Abstract: Compositions, systems and methods of improving the health of the microbiome of an individual's skin relate to the provision of skin contacting formulations containing beneficial bacteria, postbiotics, metabolites and other microbe components to foster the growth and maintenance of a healthy skin microbiome. One embodiment includes a topical application of Lactobacillus crispatus to ameliorate skin barrier damage and inflammation using unique combinations of probiotics, prebiotics, postbiotics, and other skin-beneficial ingredients, effectively treating inflammatory skin diseases, such as atopic dermatitis, psoriasis and acne, through the production of tryptophan metabolites that act as AHR agonists.

Abstract: A method and system to address the adverse effects on an individual's oral microbiome with the objective of restoring gingival health caused by exposure to sodium lauryl sulfate. Certain embodiments of the present invention facilitate the growth of desired bacteria in a human's mouth to reduce the likelihood of dental caries, halitosis, canker sores, and other oral diseases. Probiotic bacterial, bioactive flavonoid, xylitol and zinc compound compositions, provide effective prevention and treatment options, especially while precluding the use of sodium lauryl sulfate so as to reduce adverse consequences it has on gingival health.

Abstract: Compositions, systems and methods of improving the health of the microbiome of an individual's skin relate to the provision of skin contacting formulations containing beneficial bacteria and other microbe components to foster the growth and maintenance of a healthy skin microbiome. Embodiments include methods for treating an individual suffering from acne valgaris by topically administering a composition that includes live bacteria selected from the group consisting of L reuteri, L johnsonii, L crispatus, C. acnes, and Nitrosomonas eutropha, that have been modified by using a using a clustered regularly interspaced short palindromic repeats (CRISPR) CRISPR associated protein (Cas) system or a CRISPR from Prevotella and Francisella 1 (Cpf1) system to reduce the production of a virulence factor of the bacteria.

Abstract: In some examples, a heat exchanger includes a first flow channel having a first flow channel inlet and a first flow channel outlet. The heat exchanger also includes a second flow channel having a second flow channel inlet and a second flow channel outlet. A fin may separate the first flow channel from the second flow channel. The fin may define at least one aperture configured to allow fluid to flow between the first flow channel and the second flow channel if one of the first flow channel inlet or second flow channel inlet becomes constricted through a buildup of foreign object debris.

Abstract: Provided is a food composition which include a myceliated high-protein food product and methods to make such compositions, which are mixtures of myceliated high-protein food products and other edible materials. A food composition includes dairy alternative products, ready to mix beverages and beverage bases; extruded and extruded/puffed products; sheeted baked goods; meat analogs and extenders; baked goods and baking mixes; granola; and soups/soup bases. Food compositions also include texturized plant protein which can be used for making meat-structured plant protein meat analog or meat extender products. The food compositions have reduced undesirable flavors and reduced undesirable aromas due to use of myceliated high-protein food products as compared to use of similar high-protein material that is not myceliated.

Abstract: Various embodiments of the present invention are directed to the field of treating and preventing osteoporosis, with particular embodiments directed to a method of ameliorating, treating, or preventing osteoporosis in a human subject employing tomatidine, xylitol, rapamycin, etc., as well as modifying an individual's microbiome to reduce the likelihood of osteoporosis.

Abstract: Disclosed herein include systems, methods, compositions, and kits for determining the expression of highly expressed proteins and lowly expressed proteins. In some embodiments, primers allowing generation of separate libraries for abundant AbSeq protein profiling oligonucleotides and scarce AbSeq protein profiling oligonucleotides are provided.

Abstract: Disclosed herein include systems, methods, compositions, and kits for determining the expression of highly expressed proteins and lowly expressed proteins. In some embodiments, primers allowing generation of separate libraries for abundant AbSeq protein profiling oligonucleotides and scarce AbSeq protein profiling oligonucleotides are provided.

Abstract: A heat exchanger includes a plurality of interconnected separator members that respectively include a first surface and an opposite second surface. The separator members respectively include an array of wave features. Also, the separator members are stacked and disposed in an alternating arrangement with the first surfaces of adjacent separator members facing each other and attached at the respective wave features, and with the second surfaces of adjacent separator members facing each other and attached at the respective wave features. The heat exchanger also includes a plurality of first flow passages for first fluid flow and second flow passages for second fluid flow. The second fluid and the first fluid are configured to exchange heat through the separator members.

