Abstract: Herein is provided a recombinant tumor-selective viral particle comprising a nucleic acid encoding a recombinant polypeptide for directing an extracellular vesicle (EV) to at least one target cell, said recombinant polypeptide comprising: at least one targeting moiety for directing said EV to said at least one target molecule expressed by said at least one target cell; at least one EV-anchoring polypeptide; and at least one intravesicular polypeptide. The viral particle may be from an oncolytic viruses. Recombinant polypeptides for programming EVs to target particular molecules are also provided. Also described are therapeutic EVs for delivering payload polypeptides (and/or cargo molecules) to target cells, e.g., in vaccine or cell-free “CAR-T”-like applications, along with EVs for recruiting immune cells to target cells in EV-mediated BiTE -like applications. Oncolytic viruses may also be engineered to infect tumor cells and shed programmed EVs, yielding additional therapeutic effects.

Abstract: A telecommunications gateway allows packets to be sent over a TDM system and allows TDM traffic to be sent over a packet switched network. The gateway is a universal port that includes a plurality of Digital Signal Processors (DSPs) that are controlled by software. The controlling software determines what single function the DSP will perform over multiple channels. Each DSP handles multiple channels, however, each DSP is restricted such that all of its multiple channels are permitted to handle the telecommunications traffic according to one signaling protocol.

Abstract: A telecommunications gateway allows packets to be sent over a TDM system and allows TDM traffic to be sent over a packet switched network. The gateway is a universal port that includes a plurality of Digital Signal Processors (DSPs) that are controlled by software. The controlling software determines what single function the DSP will perform over multiple channels. Each DSP handles multiple channels, however, each DSP is restricted such that all of its multiple channels are permitted to handle the telecommunications traffic according to one signaling protocol.

Abstract: In a system in which user equipment is connected to a packet network and a speech recognition application server is also connected to the packet network for performing speech recognition on speech data from the user equipment, a speech recognition system selectively performs feature extraction at a user end before transmitting speech data to be recognized. The feature extraction is performed only for speech which is to be recognized.

Abstract: A technique for use in communications systems utilizing busy and idle modes. In the busy mode, symbols representative of data are transmitted to system end users. In the idle mode, during which no data is communicated to end users, idle mode symbols are transmitted. Such idle mode symbols are not used to represent data and are only transmitted during the idle mode. Advantageously, such idle mode symbols maintain adaptive apparatus, such as AGC circuits, NEXT cancellers and equalizers, in their properly converged state. In the disclosed embodiment, the idle mode symbols are the innermost symbols in a signal constellation and transition from the idle to busy mode is represented by the transmission of a predetermined number of outermost symbols in the signal constellation. Use of such symbols for idle-to-busy mode transitions advantageously provides ready detection of such transitions. In addition, use of the innermost symbols for the idle mode reduces spectral emission and crosstalk.

Abstract: A communication system controller is operable under program calls from two memories which are independently changeable. A first memory includes a group of hardware-dependent programs and a second memory includes a group of hardware-independent programs. Calls are initiated by programs resident on the first memory to an interface program resident on the second memory at an address known to programs of the first memory. This interface program call includes an argument indentifyng the function program to be called. The interface program uses the argument to determine the location of the function program from a program table and then transfers control to the function program.