Patents by Inventor Joseph Bondy-Denomy

Joseph Bondy-Denomy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INHIBITORS OF CRISPR-CAS9
    Publication number: 20230287058
    Abstract: Cas9-inhibiting polypeptide compositions and methods are provided.
    Type: Application
    Filed: September 28, 2022
    Publication date: September 14, 2023
    Inventors: Joseph Bondy-Denomy, Benjamin Rauch
  • BROAD SPECTRUM INHIBITORS OF CRISPR-CAS9
    Publication number: 20220380421
    Abstract: The present disclosure provides Cas9-inhibiting polypeptides and polynucleotides, and methods of using the same to inhibit Cas9 in cells.
    Type: Application
    Filed: May 2, 2022
    Publication date: December 1, 2022
    Inventors: Joseph Bondy-Denomy, Caroline Mahendra
  • CRISPR-CAS3 FOR MAKING GENOMIC DELETIONS AND INDUCING RECOMBINATION
    Publication number: 20220356470
    Abstract: The present disclosure provides methods and compositions for generating deletions, inducing recombination, and for modulating gene expression in cells using type I CRISPR-Cas systems.
    Type: Application
    Filed: June 19, 2020
    Publication date: November 10, 2022
    Applicant: The Regents of the University of California
    Inventors: Lina Maria Leon, Balint Csorgo, Joseph Bondy-Denomy
  • Inhibitors of CRISPR-Cas9
    Patent number: 11485760
    Abstract: Cas9-inhibiting polypeptide compositions and methods are provided.
    Type: Grant
    Filed: November 16, 2017
    Date of Patent: November 1, 2022
    Assignee: The Regents of the University of California
    Inventors: Joseph Bondy-Denomy, Benjamin Rauch
  • ANTI-CRISPR INHIBITORS
    Publication number: 20220243213
    Abstract: The present disclosure provides compositions and methods for introducing or enhancing Aca activity in prokaryotic cells. The provided compositions and methods can be used to inhibit Acr activity in prokaryotic cells, thereby enhancing endogenous or exogenous CRISPR-Cas activity. Cells, polynucleotides, plasmids, phage, and other elements for practicing the present methods are also provided.
    Type: Application
    Filed: May 29, 2020
    Publication date: August 4, 2022
    Inventors: Joseph Bondy-Denomy, Adair Borges, Jenny Yujie Zhang, Beatriz Osuna, SR., Sabrina Stanley, Alan Davidson
  • PROTEINS THAT INHIBIT CAS12A (CPF1), A CRIPR-CAS NUCLEASE
    Publication number: 20210363206
    Abstract: Cas12a-inhibiting polypeptides and methods of their use are provided.
    Type: Application
    Filed: June 17, 2019
    Publication date: November 25, 2021
    Inventors: Nicole Blackburn-Marino, Joseph Bondy-Denomy, Kyle E. Watters, Jennifer A. Doudna
  • INHIBITORS OF CRISPR-CAS9
    Publication number: 20200087354
    Abstract: Cas9-inhibiting polypeptide compositions and methods are provided.
    Type: Application
    Filed: November 16, 2017
    Publication date: March 19, 2020
    Inventors: Joseph Bondy-Denomy, Benjamin Rauch