Patents by Inventor Joseph J. Kirkland
Joseph J. Kirkland has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20090297853Abstract: A process for preparing nanoparticle coated surfaces including the steps of electrostatically coating surfaces with polyelectrolyte by exposing the surface to a solution or suspension of polyelectrolyte, removing excess non-bound polyelectrolyte, then further coating the particles with a multi-layer of charged nanoparticles by exposing the polyelectrolyte-coated surface to a fluid dispersion including the charged nanoparticles. The process steps can optionally be repeated thereby adding further layers of polyelectrolyte followed by nanoparticles as many times as desired to produce a second and subsequent layers. The polyelectrolyte has an opposite surface charge to the charged nanoparticles and a molecular weight at the ionic strength of the fluid that is effective so that the first, second, and subsequent layers independently comprise a multiplicity of nanoparticle layers that are thicker than monolayers.Type: ApplicationFiled: June 23, 2009Publication date: December 3, 2009Applicant: Advanced Materials Technology, Inc.Inventors: Joseph J. Kirkland, Timothy J. Langlois
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Publication number: 20080277346Abstract: A process for preparing nanoparticle coated surfaces including the steps of electrostatically coating surfaces with polyelectrolyte by exposing the surface to a solution or suspension of polyelectrolyte, removing excess non-bound polyelectrolyte, then further coating the particles with a multi-layer of charged nanoparticles by exposing the polyelectrolyte-coated surface to a fluid dispersion including the charged nanoparticles. The process steps can optionally be repeated thereby adding further layers of polyelectrolyte followed by nanoparticles as many times as desired to produce a second and subsequent layers. The polyelectrolyte has an opposite surface charge to the charged nanoparticles and a molecular weight at the ionic strength of the fluid that is effective so that the first, second, and subsequent layers independently comprise a multiplicity of nanoparticle layers that are thicker than monolayers.Type: ApplicationFiled: February 13, 2007Publication date: November 13, 2008Inventors: Joseph J. Kirkland, Timothy J. Langlois
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Publication number: 20070189944Abstract: The present invention relates to microparticles, particularly spherical silica microparticles, which may be useful in liquid chromatography. Specifically, the microparticles include a solid core and an outer porous shell surrounding and irreversibly joined to the core. The shell is composed of a plurality of colloidal nanoparticles, which are applied using an electrostatic multi-multilayering method. The resulting microparticles have a small particle diameter, such as about 1 ?m to 3.5 ?m, a high particle density, such as about 1.2 g/cc to 1.9 g/cc, and a high surface area, such as about 50 m2/g to 165 m2/g. These microparticles can be used to form packed beds and liquid chromatographic columns, which are more efficient and rugged than conventional liquid chromatographic columns.Type: ApplicationFiled: February 13, 2007Publication date: August 16, 2007Inventors: Joseph J. Kirkland, Timothy J. Langlois
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Patent number: 7128884Abstract: Highly purified, porous silica microspheres contain functional groups which are capable of selectively binding to reaction impurities, such as excess reactant or reaction by-products, which are contained in a reaction medium. The reaction impurities can thereby be efficiently removed from the reaction medium, providing a convenient method for product purification.Type: GrantFiled: October 28, 2003Date of Patent: October 31, 2006Assignee: Agilent Technologies, Inc.Inventors: Joseph J. Kirkland, Timothy J. Langlois, Qunjie Wang
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Patent number: 7041623Abstract: Highly purified, porous silica microspheres contain functional groups which are capable of selectively binding to reaction impurities, such as excess reactant or reaction by-products, which are contained in a reaction medium. The reaction impurities can thereby be efficiently removed from the reaction medium, providing a convenient method for product purification.Type: GrantFiled: October 23, 2002Date of Patent: May 9, 2006Assignee: Agilent Technologies, Inc.Inventors: Joseph J. Kirkland, Timothy J. Langlois, Ounjie Wang
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Publication number: 20040089606Abstract: Highly purified, porous silica microspheres contain functional groups which are capable of selectively binding to reaction impurities, such as excess reactant or reaction by-products, which are contained in a reaction medium. The reaction impurities can thereby be efficiently removed from the reaction medium, providing a convenient method for product purification.Type: ApplicationFiled: October 28, 2003Publication date: May 13, 2004Inventors: Joseph J. Kirkland, Timothy J. Longlois, Qunjie Wang
