Patents by Inventor Joseph Gruber

Joseph Gruber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11428137
    Abstract: In a method for operating a urea dosing system in an exhaust aftertreatment system (EATS) of an engine, an ambient temperature is measured in an environment in which the EATS is disposed, one or more temperatures associated with the EATS to which there is a relationship to a temperature of area in the urea dosing system are monitored. After turning off the engine, whether urea in the urea dosing system is subject to freezing is determined based on the measured ambient temperature and the one or more monitored temperatures. A reversion operation is performed after turning off the engine with a delay until one or more events occur, the one or more events including determining that urea in the urea dosing system is subject to freezing. An engine system is also provided.
    Type: Grant
    Filed: January 2, 2019
    Date of Patent: August 30, 2022
    Assignee: VOLVO TRUCK CORPORATION
    Inventors: Joseph Gruber, Jeffrey Zsoldos, Timothy Jacobson, Michael Pecsko
  • Publication number: 20220010711
    Abstract: In a method for operating a urea dosing system in an exhaust aftertreatment system (EATS) of an engine, an ambient temperature is measured in an environment in which the EATS is disposed, one or more temperatures associated with the EATS to which there is a relationship to a temperature of area in the urea dosing system are monitored. After turning off the engine, whether urea in the urea dosing system is subject to freezing is determined based on the measured ambient temperature and the one or more monitored temperatures. A reversion operation is performed after turning off the engine with a delay until one or more events occur, the one or more events including determining that urea in the urea dosing system is subject to freezing. An engine system is also provided.
    Type: Application
    Filed: January 2, 2019
    Publication date: January 13, 2022
    Applicant: VOLVO TRUCK CORPORATION
    Inventors: Joseph GRUBER, Jeffrey ZSOLDOS, Timothy JACOBSON, Michael PECSKO
  • Patent number: 10794898
    Abstract: Methods for identifying a compound that alters fluorescence resonance energy transfer (FRET) of a protein. The methods include use of a genetically engineered cell that includes a target protein. The target protein includes one or more heterologous domains. In one embodiment, a target protein includes two heterologous domains, and in another embodiment, the target protein includes a heterologous domain and the cell further includes a second protein that includes a heterologous domain. A heterologous domain may include a chromophore or an amino acid to which a fluorescent dye attaches. The fluorescence lifetime of one or more chromophore, one or more fluorescent dye, or the combination thereof, is measured after contacting the cell with a compound A difference between the fluorescence lifetime in the presence of the test compound and the fluorescence lifetime in the absence of the test compound indicates that the test compound alters the FRET of the target protein.
    Type: Grant
    Filed: January 16, 2015
    Date of Patent: October 6, 2020
    Assignees: Regents of the University of Minnesota, Loyola University Chicago
    Inventors: David D. Thomas, Simon Joseph Gruber, Razvan L. Cornea, Gregory David Gillispie, Kurt C. Peterson, Seth Louis Robia
  • Publication number: 20150204847
    Abstract: Methods for identifying a compound that alters fluorescence resonance energy transfer (FRET) of a protein. The methods include use of a genetically engineered cell that includes a target protein. The target protein includes one or more heterologous domains. In one embodiment, a target protein includes two heterologous domains, and in another embodiment, the target protein includes a heterologous domain and the cell further includes a second protein that includes a heterologous domain. A heterologous domain may include a chromophore or an amino acid to which a fluorescent dye attaches. The fluorescence lifetime of one or more chromophore, one or more fluorescent dye, or the combination thereof, is measured after contacting the cell with a compound A difference between the fluorescence lifetime in the presence of the test compound and the fluorescence lifetime in the absence of the test compound indicates that the test compound alters the FRET of the target protein.
    Type: Application
    Filed: January 16, 2015
    Publication date: July 23, 2015
    Inventors: David D. Thomas, Simon Joseph Gruber, Razvan L. Cornea, Gregory David Gillispie, Kurt C. Peterson, Seth Louis Robia
  • Patent number: 8591577
    Abstract: A capsulotomy device for use in an eye having a capsular bag, comprising a conductive, primary coil capable of generating magnetic field lines and a conductive, secondary coil configured to permit insertion through an incision having a diameter of 3 mm or less, and placement on the capsular bag. When the magnetic field lines are projected through the secondary coil, a current is generated within the secondary coil.
    Type: Grant
    Filed: December 16, 2010
    Date of Patent: November 26, 2013
    Assignee: Bausch & Lomb Incorporated
    Inventors: Ala Moradian, Joseph Gruber
  • Publication number: 20120158130
    Abstract: A capsulotomy device for use in an eye having a capsular bag, comprising a conductive, primary coil capable of generating magnetic field lines and a conductive, secondary coil configured to permit insertion through an incision having a diameter of 3 mm or less, and placement on the capsular bag. When the magnetic field lines are projected through the secondary coil, a current is generated within the secondary coil.
    Type: Application
    Filed: December 16, 2010
    Publication date: June 21, 2012
    Inventors: Ala Moradian, Joseph Gruber
  • Patent number: 8177502
    Abstract: An airfoil assembly is described comprising an airfoil, a band coupled to the airfoil for providing at least a portion of support for the airfoil in the airfoil assembly and a slot capable reducing stress in the airfoil wherein the slot is located in the band near a portion of the airfoil. A compression system is described comprising a stator assembly comprising a plurality of arcuate vane sectors arranged circumferentially around a longitudinal axis, each vane sector comprising an airfoil, an arcuate inner band and an arcuate outer band coupled to the airfoil, and a slot capable of reducing stress in the airfoil, the slot being located in the vane sector near a portion of the airfoil.
    Type: Grant
    Filed: November 25, 2008
    Date of Patent: May 15, 2012
    Assignee: General Electric Company
    Inventors: Mitchell Jay Headley, Stephen Joseph Gruber
  • Publication number: 20100126018
    Abstract: A method of manufacturing an airfoil assembly is described, the method comprising the steps of supplying an airfoil and a band, creating a support aperture in the band capable of receiving a portion of the airfoil, creating a slot in the band for reducing stress in the airfoil, and bonding the airfoil with the band.
    Type: Application
    Filed: November 25, 2008
    Publication date: May 27, 2010
    Inventors: Mitchell Jay Headley, Stephen Joseph Gruber
  • Publication number: 20100129210
    Abstract: An airfoil assembly is described comprising an airfoil, a band coupled to the airfoil for providing at least a portion of support for the airfoil in the airfoil assembly and a slot capable reducing stress in the airfoil wherein the slot is located in the band near a portion of the airfoil. A compression system is described comprising a stator assembly comprising a plurality of arcuate vane sectors arranged circumferentially around a longitudinal axis, each vane sector comprising an airfoil, an arcuate inner band and an arcuate outer band coupled to the airfoil, and a slot capable of reducing stress in the airfoil, the slot being located in the vane sector near a portion of the airfoil.
    Type: Application
    Filed: November 25, 2008
    Publication date: May 27, 2010
    Inventors: Mitchell Jay Headley, Stephen Joseph Gruber