Abstract: The embodiments disclosed herein utilized RNA targeting effectors to provide a robust CRISPR-based diagnostic with attomolar sensitivity. Embodiments disclosed herein can detect broth DNA and RNA with comparable levels of sensitivity and can differentiate targets from non-targets based on single base pair differences. Moreover, the embodiments disclosed herein can be prepared in freeze-dried format for convenient distribution and point-of-care (POC) applications. Such embodiments are useful in multiple scenarios in human health including, for example, viral detection, bacterial strain typing, sensitive genotyping, and detection of disease-associated cell free DNA.

Abstract: A hand sanitizing device described herein allows users to sanitize and/or disinfect their hands by bathing them in ultraviolet light. The hand sanitizing device may comprise a cabinet that comprises one or more cavities for a user's hands. The one or more cavities may comprise a sensor to detect a user's hands, a controller to send signals to a plurality of ultraviolet lights, and a plurality of ultraviolet lights. Based on a determination that the user has placed their hands in the one or more cavities, the plurality of ultraviolet lights may be illuminated to sanitize and/or disinfectant the user's hands. When the user has removed their hands from the one or more cavities, the plurality of ultraviolet lights may be turned off. By using ultraviolet light, the hand sanitizing device may reduce the spread of infectious diseases and waste consumption associated with bathroom usage.

Abstract: Aspects described herein include a method comprising receiving one or more sensor signals from one or more sensors that are worn by a wearer, and determining, based on the one or more sensor signals, one or more poses of a leg of the wearer during motion. The method further comprises controlling, based on the one or more poses, a pressure of one or more actuatable components to adjust the leg toward a target pose during the motion. The one or more actuatable components are worn on one or both of the leg and a foot of the wearer.

Abstract: The embodiments disclosed herein utilized RNA targeting effectors to provide a robust CRISPR-based diagnostic with attomolar sensitivity. Embodiments disclosed herein can detect both DNA and RNA with comparable levels of sensitivity and can differentiate targets from non-targets based on single base pair differences. Moreover, the embodiments disclosed herein can be prepared in freeze-dried format for convenient distribution and point-of-care (POC) applications. Such embodiments are useful in multiple scenarios in human health including, for example, viral detection, bacterial strain typing, sensitive genotyping, and detection of disease-associated cell free DNA.

Abstract: A method of removing trapped hydrocarbons from pipework, the pipework comprising a through pipe (1) extending from an inlet to an outlet, and at least one up-pipe (2a, 2b) extending upwardly from the through pipe. The method comprises: flushing the through pipe with a water-based liquid (6) which has a density less than hydrocarbons; wherein the water-based liquid comprises a plurality of rigid containers, such as microspheres, the rigid containers each having a sealed void containing a gas. in this way, hydrocarbons in the up-pipes may be removed without hot-tapping them. The flushing may be performed by directing pipeline pigs (5a, 5b) in front of and behind the water-based liquid. The pigs may be a cross-linked gel, based pipeline pig with elastomeric properties. A kit of parts for such a method is also disclosed.

Abstract: The embodiments disclosed herein utilized RNA targeting effectors to provide a robust CRISPR-based diagnostic with attomolar sensitivity. Embodiments disclosed herein can detect both DNA and RNA with comparable levels of sensitivity and can differentiate targets from non-targets based on single base pair differences. Moreover, the embodiments disclosed herein can be prepared in freeze-dried format for convenient distribution and point-of-care (POC) applications. Such embodiments are useful in multiple scenarios in human health including, for example, viral detection, bacterial strain typing, sensitive genotyping, and detection of disease-associated cell free DNA.

Abstract: The embodiments disclosed herein utilized RNA targeting effectors to provide a robust CRISPR-based diagnostic with attomolar sensitivity. Embodiments disclosed herein can detect broth DNA and RNA with comparable levels of sensitivity and can differentiate targets from non-targets based on single base pair differences. Moreover, the embodiments disclosed herein can be prepared in freeze-dried format for convenient distribution and point-of-care (POC) applications. Such embodiments are useful in multiple scenarios in human health including, for example, viral detection, bacterial strain typing, sensitive genotyping, and detection of disease-associated cell free DNA.

Abstract: The disclosure provides at least an apparatus, system and method for providing a flexible planar inductive coil, such as may be embedded in a product. The apparatus, system and method may include at least one conformable substrate, and a matched function ink set, printed onto at least one substantially planar face of the at least one substrate. This printing may form at least one layer of additive conductive traces capable of receiving current flow from at least one source and layered into successive ones of the conductive traces about a center axis within a plane of the at least one conformable substrate.

Abstract: The embodiments disclosed herein utilized RNA targeting effectors to provide a robust CRISPR-based diagnostic with attomolar sensitivity. Embodiments disclosed herein can detect broth DNA and RNA with comparable levels of sensitivity and can differentiate targets from non-targets based on single base pair differences. Moreover, the embodiments disclosed herein can be prepared in freeze-dried format for convenient distribution and point-of-care (POC) applications. Such embodiments are useful in multiple scenarios in human health including, for example, viral detection, bacterial strain typing, sensitive genotyping, and detection of disease-associated cell free DNA.

