Abstract: A drug delivery device for administering a drug is presented having a body adapted to retain a cartridge containing a drug, at least one electrical unit and a port for electrically contacting the electrical unit, an adapter for attaching an injection needle to the drug delivery device, a safety mechanism arranged to prevent contacting the electrical unit through the port whilst an injection needle is in fluid communication with the cartridge and arranged to prevent establishing a fluid communication between an injection needle and the cartridge whilst the port is configured to allow contacting the electrical unit.

Abstract: The present disclosure is directed to a spring arrangement for use in a drug delivery device and a drug delivery device including such a spring arrangement. The spring arrangement includes a clutch spring which is located axially interposed between a stationary housing component and an axially movable sleeve. The sleeve includes clutch features adapted to engage corresponding clutch features of a clutch element. The clutch spring biases the clutch features and the corresponding clutch features into engagement. The sleeve is coupled to a button such that upon actuation of the button the sleeve is translated against the bias of the clutch spring from a proximal position in which the sleeve is rotationally locked to the housing component into a distal position in which the sleeve is rotationally un-locked from the housing component. Upon release of the button the clutch spring translates the sleeve and the button into the proximal position.

Abstract: There is disclosed in one example a computing apparatus, including: a hardware platform; and a service chain pre-placement analyzer to operate on the hardware platform and configured to: receive a total utility input for a service chain placement; predict a mobility pattern for the service chain placement; and compute an average utility for the service chain placement, wherein the average utility is a product of the total utility and the mobility pattern.

Abstract: A data collection device for attachment to an injection device, such as an injector pen, includes a sensor arrangement to detect movement of a movable component of the injection device relative to the data collection device during delivery of a medicament by the injection device, and a processor arrangement configured to, based on said detected movement, determine a medicament dosage administered by the injection device. The processor arrangement may monitor the time that has elapsed since the medicament dosage was administered, and control a display to show the medicament dosage and elapsed time to provide a memory aid to the user. In an example embodiment, the sensor arrangement includes an optical encoder and the movable component includes a plurality of light barrier formations. The movable component may be a number sleeve that provides a visual indication of a dose programmed into the injection device.

Abstract: Methods, systems, and storage media for telemetry adaptation are disclosed herein. In an embodiment, a networking device may include a data collector agent module to receive measurement data from measurement sources according to an initial telemetry policy and to provide the measurement data to the one or more servers of the monitoring system. The networking device may include an anomaly detection module to receive measurement data from the data collector agent module, to detect an anomaly in the measurement data, and to provide an indication of the anomaly to the data collector agent module for the data collector agent module to provide a first modified telemetry policy for the measurement sources.

Abstract: The invention relates to an electronic module for recording information of a drug delivery device, the electronic module comprising at least one connector, wherein at least one connector is adapted to be connected to a port of the drug delivery device and wherein at least one connector is adapted to be connected to a port of a computer. Furthermore, the invention relates to a drug delivery device, comprising a port for connecting to the connector of the electronic module.

Abstract: An aerosol dispenser comprising a pressurised aerosol can and a closure comprising an aerosol valve held within a retention chassis, the retention chassis being associated with a flexible sealing collar designed to radially surround the retention chassis and to seal against the edge of an opening in the aerosol can, wherein the retention chassis is axially moveable relative to the sealing collar and wherein the sealing collar is of outer diameter greater than the inner diameter of the opening in the aerosol can and is sufficiently flexible to flex through the opening in the aerosol can when the retention chassis is in a first axial position relative to the sealing collar and wherein the sealing collar is firmly held against the edge of the opening in the aerosol can when the retention chassis is in a second axial position relative to the sealing collar.

Abstract: The disclosure refers to a handheld injection device comprising a housing, a dose indicator positioned within and axially constrained to the housing and rotatable with respect to the housing during dose setting and during dose dispensing, a gauge element, which is at least partly interposed between the housing and the dose indicator, wherein the gauge element is axially guided within the housing and in threaded engagement with the dose indicator such that rotation of the dose indicator causes an axial displacement of the gauge element (80; 490). A contrast element having a first marking is provided and at least a region of the gauge element is provided with a second marking, with the first marking and/or the second marking being visible through a first window or aperture in the housing depending on the axial position of the gauge element within the housing.

Abstract: The invention relates to an electronic module for recording information of a drug delivery device, the electronic module comprising at least one connector, wherein at least one connector is adapted to be connected to a port of the drug delivery device and wherein at least one connector is adapted to be connected to a port of a computer. Furthermore, the invention relates to a drug delivery device, comprising a port for connecting to the connector of the electronic module.

