Patents by Inventor Joseph Knoll

Joseph Knoll has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6391914
    Abstract: A novel optically pure (−)-1-(Benzofuran-2-yl)-2-propylaminopentane as represented by the following formula, which contains no (+)-isomer, and the pharmaceutically acceptable acid salt thereof. These compounds have excellent CAE effect (catecholaminergic activity enhancer effect) which is the enhancing action of neurotransmitter catecholamine release, and are useful as psychotropic composition, antidepressants, composition for treating Parkinson's disease and/or Alzheimer's disease.
    Type: Grant
    Filed: June 16, 2000
    Date of Patent: May 21, 2002
    Assignee: Fujimoto Brothers Co., Ltd.
    Inventors: Joseph Knoll, Fumio Yoneda, Hironori Ohde, Masatoshi Sakae, Toshiaki Moto, Takashi Ando, Seiichiro Shimazu, Kazue Takahata
  • Patent number: 6214859
    Abstract: Ethylamine derivatives of the formula (I): (wherein R1 is hydrogen, hydroxyl, lower alkoxy or halogen; R2 is alkyl having 2 to 5 carbon atoms; R3 is hydrogen, alkyl having 2 to 5 carbon atoms, alkylcarbonyl having 2 to 5 carbon atoms, aryl having 6 to 10 carbon atoms or arylalkyl having 7 to 11 carbon atoms; the ring is a bicyclic compound which consists of at least one benzene ring and may comprise a saturated or unsaturated five- or six-membered ring which may or may not have heteroatoms, providing that when the ring is indole or 1,3-benzodioxole, R2 and R3 do not constitute, at the same time, two carbon atoms members, and when R3 is hydrogen, the ring is a bicyclic compound which is not indole, benzothiophene or benzodioxole and R2 is alkyl having 3 to 5 carbon atoms and pharmaceutically acceptable acid addition salts thereof. These compounds are promising as psychotropic drugs, antidepressants, drugs for Parkinson's disease and/or drugs for Alzeimer's disease.
    Type: Grant
    Filed: July 12, 1999
    Date of Patent: April 10, 2001
    Assignee: Fujimoto Brothers Co., Ltd.
    Inventors: Fumio Yoneda, Joseph Knoll, Hironori Ode, Masatoshi Sakae, Masanori Katurada, Toshiaki Moto, Takashi Ando, Seiichiro Shimazu, Kazue Takahata, Michitaro Fujimoto
  • Patent number: 4763835
    Abstract: There is a rail connecting and alignment device for a railway track disclosed for interconnecting I-shaped rail members. The connecting and aligning device is vertically supported on rail ties, and in turn supports the I-shaped rail member which may lie such that abutting ends are located over a space between rail ties, and the abutting ends are located within the connecting members.The present invention is concerned with the alignment and connection of railway track. More specifically, the invention is an improvement relating to a rail connecting and alignment device for a railway track and for interconnecting I-shaped rail members which constitute the track. There is a plurality of spaced apart rail tie members, which normally lie upon a rail tie support bed. The tie members are able to support the railway track. A device is provided for vertically supporting a series of the I-shaped rail members so that abutting ends of the rail members may be located over a span between the spaced apart rail tie members.
    Type: Grant
    Filed: September 12, 1986
    Date of Patent: August 16, 1988
    Inventor: Joseph Knoll