Patents by Inventor Joseph J. Brown
Joseph J. Brown has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240148826Abstract: Nucleic acid molecules that include a nucleotide sequence encoding a chimeric antigen receptor (CAR) and a nucleotide sequence encoding a protease sensitive scFv, wherein the chimeric antigen receptor comprises: an scFv targeting a tumor antigen, a spacer, a transmembrane domain, a co-stimulatory domain, and a CD3 ? signaling domain; and the protease-sensitive scFv and the scFv target the same tumor antigen are described.Type: ApplicationFiled: June 5, 2023Publication date: May 9, 2024Inventors: Xiuli Wang, Stephen J. Forman, Lawrence Stern, Christine E. Brown, Joseph Cohen
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Patent number: 11972680Abstract: Table top sanitizer dispenser bottle bases are disclosed herein. An exemplary table top sanitizer dispenser bottle base includes a movable upper housing, the upper moveable housing has a floor with an aperture located therein and a peripheral wall. The top sanitizer dispenser bottle includes a lower stationary housing. The upper movable housing is connected to the lower stationary housing and is configured to move linearly upward and downward with respect to lower stationary. One or more biasing members bias the upper movable housing upward. A switch is included and the upper movable housing has an engagement member or surface for actuating the switch upon downward movement of the upper movable housing. At least one of a visual indicator and an audible indicator are also included. Control circuitry is provided for activating the one or more of a visual indicator and audible indicator when the engagement member actuates the switch.Type: GrantFiled: June 10, 2021Date of Patent: April 30, 2024Assignee: GOJO Industries, Inc.Inventors: Aaron D. Marshall, Mark T. Smith, Paul J. Brown, Aaron R. Reynolds, Joseph S. Kanfer, Shelby Jay Buell, Eugene W. Ray
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Patent number: 11565936Abstract: The present invention relates to the unexpected discovery of novel methods of preparing nanodevices and/or microdevices with predetermined patterns. In one aspect, the methods of the invention allow for engineering structures and films with continuous thickness equal to or less than 50 nm.Type: GrantFiled: May 25, 2017Date of Patent: January 31, 2023Assignees: The Regents of the University of Colorado, DRS Network & Imaging Systems, LLCInventors: Steven M. George, Victor M. Bright, Joseph J. Brown, Jonas Gertsch, Nathan Thomas Eigenfeld, George Skidmore
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Patent number: 11413847Abstract: A system that receives nanomaterials, forms nanofibrous materials therefrom, and collects these nanofibrous materials for subsequent applications. The system is coupled to a chamber that generates nanomaterials, typically carbon nanotubes produced from chemical vapor deposition, and includes a mechanism for spinning the nanotubes into yarns or tows. Alternatively, the system includes a mechanism for forming non-woven sheets from the nanotubes. The system also includes components for collecting the formed nanofibrous materials. Methods for forming and collecting the nanofibrous materials are also provided.Type: GrantFiled: March 16, 2016Date of Patent: August 16, 2022Assignee: Nanocomp Technologies, Inc.Inventors: David S. Lashmore, Joseph J. Brown, Jared K. Chaffee, Bruce Resnicoff, Peter Antoinette
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Patent number: 11067511Abstract: Methods and devices for real-time detection of fouling chemistry are described herein. In one aspect, a method of detecting and characterizing fouling of a membrane used for separation in a fluid-based system can include illuminating the membrane with one or more light sources, collecting Raman spectroscopy data from the membrane, and based on the Raman data, determining at least one selected from the group consisting of: presence or absence of membrane fouling, severity of membrane fouling, and composition of the membrane fouling, where the Raman spectroscopy is selected from the group consisting of Coherent Anti-Stokes Raman Scattering (CARS), Stimulated Raman Scattering (SRS), and spontaneous Raman Scattering.Type: GrantFiled: September 19, 2019Date of Patent: July 20, 2021Assignee: The Regents of the University of Colorado, a body corporateInventors: Joseph J. Brown, Omkar D. Supekar, Victor M. Bright, Juliet T. Gopinath, Alan R. Greenberg
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Patent number: 10807864Abstract: The invention includes a method of promoting interfacial mechanical bonding of two or more components through the use of suspended and/or freestanding structures fabricated using an atom-scale assembly process on at least a portion of the surfaces of such components.Type: GrantFiled: January 29, 2018Date of Patent: October 20, 2020Assignee: The Regents of the University of Colorado, a body corporateInventors: Joseph J. Brown, Victor M. Bright
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Publication number: 20200316645Abstract: The present invention relates to the unexpected discovery of novel methods of preparing nanodevices and/or microdevices with predetermined patterns. In one aspect, the methods of the invention allow for engineering structures and films with continuous thickness equal to or less than 50 nm.Type: ApplicationFiled: May 25, 2017Publication date: October 8, 2020Applicants: The Regents of the University of Colorado, a Body Corporate, DRS Network & Imaging Systems, LLCInventors: Steven M. GEORGE, Victor M. BRIGHT, Joseph J. BROWN, Jonas GERTSCH, Nathan Thomas EIGENFELD, George SKIDMORE