Abstract: A drug delivery device for selecting and dispensing a number of user variable doses of a medicament includes a housing having an opening, a dose selector operable to set a dose by rotation relative to the housing, a release member controlling movement of a piston in a dispensing direction, and a display comprising a units number wheel and a tens number wheel which are coupled to each other such that a continuous rotation of the units number wheel is translated into an intermittent rotary motion of the tens number wheel. The release member rotates, during dose dispensing, an angle corresponding to the dose set by the dose selector, thereby allowing a piston to move in a dispensing direction.

Abstract: A coded cartridge holder for use with a drug delivery device is provided. The cartridge holder includes a fastener that becomes operative based in part on a length of a cartridge or a diameter of the cartridge. In one embodiment, the cartridge holder is coupled to the drug delivery device. The cartridge holder comprises a first blocking feature. The drug delivery device includes a cartridge detector comprising a second blocking feature. This feature may be a pin, for engagement with the first blocking feature of the cartridge holder when the cartridge acts on the cartridge detector. The cartridge holder may further include a fastening mechanism configured to fasten the cartridge holder to the drug delivery device only when the second blocking feature engages the first blocking feature.

Abstract: A data collection device for attachment to an injection device, such as an injector pen, includes a sensor arrangement to detect movement of a movable component of the injection device relative to the data collection device during delivery of a medicament by the injection device, and a processor arrangement configured to, based on said detected movement, determine a medicament dosage administered by the injection device. The processor arrangement may monitor the time that has elapsed since the medicament dosage was administered, and control a display to show the mediacament dosage and elapsed time to provide a memory aid to the user. In an example embodiment, the sensor arrangement includes an optical encoder and the movable component includes a plurality of light barrier formations. The movable component may be a number sleeve that provides a visual indication of a dose programmed into the injection device.

Abstract: An aerosol dispenser (1) comprising a pressurised aerosol can (2) and a closure (3) comprising an aerosol valve (4) held within a retention chassis (5), said retention chassis (5) being associated with a flexible sealing collar (6) designed to radially surround the retention chassis (5) and to seal against the edge of an opening (7) in the aerosol can (2), wherein the retention chassis (5) is axially moveable relative to the sealing collar (6) and wherein the sealing collar (6) is of outer 7A diameter greater than the inner diameter of the opening (7) in the aerosol can (2) and is sufficiently flexible to flex through the opening (7) in the aerosol can (2) when the retention chassis (5) is in a first axial position relative to the sealing collar (6) and wherein the sealing collar (6) is firmly held 2 against the edge (7) of the opening (8) in the aerosol can (2) when the retention chassis (5) is in a second axial position relative to the sealing collar (6).

Abstract: A drive mechanism of an injection device for setting and dispensing of a dose of a medicament includes a body accommodating a cartridge filled with a medicament, an insert axially displaceable inside the body between a proximal operating position and a distal reset position, a piston rod to operably engage with a piston of the cartridge, a drive sleeve rotationally coupled with the piston rod and is rotationally lockable to the body for setting of a dose and rotationally releasable from the body for dispensing of a dose, respectively. The drive sleeve is axially displaceable relative to the body from a proximal operating position into a distal reset position through an axial connection of the insert and the drive sleeve, where the drive sleeve is rotationally released from the body when in the distal reset position.

Abstract: Methods, systems, and storage media for telemetry adaptation are disclosed herein. In an embodiment, a networking device may include a data collector agent module to receive measurement data from measurement sources according to an initial telemetry policy and to provide the measurement data to the one or more servers of the monitoring system. The networking device may include an anomaly detection module to receive measurement data from the data collector agent module, to detect an anomaly in the measurement data, and to provide an indication of the anomaly to the data collector agent module for the data collector agent module to provide a first modified telemetry policy for the measurement sources.

Abstract: Apparatuses and methods associated with management of computing infrastructure resources and workloads are disclosed herein. In embodiments, an apparatus may comprise a resource-workload manager having: a placement solution generator to generate a plurality of potential resource placement solutions for allocation of various resources of the computing infrastructure to various workloads; one or more utility function calculators to calculate one or more values for one or more provider-centric attributes, and one or more values for one or more customer-centric attributes, for the plurality of potential solutions; an analyzer to analyze the attributes and select one of the potential resource placement solutions; and a resource allocator to allocate the resources, based at least in part on the selected resource placement solution. Other embodiments may be described and/or claimed.

Abstract: Techniques for dynamically adapting cloud applications are described. A current value of a Key Performance Indicator (KPI) of an executing cloud service instance of a cloud application is detected. A determination is made as to whether the current value of the KPI is unacceptable (e.g., either it is outside of an acceptable range or is within an adaptation region). If the current value of the KPI is unacceptable, a first application programming interface (API) is invoked to request a cloud service instance monitor to adapt the cloud service instance to operate within an acceptable KPI range. If the cloud service instance monitor was unsuccessful, the unacceptable KPI is escalated to the cloud service monitor for the type of the cloud service instance. If the cloud service monitor is unsuccessful, the unacceptable KPI is escalated to the application monitor.