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Publication number: 20030136739Abstract: Highly purified, porous silica microspheres contain functional groups which are capable of selectively binding to reaction impurities, such as excess reactant or reaction by-products, which are contained in a reaction medium. The reaction impurities can thereby be efficiently removed from the reaction medium, providing a convenient method for product purification.Type: ApplicationFiled: October 23, 2002Publication date: July 24, 2003Inventors: Joseph J. Kirkland, Timothy J. Langlois, Qunjie Wang
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Patent number: 6482324Abstract: Highly purified, porous silica microspheres contain functional groups which are capable of selectively binding to reaction impurities, such as excess reactant or reaction by-products, which are contained in a reaction medium. The reaction impurities can thereby be efficiently removed from the reaction medium, providing a convenient method for product purification.Type: GrantFiled: December 26, 2001Date of Patent: November 19, 2002Assignee: Agilent Technologies, Inc.Inventors: Joseph J. Kirkland, Timothy J. Langlois, Ounjie Wang
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Publication number: 20020132119Abstract: Highly purified, porous silica microspheres contain functional groups which are capable of selectively binding to reaction impurities, such as excess reactant or reaction by-products, which are contained in a reaction medium. The reaction impurities can thereby be efficiently removed from the reaction medium, providing a convenient method for product purification.Type: ApplicationFiled: December 26, 2001Publication date: September 19, 2002Inventors: Joseph J. Kirkland, Timothy J. Langlois, Ounjie Wang
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Patent number: 6057468Abstract: The present invention provides propylene-bridged bidentate silane reagents for modifying the surface of liquid chromatography supports, these supports and methods of making and using the same. When bonded to the surface of a support material, the resulting modified support material provides improved properties, such as better separations and more stable support materials, especially when used in liquid chromatography. These bidentate silanes have the general structure: RSiMe(NMe.sub.2)--(CH.sub.2).sub.3 --SiMeR--NMe.sub.2. R is an n-octadecyl group or an n-tetradecyl group, and Me is a methyl group. When reacted with a silica surface, the resulting modified surface has a structure: PSiO--[RSiMe--(CH.sub.2).sub.3 --SiMeR]--OSiP. PSiO is surface-reacted silica.Type: GrantFiled: April 16, 1999Date of Patent: May 2, 2000Assignee: Hewlett-Packard CompanyInventors: Joseph J. Kirkland, John B. Adams, Jr.
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Patent number: 5948531Abstract: The present invention provides propylene-bridged bidentate silane reagents for modifying the surface of liquid chromatography supports, these supports and methods of making and using the same. When bonded to the surface of a support material, the resulting modified support material provides improved properties, such as better separations and more stable support materials, especially when used in liquid chromatography. These bidentate silanes have the general structure: RSiMe(NMe.sub.2)--(CH.sub.2).sub.3 --SiMeR--NMe.sub.2. R is an n-octadecyl group or an n-tetradecyl group, and Me is a methyl group. When reacted with a silica surface, the resulting modified surface has a structure: PSiO--?RSiMe--(CH.sub.2).sub.3 --SiMeR!--OSiP. PSiO is surface-reacted silica.Type: GrantFiled: June 20, 1997Date of Patent: September 7, 1999Assignee: Hewlett-Packard CompanyInventors: Joseph J Kirkland, John B. Adams, Jr.
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Patent number: 5869724Abstract: The present invention provides asymmetric bidentate silane reagents from modifying the surface of liquid chromatography supports, the supports and methods of making and using the same. When bonded to the surface of a support material, the resulting modified support material provides improved properties, such as better separations and more stable support materials, especially when used in liquid chromatography. These bidentate silanes have the general structure: R.sub.1 SiMe(NMe.sub.2)--(CH.sub.2).sub.n --SiMeR.sub.2 (NMe.sub.2). R.sub.1 is an alkyl group having from 1 to 30 carbon atoms, and R.sub.2 is an alkyl group having from 8 to 18 carbon atoms. R.sub.1 is a different alkyl group than R.sub.2. Me is a methyl group, and n has a value 2 or 3. In certain embodiments, R.sub.2 includes at least one functional group. When reacted with a silica surface, the resulting modified surface has a structure: PSiO--?R.sub.1 SiMe--(CH.sub.2).sub.n --SiMeR!--OSiP. PSiO is a surface reacted silica.Type: GrantFiled: June 20, 1997Date of Patent: February 9, 1999Assignee: Hewlett-Packard CompanyInventors: Joseph J. Kirkland, John B. Adams, Jr.