Abstract: The disclosure provides at least an apparatus, system and method for providing a flexible planar inductive coil, such as may be embedded in a product. The apparatus, system and method may include at least one conformable substrate, and a matched function ink set, printed onto at least one substantially planar face of the at least one substrate. This printing may form at least one layer of additive conductive traces capable of receiving current flow from at least one source and layered into successive ones of the conductive traces about a center axis within a plane of the at least one conformable substrate.

Abstract: A rechargeable battery cell includes an electrode and an ion exchange material arranged to define an interpenetrating interface with at least a portion of the electrode. Providing an interpenetration interface in intimate contact can include completely or partially embedding the electrode in the ion exchange material, or alternatively, surrounding the electrode or discrete portions of the electrode with a thin film of ion exchange material. In one embodiment, electrodes can be particles fully or partially embedded, coated with, or partially contacting ion exchange material.

Abstract: The method includes a step of introducing into the reservoir, via a well, a mixture comprising a scale inhibitor, a first scale precursor and a second scale precursor. The first and second scale precursors can react together to form scale. The first scale precursor may be an ammonium salt. The method can further comprise a step of stopping the introduction into the reservoir of the mixture and shutting in the well for 2-24 hours, and a step of introducing into the reservoir a further mixture comprising a scale inhibitor, a first and second scale precursor which can react together to form scale. The steps of stopping and resuming the introduction of mixtures may be repeated at least once. The components of the mixtures may be provided as concentrated solutions and diluted in a stream of water prior to being introduced into the reservoir. The method provides an effective way of generating a barrier to fluid flow in a reservoir. The method may be a method of abandoning an entire well in a reservoir.

Abstract: A method of a bandoning a well in a reservoir. The method including the step of forming a scale in the reservoir by introducing into the reservoir a first solution comprising a first scale precursor and a second solution comprising a second scale precursor and a scale inhibitor. The first solution and second solution are able to react together to form the scale. The method further includes the step of at least partially filling the well with cement.

Abstract: An electronic messaging system and method with reduced traceability by separation of display of media component of message content and header information. An electronic message having an identifier of a recipient and a message content including an image media component is received at a server from a sending user device at which a display for associating the media component with the electronic message is provided without displaying the identifier of a recipient with the media component such that a single screen capture of the identifier of a recipient and the media component is prevented. The electronic message including an identifier of a sending user is transmitted to a recipient user device at which a display presenting the media component is provided without displaying the identifier of a sending user such that a single screen capture of both the identifier of a sending user and the media component is prevented.

Abstract: Disclosed are various embodiments for facilitating item bundles. An item bundle includes more than one item from an item universe that can be bundled together. For example, in an electronic marketplace, two items can be linked together as a bundle that is sold. An order document can be created that includes a reference to the item bundle that is associated with an entry for each of the items in the bundle.

Abstract: An electronic messaging system and method with reduced traceability by separation of display of media component of message content and header information. An electronic message having an identifier of a recipient and a message content including an image media component is received at a server from a sending user device at which a display for associating the media component with the electronic message is provided without displaying the identifier of a recipient with the media component such that a single screen capture of the identifier of a recipient and the media component is prevented. The electronic message including an identifier of a sending user is transmitted to a recipient user device at which a display presenting the media component is provided without displaying the identifier of a sending user such that a single screen capture of both the identifier of a sending user and the media component is prevented.

Abstract: An electronic messaging method for reply messaging using a pen digitizer and a reply ID. A reply ID is utilized to identify a sender of a message and a pen digitizer is utilized to enter a message body and message header having a recipient address. The reply ID is deleted prior to entry of the reply message and the reply message is transmitted over a wired local area network to a sender workstation.

Abstract: Provided herein is a nucleic acid detection system comprising: a CRISPR system comprising an effector protein and one or more guide RNAs designed to bind to corresponding target molecules; an RNA-based masking construct; and optionally, nucleic acid amplification reagents to amplify target RNA molecules in a sample. In another aspect, the embodiments provide a polypeptide detection system comprising: a CRISPR system comprising an effector protein and one or more guide RNAs designed to bind a trigger RNA, an RNA-based masking construct; and one or more detection aptamers comprising a masked RNA polymerase promoter binding site or a masked primer binding site. In some embodiments, the system may be used to detect viruses in samples.

Abstract: The method includes a step of introducing into the reservoir, via a well, a mixture comprising a scale inhibitor, a first scale precursor and a second scale precursor. The first and second scale precursors can react together to form scale. The first scale precursor may be an ammonium salt. The method can further comprise a step of stopping the introduction into the reservoir of the mixture and shutting in the well for 2-24 hours, and a step of introducing into the reservoir a further mixture comprising a scale inhibitor, a first and second scale precursor which can react together to form scale. The steps of stopping and resuming the introduction of mixtures may be repeated at least once. The components of the mixtures may be provided as concentrated solutions and diluted in a stream of water prior to being introduced into the reservoir. The method provides an effective way of generating a barrier to fluid flow in a reservoir. The method may be a method of abandoning an entire well in a reservoir.

Abstract: A method of a bandoning a well in a reservoir. The method including the step of forming a scale in the reservoir by introducing into the reservoir a first solution comprising a first scale precursor and a second solution comprising a second scale precursor and a scale inhibitor. The first solution and second solution are able to react together to form the scale. The method further includes the step of at least partially filling the well with cement.