Abstract: According to the disclosure, a target analyte detection cartridge includes a sample chamber into which sample is inserted, a metering chamber connected to the sample chamber to meter a predetermined amount of sample, a mixing chamber connected to the metering chamber to receive a magnet bead, and a waste chamber connected to the metering chamber. The metering chamber has one side connected to each of the sample chamber and the mixing chamber and another side connected to the waste chamber. A first pneumatic flow path to which pneumatic pressure is provided is connected to a waste flow path that joins the other side of the metering chamber to connect the metering chamber and the waster chamber.

Abstract: According to the disclosure, a target analyte detection cartridge includes a sample chamber into which sample is inserted, a metering chamber connected to the sample chamber to meter a predetermined amount of sample, a mixing chamber connected to the metering chamber to receive a magnet bead, and a waste chamber connected to the metering chamber. The metering chamber has one side connected to each of the sample chamber and the mixing chamber and another side connected to the waste chamber. A first pneumatic flow path to which pneumatic pressure is provided is connected to a waste flow path that joins the other side of the metering chamber to connect the metering chamber and the waster chamber.

Abstract: An actuator assembly includes an actuator drive source and a gust lock. The actuator drive source is operable to supply an actuator drive torque to drive a component. The gust lock is movable between a locked position, in which rotation of the drive source is prevented, and an unlocked position, in which rotation of the drive source is not prevented. The gust lock includes a lock shaft, a lock rotor, a lock motor, and a linear actuator. The lock shaft is rotatable with the drive source when the gust lock is in the unlocked position. The lock rotor is rotatable with the lock shaft. The lock motor is configured to supply a lock drive torque. The linear actuator is coupled to receive the lock drive torque and is configured, upon receipt of the lock drive torque, to move between an engaged position and a disengaged position.

Abstract: In some implementations, the disclosed systems and methods can be blocked by an obstacle or object, such as wall(s), door(s), or other objects such that a user cannot view the area in a real-world environment. In some implementations, the disclosed systems and methods can interface with smart lights (and/or other smart devices controlling ambient lighting) to know where lights are and how much light they are putting out. In some implementations, the disclosed systems and methods can be animated via user tracking. Some user systems may lack video tracking and/or comprise inconsistent video tracking. In some implementations, the disclosed systems and methods can display content for a screen in a pass-through visualization.

Abstract: A computing device selects new test configurations for testing software. (A) First test configurations are generated using a random seed value. (B) Software under test is executed with the first test configurations to generate a test result for each. (C) Second test configurations are generated from the first test configurations and the test results generated for each. (D) The software under test is executed with the second test configurations to generate the test result for each. (E) When a restart is triggered based on a distance metric value computed between the second test configurations, a next random seed value is selected as the random seed value and (A) through (E) are repeated. (F) When the restart is not triggered, (C) through (F) are repeated until a stop criterion is satisfied. (G) When the stop criterion is satisfied, the test result is output for each test configuration.

Abstract: Provided herein are specific doses of, and dosing regimens for, using a HIF prolyl hydroxylase inhibitor in treating or preventing anemia, such as anemia secondary to or associated with chronic kidney disease, anemia associated with or resulting from chemotherapy, or anemia associated with AIDS.

Abstract: Aspects of the invention relate to a cyber security system that may enable an end user to communicate with a cyber security appliance to identify cyber threats across the client system. The system can include one or more host devices each having a user interface and an endpoint agent for facilitating bi-directional communication between the user and a cyber security appliance. The endpoint agent may include a communication facilitation module including a user interaction module configured to communicate with the user interface and a helper module configured to communicate with the cyber security appliance. The endpoint agent is configured to enable the bi-directional communication between the user interface and the cyber security appliance on receiving a query associated with identified unusual behavior.

Abstract: A computing device selects new test configurations for testing software. (A) First test configurations are generated using a random seed value. (B) Software under test is executed with the first test configurations to generate a test result for each. (C) Second test configurations are generated from the first test configurations and the test results generated for each. (D) The software under test is executed with the second test configurations to generate the test result for each. (E) When a restart is triggered based on a distance metric value computed between the second test configurations, a next random seed value is selected as the random seed value and (A) through (E) are repeated. (F) When the restart is not triggered, (C) through (F) are repeated until a stop criterion is satisfied. (G) When the stop criterion is satisfied, the test result is output for each test configuration.

Abstract: Tuned hyperparameter values are determined for training a machine learning model. When a selected hyperparameter configuration does not satisfy a linear constraint, if a projection of the selected hyperparameter configuration is included in a first cache that stores previously computed projections is determined. When the projection is included in the first cache, the projection is extracted from the first cache using the selected hyperparameter configuration, and the selected hyperparameter configuration is replaced with the extracted projection in the plurality of hyperparameter configurations. When the projection is not included in the first cache, a projection computation for the selected hyperparameter configuration is assigned to a session. A computed projection is received from the session for the selected hyperparameter configuration.

Abstract: Tuned hyperparameter values are determined for training a machine learning model. When a selected hyperparameter configuration does not satisfy a linear constraint, if a projection of the selected hyperparameter configuration is included in a first cache that stores previously computed projections is determined. When the projection is included in the first cache, the projection is extracted from the first cache using the selected hyperparameter configuration, and the selected hyperparameter configuration is replaced with the extracted projection in the plurality of hyperparameter configurations. When the projection is not included in the first cache, a projection computation for the selected hyperparameter configuration is assigned to a session. A computed projection is received from the session for the selected hyperparameter configuration.