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Publication number: 20200088647Abstract: Methods and devices for real-time detection of fouling chemistry are described herein. In one aspect, a method of detecting and characterizing fouling of a membrane used for separation in a fluid-based system can include illuminating the membrane with one or more light sources, collecting Raman spectroscopy data from the membrane, and based on the Raman data, determining at least one selected from the group consisting of: presence or absence of membrane fouling, severity of membrane fouling, and composition of the membrane fouling, where the Raman spectroscopy is selected from the group consisting of Coherent Anti-Stokes Raman Scattering (CARS), Stimulated Raman Scattering (SRS), and spontaneous Raman Scattering.Type: ApplicationFiled: September 19, 2019Publication date: March 19, 2020Inventors: JOSEPH J. BROWN, OMKAR D. SUPEKAR, VICTOR M. BRIGHT, JULIET T. GOPINATH, ALAN R. GREENBERG
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Patent number: 10171919Abstract: In one aspect, the present invention provides nano-scale heaters, such as nano-scale thermoacoustic loudspeakers comprising suspended metal nanobridges prepared using atomic layer deposition (ALD). The loudspeakers of the invention are capable of producing audible sound when stimulated with an electrical current or other energetic stimulus. In another aspect, the present invention provides methods of preparing and using such nanodevices.Type: GrantFiled: May 16, 2017Date of Patent: January 1, 2019Assignee: The Regents of the University of Colorado, a body corporateInventors: Victor M. Bright, Joseph J. Brown
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Publication number: 20180297319Abstract: A system that receives nanomaterials, forms nanofibrous materials therefrom, and collects these nanofibrous materials for subsequent applications. The system include a housing coupled to a synthesis chamber within which nanotubes are produced. A spindle may extend from within the housing, across the inlet, and into the chamber for collecting nanotubes and twisting them into a yarn. A body portion may be positioned at an intake end of the spindle. The body portion may include a pathway for imparting a twisting force onto the flow of nanotubes and guide them into the spindle for collection and twisting into the nanofibrous yarn. Methods and apparatuses for forming nanofibrous are also disclosed.Type: ApplicationFiled: June 20, 2018Publication date: October 18, 2018Inventors: David S. Lashmore, Joseph J. Brown, Jared K. Chaffee, Bruce Resnicoff, Peter Antoinette
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Publication number: 20180215613Abstract: The invention includes a method of promoting interfacial mechanical bonding of two or more components through the use of suspended and/or freestanding structures fabricated using an atom-scale assembly process on at least a portion of the surfaces of such components.Type: ApplicationFiled: January 29, 2018Publication date: August 2, 2018Inventors: JOSEPH J. BROWN, VICTOR M. BRIGHT
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Patent number: 10029442Abstract: A system that receives nanomaterials, forms nanofibrous materials therefrom, and collects these nanofibrous materials for subsequent applications. The system include a housing coupled to a synthesis chamber within which nanotubes are produced. A spindle may extend from within the housing, across the inlet, and into the chamber for collecting nanotubes and twisting them into a yarn. A body portion may be positioned at an intake end of the spindle. The body portion may include a pathway for imparting a twisting force onto the flow of nanotubes and guide them into the spindle for collection and twisting into the nanofibrous yarn. Methods and apparatuses for forming nanofibrous are also disclosed.Type: GrantFiled: February 27, 2015Date of Patent: July 24, 2018Assignee: NANOCOMP TECHNOLOGIES, INC.Inventors: David S. Lashmore, Joseph J. Brown, Jared K. Chaffee, Bruce Resnicoff, Peter Antoinette
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Patent number: 9919921Abstract: The present invention relates to novel nano- and micro-electromechanical devices and novel methods of preparing them. In one aspect, the invention includes methods of preparing a nanodevice. In certain embodiments, the methods comprise coating a polymer layer with a first at least one thin solid material layer using atomic layer deposition (ALD), thus forming an ALD-generated layer. In other embodiments, the methods comprise patterning the first at least one thin solid material layer to form a nanodevice. In yet other embodiments, the methods comprise releasing the nanodevice from the polymer layer.Type: GrantFiled: January 26, 2015Date of Patent: March 20, 2018Assignees: The Regents of the University of Colorado, a body corporate, DRS Network & Imaging Systems, LLCInventors: Victor M. Bright, Steven George, Joseph J. Brown, Nathan T. Eigenfeld, Jason M. Gray, George Dee Skidmore
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Publication number: 20170332179Abstract: In one aspect, the present invention provides nano-scale heaters, such as nano-scale thermoacoustic loudspeakers comprising suspended metal nanobridges prepared using atomic layer deposition (ALD). The loudspeakers of the invention are capable of producing audible sound when stimulated with an electrical current or other energetic stimulus. In another aspect, the present invention provides methods of preparing and using such nanodevices.Type: ApplicationFiled: May 16, 2017Publication date: November 16, 2017Inventors: VICTOR M. BRIGHT, JOSEPH J. BROWN