Abstract: Disclosed herein include systems, methods, compositions, and kits suitable for the use of dextramers in single cell analysis. In some embodiments, one or more primers allowing generation of separate libraries for proteins (e.g., antibodies) and for dextramers are used.

Abstract: Disclosed herein include systems, methods, compositions, and kits for determining the expression of highly expressed proteins and lowly expressed proteins. In some embodiments, primers allowing generation of separate libraries for abundant AbSeq protein profiling oligonucleotides and scarce AbSeq protein profiling oligonucleotides are provided.

Abstract: A heat exchanger includes a separator member that divides a first flow passage from a second flow passage. The heat exchanger also includes a plurality of first hollow members that extend across the first flow passage at respective non-orthogonal angles. The plurality of first hollow members are fluidly connected to the second flow passage. Moreover, the heat exchanger includes a plurality of second hollow members that extend across the second flow passage at respective non-orthogonal angles. The plurality of second hollow members are fluidly connected to the first flow passage.

Abstract: A heat exchanger includes a plurality of interconnected separator members that respectively include a first surface and an opposite second surface. The separator members respectively include an array of wave features. Also, the separator members are stacked and disposed in an alternating arrangement with the first surfaces of adjacent separator members facing each other and attached at the respective wave features, and with the second surfaces of adjacent separator members facing each other and attached at the respective wave features. The heat exchanger also includes a plurality of first flow passages for first fluid flow and second flow passages for second fluid flow. The second fluid and the first fluid are configured to exchange heat through the separator members.

Abstract: A heat exchanger includes a plurality of interconnected separator members that respectively include a first surface and an opposite second surface. The separator members respectively include an array of wave features. Also, the separator members are stacked and disposed in an alternating arrangement with the first surfaces of adjacent separator members facing each other and attached at the respective wave features, and with the second surfaces of adjacent separator members facing each other and attached at the respective wave features. The heat exchanger also includes a plurality of first flow passages for first fluid flow and second flow passages for second fluid flow. The second fluid and the first fluid are configured to exchange heat through the separator members.

Abstract: A heat exchanger includes a separator member that divides a first flow passage from a second flow passage. The heat exchanger also includes a plurality of first hollow members that extend across the first flow passage at respective non-orthogonal angles. The plurality of first hollow members are fluidly connected to the second flow passage. Moreover, the heat exchanger includes a plurality of second hollow members that extend across the second flow passage at respective non-orthogonal angles. The plurality of second hollow members are fluidly connected to the first flow passage.

Abstract: A core to receive an air flow having foreign object debris (FOD) has an inlet plane at which the air flow can enter the core, a fin element having a fin configuration, and a first protective component. The first protective component is constructed of a material and has a first protective configuration sufficient to repel FOD.

Abstract: A core to receive an air flow having foreign object debris (FOD) has an inlet plane at which the air flow can enter the core, a fin element having a fin configuration, and a first protective component. The first protective component is constructed of a material and has a first protective configuration sufficient to repel FOD.

Abstract: A heat exchanger includes a separator member that divides a first flow passage from a second flow passage. The heat exchanger also includes a plurality of first hollow members that extend across the first flow passage at respective non-orthogonal angles. The plurality of first hollow members are fluidly connected to the second flow passage. Moreover, the heat exchanger includes a plurality of second hollow members that extend across the second flow passage at respective non-orthogonal angles. The plurality of second hollow members are fluidly connected to the first flow passage.

Abstract: A heat exchanger includes a plurality of interconnected separator members that respectively include a first surface and an opposite second surface. The separator members respectively include an array of wave features. Also, the separator members are stacked and disposed in an alternating arrangement with the first surfaces of adjacent separator members facing each other and attached at the respective wave features, and with the second surfaces of adjacent separator members facing each other and attached at the respective wave features. The heat exchanger also includes a plurality of first flow passages for first fluid flow and second flow passages for second fluid flow. The second fluid and the first fluid are configured to exchange heat through the separator members.

Abstract: A heat exchanger includes a separator member that divides a first flow passage from a second flow passage. The heat exchanger also includes a plurality of first hollow members that extend across the first flow passage at respective non-orthogonal angles. The plurality of first hollow members are fluidly connected to the second flow passage. Moreover, the heat exchanger includes a plurality of second hollow members that extend across the second flow passage at respective non-orthogonal angles. The plurality of second hollow members are fluidly connected to the first flow passage.