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Patent number: 5108595Abstract: Chromatographic material comprising porous silica microspheres having silanol-enriched and completely silanized surfaces are disclosed. Processes for preparing the specified chromatographic material are also disclosed.Type: GrantFiled: March 8, 1991Date of Patent: April 28, 1992Assignee: E. I. Du Pont de Nemours and CompanyInventors: Joseph J. Kirkland, Jurgen Kohler
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Patent number: 5032266Abstract: Chromatographic materials comprising porous silica microspheres having silanol-enriched and completely silanized surfaces are disclosed. Processes for preparing the specified chromatographic material are also disclosed.Type: GrantFiled: July 19, 1989Date of Patent: July 16, 1991Assignee: E. I. du Pont de Nemours and CompanyInventors: Joseph J. Kirkland, Jurgen Kohler
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Patent number: 4874518Abstract: Chromatographic materials comprising porous silica microspheres having silanol-enriched and completely silanized surfaces are disclosed. Processes for preparing the specified chromatographic material are also disclosed.Type: GrantFiled: December 21, 1988Date of Patent: October 17, 1989Assignee: E. I. Du Pont de Nemours and CompanyInventors: Joseph J. Kirkland, Jurgen Kohler
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Patent number: 4847159Abstract: This invention involves unique compositions consisting of substrates coated with organo-silanes that are sterically protected by a single bulky group. This material consists of an appropriate reactive solid to which is attached a silane whose silicon stom is bonded to a functional group that contains a dimethyl-substituted tertiary carbon.Type: GrantFiled: November 10, 1987Date of Patent: July 11, 1989Assignee: E. I. Du Pont de Nemours and CompanyInventors: Joseph L. Glajch, Joseph J. Kirkland
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Patent number: 4746572Abstract: A bidentate silane containing at least two silicon atoms bridged by certain groups, arranged to form at least a seven member ring system, is formed between the bidentate silane and the atoms to which the silane is covalently attached on the substrate surface.Type: GrantFiled: November 28, 1986Date of Patent: May 24, 1988Assignee: E. I. DuPont de Nemours and CompanyInventors: Joseph L. Glajch, Joseph J. Kirkland
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Patent number: 4705725Abstract: This invention relates to unique stable support structures comprising substrates coated with sterically-protecting monofunctional silanes. This structure consists of an appropriate reactive solid to which a monofunctional silane is covalently bonded that contains at least two sterically-protecting groups attached to the silicon atom of the silane.Type: GrantFiled: November 28, 1986Date of Patent: November 10, 1987Assignee: E. I. Du Pont de Nemours and CompanyInventors: Joseph L. Glajch, Joseph J. Kirkland
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Patent number: 4477492Abstract: There is disclosed a process for preparing superficially porous macroparticles comprising spray drying a specified well-mixed slurry of core macroparticles, colloidal inorganic microparticles and a liquid and sintering the resulting product to cause a 5%-30% decrease in surface area.Type: GrantFiled: April 22, 1983Date of Patent: October 16, 1984Assignee: E. I. Du Pont de Nemours and CompanyInventors: Horacio E. Bergna, Joseph J. Kirkland
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Patent number: 4448679Abstract: A plastic ring has a circumferential groove formed in its outer peripheral surface. The ring is fitted in a bowl-type centrifuge rotor such that the ring's outer surface contacts the inner wall of the rotor. The channel is defined by the groove and rotor wall. The rotor is filled with a compensating liquid to reduce centrifugal stress on the plastic and to reduce leakage from the channel.Type: GrantFiled: November 30, 1981Date of Patent: May 15, 1984Assignee: E. I. Du Pont de Nemours and CompanyInventors: Charles H. Dilks, Jr., Joseph J. Kirkland, Wallace W. Yau