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Publication number: 20160304341Abstract: The present invention relates to novel nano- and micro-electromechanical devices and novel methods of preparing them. In one aspect, the invention includes methods of preparing a nanodevice. In certain embodiments, the methods comprise coating a polymer layer with a first at least one thin solid material layer using atomic layer deposition (ALD), thus forming an ALD-generated layer. In other embodiments, the methods comprise patterning the first at least one thin solid material layer to form a nanodevice. In yet other embodiments, the methods comprise releasing the nanodevice from the polymer layer.Type: ApplicationFiled: January 26, 2015Publication date: October 20, 2016Inventors: Victor M. Bright, Steven George, Joseph J. Brown, Nathan T. Eigenfeld, Jason M. Gray, George Dee Skidmore
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Publication number: 20160250823Abstract: A system that receives nanomaterials, forms nanofibrous materials therefrom, and collects these nanofibrous materials for subsequent applications. The system is coupled to a chamber that generates nanomaterials, typically carbon nanotubes produced from chemical vapor deposition, and includes a mechanism for spinning the nanotubes into yarns or tows. Alternatively, the system includes a mechanism for forming non-woven sheets from the nanotubes. The system also includes components for collecting the formed nanofibrous materials. Methods for forming and collecting the nanofibrous materials are also provided.Type: ApplicationFiled: March 16, 2016Publication date: September 1, 2016Inventors: David S. Lashmore, Joseph J. Brown, Jared K. Chaffee, Bruce Resnicoff, Peter Antoinette
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Publication number: 20150176163Abstract: A system that receives nanomaterials, forms nanofibrous materials therefrom, and collects these nanofibrous materials for subsequent applications. The system include a housing coupled to a synthesis chamber within which nanotubes are produced. A spindle may extend from within the housing, across the inlet, and into the chamber for collecting nanotubes and twisting them into a yarn. A body portion may be positioned at an intake end of the spindle. The body portion may include a pathway for imparting a twisting force onto the flow of nanotubes and guide them into the spindle for collection and twisting into the nanofibrous yarn. Methods and apparatuses for forming nanofibrous are also disclosed.Type: ApplicationFiled: February 27, 2015Publication date: June 25, 2015Inventors: David S. Lashmore, Joseph J. Brown, Jared K. Chaffee, Bruce Resnicoff, Peter Antoinette
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Patent number: 8999285Abstract: A system that receives nanomaterials, forms nanofibrous materials therefrom, and collects these nanofibrous materials for subsequent applications. The system include a housing coupled to a synthesis chamber within which nanotubes are produced. A spindle may extend from within the housing, across the inlet, and into the chamber for collecting nanotubes and twisting them into a yarn. A body portion may be positioned at an intake end of the spindle. The body portion may include a pathway for imparting a twisting force onto the flow of nanotubes and guide them into the spindle for collection and twisting into the nanofibrous yarn. Methods and apparatuses for forming nanofibrous are also disclosed.Type: GrantFiled: July 26, 2011Date of Patent: April 7, 2015Assignee: Nanocomp Technologies, Inc.Inventors: David S. Lashmore, Joseph J. Brown, Jared K. Chaffee, Bruce Resnicoff, Peter Antoinette
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Publication number: 20110316183Abstract: A system that receives nanomaterials, forms nanofibrous materials therefrom, and collects these nanofibrous materials for subsequent applications. The system include a housing coupled to a synthesis chamber within which nanotubes are produced. A spindle may extend from within the housing, across the inlet, and into the chamber for collecting nanotubes and twisting them into a yarn. A body portion may be positioned at an intake end of the spindle. The body portion may include a pathway for imparting a twisting force onto the flow of nanotubes and guide them into the spindle for collection and twisting into the nanofibrous yarn. Methods and apparatuses for forming nanofibrous are also disclosed.Type: ApplicationFiled: July 26, 2011Publication date: December 29, 2011Applicant: Nanocomp Technologies, Inc.Inventors: David S. Lashmore, Joseph J. Brown, Jared K. Chaffee, Bruce Resnicoff, Peter Antoinette
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Publication number: 20110214850Abstract: A heat-conducting medium for placement between a heat source and heat sink to facilitate transfer of heat from the source to the sink is provided. The heat-conducting medium can include a disk having relatively high thermal conductivity and heat spreading characteristics. The heat-conducting medium also includes a first recessed surface and an opposing second recessed surface. Extending from within each recessed surface is an array of heat conducting bristles to provide a plurality of contact points to the heat source and heat sink to aid in the transfer of heat. The recessed surfaces may be defined by a rim positioned circumferentially about the disk. The presence of the rim about each recessed surface acts to minimize the amount of pressure that may be exerted by the heat sink and the heat source against the bristles. A method for manufacturing the heat-conducting medium is also provided.Type: ApplicationFiled: January 18, 2011Publication date: September 8, 2011Inventors: David S. Lashmore, Joseph J. Brown