Patents by Inventor Joseph E. Lucas

Joseph E. Lucas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11008619
    Abstract: Disclosed herein are biomarkers of platelet function and methods for assessing platelet function in response to antiplatelet therapy and for determining a prognosis, diagnosis, or risk identification in a patient by detecting at least one biomarker of platelet function in the patient as well as determining amounts thereof. The biomarkers may be used to identify a patient as a candidate for treatment with an antiplatelet agent and to monitor and adjust antiplatelet therapy in a patient.
    Type: Grant
    Filed: May 16, 2019
    Date of Patent: May 18, 2021
    Assignee: Duke University
    Inventors: Geoffrey S. Ginsburg, Joseph E. Lucas, Thomas L. Ortel, Richard C. Becker, Deepak Voora, Jen-Tsan Chi
  • Patent number: 10689701
    Abstract: Disclosed herein are biomarkers useful for identifying and/or classifying bacterial infections in a subject.
    Type: Grant
    Filed: March 15, 2014
    Date of Patent: June 23, 2020
    Assignee: Duke University
    Inventors: Ephraim Tsalik, Vance Fowler, Christopher W. Woods, Joseph E. Lucas, Geoffrey S. Ginsburg, Sun Hee Ahn
  • Publication number: 20200063203
    Abstract: Disclosed herein are biomarkers of platelet function and methods for assessing platelet function in response to antiplatelet therapy and for determining a prognosis, diagnosis, or risk identification in a patient by detecting at least one biomarker of platelet function in the patient as well as determining amounts thereof. The biomarkers may be used to identify a patient as a candidate for treatment with an antiplatelet agent and to monitor and adjust antiplatelet therapy in a patient.
    Type: Application
    Filed: May 16, 2019
    Publication date: February 27, 2020
    Inventors: Geoffrey S. Ginsburg, Joseph E. Lucas, Thomas L. Ortel, Richard C. Becker, Deepak Voora, Jen-Tsan Chi
  • Patent number: 10329618
    Abstract: Disclosed herein are biomarkers of platelet function and methods for assessing platelet function in response to anti-platelet therapy and for determining a prognosis, diagnosis, or risk identification in a patient by detecting at least one biomarker of platelet function in the patient as well as determining amounts thereof. The biomarkers may be used to identify a patient as a candidate for treatment with an antiplatelet agent and to monitor and adjust antiplatelet therapy in a patient.
    Type: Grant
    Filed: September 6, 2013
    Date of Patent: June 25, 2019
    Assignee: Duke University
    Inventors: Geoffrey S. Ginsburg, Joseph E. Lucas, Thomas L. Ortel, Richard C. Becker, Deepak Voora, Jen-Tsan Chi
  • Patent number: 9850539
    Abstract: Disclosed herein are biomarkers useful for identifying and/or classifying bacterial infections in a subject.
    Type: Grant
    Filed: October 12, 2015
    Date of Patent: December 26, 2017
    Assignee: Duke University
    Inventors: Ephraim Tsalik, Vance Fowler, Christopher W. Woods, Joseph E. Lucas, Geoffrey S. Ginsburg, Sun Hee Ahn
  • Publication number: 20160097099
    Abstract: Disclosed herein are biomarkers useful for identifying and/or classifying bacterial infections in a subject.
    Type: Application
    Filed: October 12, 2015
    Publication date: April 7, 2016
    Inventors: Ephraim Tsalik, Vance Fowler, Christopher W. Woods, Joseph E. Lucas, Geoffrey S. Ginsburg, Sun Hee Ahn
  • Publication number: 20150322514
    Abstract: Disclosed herein are biomarkers of platelet function and methods for assessing platelet function in response to anti-platelet therapy and for determining a prognosis, diagnosis, or risk identification in a patient by detecting at least one biomarker of platelet function in the patient as well as determining amounts thereof. The biomarkers may be used to identify a patient as a candidate for treatment with an antiplatelet agent and to monitor and adjust antiplatelet therapy in a patient.
    Type: Application
    Filed: September 6, 2013
    Publication date: November 12, 2015
    Inventors: Geoffrey S. Ginsburg, Joseph E. Lucas, Thomas L. Ortel, Richard C. Becker, Deepak Voora, Jen-Tsan Chi
  • Publication number: 20140323391
    Abstract: Disclosed herein are biomarkers useful for identifying and/or classifying bacterial infections in a subject.
    Type: Application
    Filed: March 15, 2014
    Publication date: October 30, 2014
    Applicant: Duke University
    Inventors: Ephraim Tsalik, Vance Fowler, Christopher W. Woods, Joseph E. Lucas, Geoffrey S. Ginsburg, Sun Hee Ahn
  • Patent number: 4329088
    Abstract: Method and apparatus for elevating a prefabricated, offshore, well-drilling or other platform on a prefabricated upright support in deep water. The platform is elevated by jacking units on a platform having legs suspended from a superstructure on the support. The upright support is stabilized against wind and wave action by four guy lines anchored at one end to the sea bottom and connected at its opposite end to the drum of winches mounted on two of the caissons. There are two drums in each of the two caissons. Each drum is connected to one guy line and is separately driven by a remotely controlled, reversible hydraulic motor. The motors are operated to maintain the support vertical and the fottings equally loaded; otherwise, uneven penetration of the footings into the sea bed would result. The guy lines are always tensioned against marine and wind forces.The platform is buoyant and has four open caisson wells arranged in the same geometric pattern as the caissons of the support.
    Type: Grant
    Filed: July 31, 1979
    Date of Patent: May 11, 1982
    Assignee: Marine Engineering Company, C.A.
    Inventor: Joseph E. Lucas
  • Patent number: 4277051
    Abstract: Method and apparatus for elevating a prefabricated, off-shore, well-drilling or other platform. The platform is elevated by jacking units on the platform having legs suspended from a superstructure on the support. At least one pair of preassembled jacking units is mounted upon the platform at each caisson well. A superstructure is premounted on the upper end of each caisson. A set of self-energizing "fail safe" slips is mounted in the superstructure near each of its ends. Each jacking unit includes a tubular jacking leg. Means are provided for positioning each jacking leg so as to positively lock its upper end in the slips in the superstructure after berthing. Each jacking unit also includes a jacking mechanism comprising two slip holders, each containing a set of self-energizing, "fail safe" slips surrounding the jacking leg. Lifting rods associated with slip holder housings are pivotally connected at their lower end to the platform.
    Type: Grant
    Filed: April 24, 1978
    Date of Patent: July 7, 1981
    Assignee: Marine Engineering Company, C. A.
    Inventor: Joseph E. Lucas
  • Patent number: 4041711
    Abstract: Method and apparatus for elevating an off-shore well drilling or other platform on a support structure in a minimum of time with maximum safety. The platforms are elevated on one or more caissons, utilizing one or more jacking units.One type of support structure comprises three caissons arranged as a tripod. The platform to be mounted thereon has three open caisson wells and is floated into position, with one caisson received in each well. A caisson locking gate is closed to hold the platform in place. A pre-set-up jacking unit is located near or straddles each caisson well. Each jacking unit includes a jacking head, one or more jacking legs pivotally connected at their upper end to the jacking head, and a jacking mechanism surrounding each jacking leg and connected by a gimbal joint at its lower end to the platform. A stabilizing frame for each jacking unit is mounted on the platform.
    Type: Grant
    Filed: January 23, 1976
    Date of Patent: August 16, 1977
    Assignee: Marine Engineering Co., C.A.
    Inventor: Joseph E. Lucas