Patents by Inventor Joseph M. Castellano

Joseph M. Castellano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR TREATING AGING-ASSOCIATED CONDITIONS
    Publication number: 20220016224
    Abstract: Methods of treating an adult mammal for an aging-associated condition are provided. Aspects of the methods include enhancing a TIMP activity, e.g., a TIMP2 activity, in the mammal in a manner sufficient to treat the adult mammal for the aging-associated condition. Also provided are compositions for use in practicing methods of the invention. A variety of aging-associated conditions may be treated by practice of the methods, which conditions include cognitive impairments.
    Type: Application
    Filed: October 8, 2021
    Publication date: January 20, 2022
    Inventors: Anton Wyss-Coray, Joseph M. Castellano
  • Methods and compositions for treating aging-associated conditions
    Patent number: 11141469
    Abstract: Methods of treating an adult mammal for an aging-associated condition are provided. Aspects of the methods include enhancing a TIMP activity, e.g., a TIMP2 activity, in the mammal in a manner sufficient to treat the adult mammal for the aging-associated condition. Also provided are compositions for use in practicing methods of the invention. A variety of aging-associated conditions may be treated by practice of the methods, which conditions include cognitive impairments.
    Type: Grant
    Filed: April 7, 2020
    Date of Patent: October 12, 2021
    Assignees: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY, The United States of America as represented by the Department of Veterans Affairs
    Inventors: Anton Wyss-Coray, Joseph M. Castellano
  • METHODS AND COMPOSITIONS FOR TREATING AGING-ASSOCIATED CONDITIONS
    Publication number: 20200352994
    Abstract: Methods and compositions are provided for treating a subject for aging-associated conditions, e.g., cognitive impairment conditions. Aspects of the methods include administering a young plasma-comprising blood product to an individual in need thereof, e.g., an individual suffering from or at risk of developing the aging-associated condition, e.g., aging-associated cognitive impairment. Also provided are compositions and kits thereof that find use in practicing methods of the invention.
    Type: Application
    Filed: May 21, 2020
    Publication date: November 12, 2020
    Inventors: Anton Wyss-Coray, Saul A. Villeda, Joseph M. Castellano, Jinte Middeldorp, Martin S. Angst, Jian Luo
  • METHODS AND COMPOSITIONS FOR TREATING AGING-ASSOCIATED CONDITIONS
    Publication number: 20200254075
    Abstract: Methods of treating an adult mammal for an aging-associated condition are provided. Aspects of the methods include enhancing a TIMP activity, e.g., a TIMP2 activity, in the mammal in a manner sufficient to treat the adult mammal for the aging-associated condition. Also provided are compositions for use in practicing methods of the invention. A variety of aging-associated conditions may be treated by practice of the methods, which conditions include cognitive impairments.
    Type: Application
    Filed: April 7, 2020
    Publication date: August 13, 2020
    Inventors: Anton Wyss-Coray, Joseph M. Castellano
  • Methods and compositions for treating aging-associated conditions
    Patent number: 10688130
    Abstract: Methods and compositions are provided for treating a subject for aging-associated conditions, e.g., cognitive impairment conditions. Aspects of the methods include administering a young plasma-comprising blood product to an individual in need thereof, e.g., an individual suffering from or at risk of developing the aging-associated condition, e.g., aging-associated cognitive impairment. Also provided are compositions and kits thereof that find use in practicing methods of the invention.
    Type: Grant
    Filed: December 5, 2014
    Date of Patent: June 23, 2020
    Assignees: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY, U.S. GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
    Inventors: Anton Wyss-Coray, Saul A. Villeda, Joseph M. Castellano, Jinte Middeldorp, Martin S. Angst, Jian Luo
  • Methods and compositions for treating aging-associated conditions
    Patent number: 10617744
    Abstract: Methods of treating an adult mammal for an aging-associated condition are provided. Aspects of the methods include enhancing a TIMP activity, e.g., a TIMP2 activity, in the mammal in a manner sufficient to treat the adult mammal for the aging-associated condition. Also provided are compositions for use in practicing methods of the invention. A variety of aging-associated conditions may be treated by practice of the methods, which conditions include cognitive impairments.
    Type: Grant
    Filed: June 6, 2016
    Date of Patent: April 14, 2020
    Assignees: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY, U.S. GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS
    Inventors: Anton Wyss-Coray, Joseph M. Castellano
  • METHODS AND COMPOSITIONS FOR TREATING AGING-ASSOCIATED CONDITIONS
    Publication number: 20180353578
    Abstract: Methods of treating an adult mammal for an aging-associated condition are provided. Aspects of the methods include enhancing a TIMP activity, e.g., a TIMP2 activity, in the mammal in a manner sufficient to treat the adult mammal for the aging-associated condition. Also provided are compositions for use in practicing methods of the invention. A variety of aging-associated conditions may be treated by practice of the methods, which conditions include cognitive impairments.
    Type: Application
    Filed: June 6, 2016
    Publication date: December 13, 2018
    Inventors: Anton Wyss-Coray, Joseph M. Castellano
  • METHODS AND COMPOSITIONS FOR TREATING AGING-ASSOCIATED CONDITIONS
    Publication number: 20150157664
    Abstract: Methods and compositions are provided for treating a subject for aging-associated conditions, e.g., cognitive impairment conditions. Aspects of the methods include administering a young plasma-comprising blood product to an individual in need thereof, e.g., an individual suffering from or at risk of developing the aging-associated condition, e.g., aging-associated cognitive impairment. Also provided are compositions and kits thereof that find use in practicing methods of the invention.
    Type: Application
    Filed: December 5, 2014
    Publication date: June 11, 2015
    Inventors: Anton Wyss-Coray, Saul A. Villeda, Joseph M. Castellano, Jinte Middeldorp, Martin S. Angst, Jian Luo