on the voltages differences, and the determined impedance indicates connection quality. This process is typically repeated for all of the electrodes to determine connection quality. The user or subject can be alerted if the connection quality is poor, and the bioelectrical signal that is recorded can be provided with data points indicating connection quality during the signal recording.Type: GrantFiled: March 25, 2019Date of Patent: April 20, 2021Assignee: CeriBell, Inc.Inventors: Alexander M. Grant, Jianchun Yi, Bradley G. Bachelder, Raymond Woo, Josef Parvizi, Xingjuan Chao
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Publication number: 20210085235Abstract: The present disclosure provides systems and methods for seizure detection. The method for seizure detection may include receiving a plurality of electroencephalography (EEG) signals over a plurality of channels for a subject, preprocessing the plurality of EEG signals by segmenting the plurality of EEG signals for each channel into a plurality of temporal data segments, extracting a plurality of features from each temporal data segment for each channel, and applying a machine learning algorithm to the plurality of features to perform a seizure binary classification for each temporal data segment for each channel. A control policy may be employed to determine a seizure burden on the aggregated seizure binary classifications. When the seizure burden is equal to or exceeds a threshold, a notification may be generated. The notification may be usable by a healthcare practitioner to assess whether the subject may be at risk of having a seizure.Type: ApplicationFiled: July 8, 2020Publication date: March 25, 2021Inventors: Baharan Kamousi, Mehdi Hajinoroozi, Suganya Karunakaran, Alexander M. Grant, Jianchun Yi, Raymond Woo, Josef Parvizi, Xingjuan Chao
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Patent number: 10888240Abstract: An electrode carrier system includes one or more electrode assemblies having an electrode body. One or more tubular members extend from the electrode body and define a lumen terminating in a distal opening. The electrode assemblies carry a reservoir containing a conductive fluid or gel. The reservoir is in fluid communication with the lumens in the tubular members, and the electrode assemblies are typically supported on a backing which may optionally be configured as a headband. Systems are for tracking patient movement may be used in combination with the electrode carrier system.Type: GrantFiled: October 13, 2017Date of Patent: January 12, 2021Assignee: CeriBell, Inc.Inventors: Josef Parvizi, Xingjuan Chao, Bradley G. Bachelder, Raymond Woo, Mathew A. Herron, Vahid Saadat, Alexander M. Grant, Jianchun Yi
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Patent number: 10849553Abstract: Systems and methods for sonifying electrical signals obtained from a living subject, particularly EEG signals, are disclosed. A time-domain signal representing the activity of an organ is obtained. A voltage of the time-domain signal over a time block is determined. An acoustic signal based on the time-domain signal over the time block is produced. The acoustic signal comprises one or more audibly discernible variations representative of the activity of the organ. If the determined voltage is over a threshold voltage, the time-domain signal is squelched over at least a portion of the time-block as the acoustic signal is produced. The time-domain signal can be squelched by ramping down the signal as an input to produce the acoustic signal. The frequency spectrum of the acoustic signal can also be adjusted as it is produced, such as by flattening the signal and/or attenuating high frequencies along the frequency spectrum of the signal.Type: GrantFiled: March 27, 2019Date of Patent: December 1, 2020Assignee: CeriBell, Inc.Inventors: Alexander Grant, Chris Chafe, Josef Parvizi, Jianchun Yi, Raymond Woo, Xingjuan Chao
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Publication number: 20200305786Abstract: Systems and methods for sonifying electrical signals obtained from a living subject, particularly EEG signals, are disclosed. A time-domain signal representing the activity of an organ is obtained. A voltage of the time-domain signal over a time block is determined. An acoustic signal based on the time-domain signal over the time block is produced. The acoustic signal comprises one or more audibly discernible variations representative of the activity of the organ. If the determined voltage is over a threshold voltage, the time-domain signal is squelched over at least a portion of the time-block as the acoustic signal is produced. The time-domain signal can be squelched by ramping down the signal as an input to produce the acoustic signal. The frequency spectrum of the acoustic signal can also be adjusted as it is produced, such as by flattening the signal and/or attenuating high frequencies along the frequency spectrum of the signal.Type: ApplicationFiled: March 27, 2019Publication date: October 1, 2020Inventors: Alexander GRANT, Chris CHAFE, Josef PARVIZI, Jianchun YI, Raymond WOO, Xingjuan CHAO
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Patent number: 10743809Abstract: The present disclosure provides systems and methods for seizure detection. The method for seizure detection may include receiving a plurality of electroencephalography (EEG) signals over a plurality of channels for a subject, preprocessing the plurality of EEG signals by segmenting the plurality of EEG signals for each channel into a plurality of temporal data segments, extracting a plurality of features from each temporal data segment for each channel, and applying a machine learning algorithm to the plurality of features to perform a seizure binary classification for each temporal data segment for each channel. A control policy may be employed to determine a seizure burden on the aggregated seizure binary classifications. When the seizure burden is equal to or exceeds a threshold, a notification may be generated. The notification may be usable by a healthcare practitioner to assess whether the subject may be at risk of having a seizure.Type: GrantFiled: September 20, 2019Date of Patent: August 18, 2020Assignee: CeriBell, Inc.Inventors: Baharan Kamousi, Mehdi Hajinoroozi, Suganya Karunakaran, Alexander Grant, Jianchun Yi, Raymond Woo, Josef Parvizi, Xingjuan Chao
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Publication number: 20200138320Abstract: A handheld device for sonifying electrical signals obtained from a subject is provided. The device can utilize at least one of several operations including (but not limited) digitizing signals from electrodes, adjusting the signals based on accelerometer input, filtering the signals, conditioning the signals according to conditioning parameters, modulating the signal according to sound synthesis parameters, and generating sound from the representations of the signals to accomplish sonification. The device can include an analog-to-digital (A/D) converter to digitize the one or more electrical signals and a processor that receives the one or more digitized electrical signals and produces a representation of an acoustic signal. The device further includes a speaker system that sonifies the representation of the acoustic signal.Type: ApplicationFiled: December 2, 2019Publication date: May 7, 2020Inventors: Josef Parvizi, Christopher D. Chafe, Xinghuan Chao, Ronald C. Eddington, JR.