Abstract: Manufacturing processes can be optimized using machine learning models. For example, a system can execute an optimization model to identify a recommended set of values for configurable settings of a manufacturing process associated with an object. The optimization model can determine the recommended set of values by implementing an iterative process using an objective function. Each iteration of the iterative process can include selecting a current set of candidate values for the configurable settings from within a current region of a search space defined by the optimization model; providing the current set of candidate values as input to a trained machine learning model that can predict a value for a target characteristic of the object or the manufacturing process based on the current set of candidate values; and identifying a next region of the search space to use in a next iteration of the iterative process based on the value.

Abstract: A computing device selects decision variable values. A lower boundary value and an upper boundary value is defined for a decision variable. (A) A plurality of decision variable configurations is determined using a search method. The value for the decision variable is between the lower boundary value and the upper boundary value. (B) A decision variable configuration is selected. (C) A model of the model type is trained using the decision variable configuration. (D) The model is scored to compute an objective function value. (E) The computed objective function value and the selected decision variable configuration are stored. (F) (B) through (E) is repeated for a plurality of decision variable configurations. (G) The lower boundary value and the upper boundary value are updated using the objective function value and the decision variable configuration stored. Repeat (A)-(F) with the lower boundary value and the upper boundary value updated in (G).

Abstract: Described herein are technologies for concentrating rare-earth elements from a heavy fraction of grit in gangue produced in kaolin mining. In some examples, grit is separated as a non-clay fraction of gangue produced in a kaolin mining operation. The grit is separated into a heavy mineral grit sub-fraction and a light mineral grit sub-fraction. Rare-earth elements, particularly heavy rare-earth elements, are thereafter extracted from the heavy mineral grit sub-fraction using various extraction technologies.

Abstract: Systems and methods of providing composite search results are disclosed. A search query may be received by a general purpose search engine of a first website from a user. At least one general purpose search result may be determined based on the search query using the general purpose search engine. The at least one general purpose search result may be based on a search of multiple websites. Item listing information of an item listed for sale on a second website may be determined based on the search query. The at least one general purpose search result and the item listing information may be caused to be displayed concurrently on the first website to the user. The user may be enabled to interact with the second website regarding the item by interacting with the item listing information displayed on the first website.

Abstract: Described herein are technologies for concentrating rare-earth elements from a heavy fraction of grit in gangue produced in kaolin mining. In some examples, grit is separated as a non-clay fraction of gangue produced in a kaolin mining operation. The grit is separated into a heavy mineral grit sub-fraction and a light mineral grit sub-fraction. Rare-earth elements, particularly heavy rare-earth elements, are thereafter extracted from the heavy mineral grit sub-fraction using various extraction technologies.

Abstract: Described herein are technologies for concentrating rare-earth elements from a heavy fraction of grit in gangue produced in kaolin mining. In some examples, grit is separated as a non-clay fraction of gangue produced in a kaolin mining operation. The grit is separated into a heavy mineral grit sub-fraction and a light mineral grit sub-fraction. Rare-earth elements, particularly heavy rare-earth elements, are thereafter extracted from the heavy mineral grit sub-fraction using various extraction technologies.

Abstract: A computing device automatically selects hyperparameter values based on objective criteria to train a predictive model. Each session of a plurality of sessions executes training and scoring of a model type using an input dataset in parallel with other sessions of the plurality of sessions. Unique hyperparameter configurations are determined using a search method and assigned to each session. For each session of the plurality of sessions, training of a model of the model type is requested using a training dataset and the assigned hyperparameter configuration, scoring of the trained model using a validation dataset and the assigned hyperparameter configuration is requested to compute an objective function value, and the received objective function value and the assigned hyperparameter configuration are stored. A best hyperparameter configuration is identified based on an extreme value of the stored objective function values.

Abstract: A computing device automatically selects hyperparameter values based on objective criteria to train a predictive model. Each session of a plurality of sessions executes training and scoring of a model type using an input dataset in parallel with other sessions of the plurality of sessions. Unique hyperparameter configurations are determined using a search method and assigned to each session. For each session of the plurality of sessions, training of a model of the model type is requested using a training dataset and the assigned hyperparameter configuration, scoring of the trained model using a validation dataset and the assigned hyperparameter configuration is requested to compute an objective function value, and the received objective function value and the assigned hyperparameter configuration are stored. A best hyperparameter configuration is identified based on an extreme value of the stored objective function values.

Abstract: A magnetic coupling device for communicating continuous rotational or linear motion through a magnetic coupling of magnetic forces communicated from magnets operatively positioned on an oscillation assembly and a rotation assembly in positions sufficiently proximate to form the magnetic coupling. Employed to communicate an output force in a rotational direction from an input linear force communicated from a powered oscillation assembly, the magnetic force of the magnet communicating the force compresses the volume of ellipsoidal-like magnetic fields of the coupling alternately in unlike polar domains, to induce a smooth, blended polar continuity and communicate a continuous 360 degree rotational force to a rotation assembly operatively engaged with the magnetic coupling. The input force may be reversed to induce a continuous linear motion of a reciprocating assembly.

Abstract: Systems and methods of providing composite search results are disclosed. A search query may be received by a general purpose search engine of a first website from a user. At least one general purpose search result may be determined based on the search query using the general purpose search engine. The at least one general purpose search result may be based on a search of multiple websites. Item listing information of an item listed for sale on a second website may be determined based on the search query. The at least one general purpose search result and the item listing information may be caused to be displayed concurrently on the first website to the user. The user may be enabled to interact with the second website regarding the item by interacting with the item listing information displayed on the first website.