Patents by Inventor Joseph M. Pawlak

Joseph M. Pawlak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODIFIED PICTET-SPENGLER REACTION AND PRODUCTS PREPARED THEREFROM
    Publication number: 20090312548
    Abstract: A method of introducing a second stereogenic center into a tetrahydro-?-carboline have two stereogenic centers using a modified Pictet-Spengler reaction is disclosed. The method provides a desired cis- or trans-isomer in high yield and purity, and in short processes times.
    Type: Application
    Filed: June 18, 2009
    Publication date: December 17, 2009
    Inventors: Mark W. Orme, Michael J. Martinelli, Christopher W. Doecke, Joseph M. Pawlak, Erik C. Chelius
  • Modified Pictet-Spengler reaction and products prepared therefrom
    Patent number: 7550479
    Abstract: A method of introducing a second stereogenic center into a tetrahydro-?-carboline have two stereogenic centers using a modified Pictet-Spengler reaction is disclosed. The method provides a desired cis- or trans-isomer in high yield and purity, and in short processes times.
    Type: Grant
    Filed: July 14, 2003
    Date of Patent: June 23, 2009
    Assignee: Lilly ICOS LLC
    Inventors: Mark W. Orme, Michael J. Martinelli, Christopher W. Doecke, Joseph M. Pawlak, Erik C. Chelius
  • Process and novel intermediates
    Patent number: 6020512
    Abstract: Novel processes and intermediates useful in the preparation of Cryptophycin compounds are disclosed.
    Type: Grant
    Filed: February 25, 1998
    Date of Patent: February 1, 2000
    Assignees: Eli Lilly and Company, Wayne State University, University of Hawaii
    Inventors: Michael J. Martinelli, Eric D Moher, Naresh K Nayyar, Joseph M Pawlak, David W Hoard, Vien V Khau, John E Toth, David L Varie