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Publication number: 20190343462Abstract: Systems, devices, and methods are provided to assess connection quality between the electrodes of a bioelectrical signal measurement and/or electrical stimulation device and the tissue, typically skin, of the subject. A test signal is provided to a first electrode, voltage differences between the first electrode and additional electrodes are determined, an impedance of the first electrode is determined based on the voltages differences, and the determined impedance indicates connection quality. This process is typically repeated for all of the electrodes to determine connection quality. The user or subject can be alerted if the connection quality is poor, and the bioelectrical signal that is recorded can be provided with data points indicating connection quality during the signal recording.Type: ApplicationFiled: March 25, 2019Publication date: November 14, 2019Inventors: Alexander M. GRANT, Jianchun YI, Bradley G. BACHELDER, Raymond WOO, Josef PARVIZI, Xingjuan CHAO
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Patent number: 10285646Abstract: Systems, devices, and methods are provided to assess connection quality between the electrodes of a bioelectrical signal measurement and/or electrical stimulation device and the tissue, typically skin, of the subject. A test signal is provided to a first electrode, voltage differences between the first electrode and additional electrodes are determined, an impedance of the first electrode is determined based on the voltages differences, and the determined impedance indicates connection quality. This process is typically repeated for all of the electrodes to determine connection quality. The user or subject can be alerted if the connection quality is poor, and the bioelectrical signal that is recorded can be provided with data points indicating connection quality during the signal recording.Type: GrantFiled: February 27, 2018Date of Patent: May 14, 2019Assignee: CeriBell, Inc.Inventors: Alexander M. Grant, Jianchun Yi, Bradley G. Bachelder, Raymond Woo, Josef Parvizi, Xingjuan Chao
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Patent number: 10136862Abstract: A digital processor system having one or more processors and memory obtains a time-domain signal representing brain activity, the time-domain signal having a time varying signal value. The system concurrently generates a set of acoustic parameters, including a plurality of time-varying acoustic parameters, where one or more of the plurality of time-varying acoustic parameters is modulated in accordance with at least the signal value of the time-domain signal. The system combines the concurrently generated set of acoustic parameters to produce a representation of an acoustic signal corresponding to the time-domain signal, where the acoustic signal, in audible form, manifests one or more audibly discernible variations across a plurality of stages of a brain activity event.Type: GrantFiled: May 30, 2013Date of Patent: November 27, 2018Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Christopher D. Chafe, Josef Parvizi
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Publication number: 20180049661Abstract: An electrode carrier system includes one or more electrode assemblies having an electrode body. One or more tubular members extend from the electrode body and define a lumen terminating in a distal opening. The electrode assemblies carry a reservoir containing a conductive fluid or gel. The reservoir is in fluid communication with the lumens in the tubular members, and the electrode assemblies are typically supported on a backing which may optionally be configured as a headband. Systems are for tracking patient movement may be used in combination with the electrode carrier system.Type: ApplicationFiled: October 13, 2017Publication date: February 22, 2018Applicant: CeriBell, Inc.Inventors: Josef Parvizi, Xingjuan Chao, Bradley G. Bachelder, Raymond Woo, Mathew A. Herron, Vahid Saadatt, Alexander M. Grant, Jianchum Yi
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Patent number: 9888884Abstract: A digital processor system obtains at least one time-domain signal representing brain activity and at least one time-domain signal representing heart activity, each having a time-varying signal value. The system produces representations of a plurality of acoustic signals, each of which corresponds to a respective time-domain signal and is produced by concurrently generating a plurality of acoustic parameters, including a plurality of time-varying acoustic parameters. One or more of the plurality of time-varying acoustic parameters is modulated in accordance with at least the signal value of the respective time-domain signal. Each representation of an acoustic signal of the plurality of acoustic signals is further produced by combining the concurrently generated plurality of acoustic parameters to produce the representation of the acoustic signal corresponding to the respective time-domain signal.Type: GrantFiled: December 1, 2014Date of Patent: February 13, 2018Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Christopher D. Chafe, Josef Parvizi