Patents by Inventor Joseph M. Sheridan

Joseph M. Sheridan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR THE BIOSYNTHESIS OF VANILLIN OR VANILLIN BETA-D-GLUCOSIDE
    Publication number: 20210230646
    Abstract: Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express a mutant AROM polypeptide and/or mutant catechol-O-methyltransferase polypeptide alone or in combination with one or more vanillin biosynthetic enzymes or UDP-glycosyltransferases (UGTs). Such microorganisms, plants, or plant cells can produce vanillin or vanillin beta-D-glucoside.
    Type: Application
    Filed: April 14, 2021
    Publication date: July 29, 2021
    Inventors: Joergen HANSEN, Esben Halkjaer HANSEN, Honey POLUR, Joseph M. SHERIDAN, Jonathan R. HEAL, William D.O. HAMILTON
  • Compositions and methods for the biosynthesis of vanillin or vanillin beta-d-glucoside
    Patent number: 11008592
    Abstract: Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express a mutant AROM polypeptide and/or mutant catechol-O-methyltransferase polypeptide alone or in combination with one or more vanillin biosynthetic enzymes or UDP-glycosyltransferases (UGTs). Such microorganisms, plants, or plant cells can produce vanillin or vanillin beta-D-glucoside.
    Type: Grant
    Filed: January 9, 2019
    Date of Patent: May 18, 2021
    Assignees: INTERNATIONAL FLAVORS & FRAGRANCES INC., EVOLVA SA
    Inventors: Joergen Hansen, Esben Halkjaer Hansen, Honey Polur, Joseph M. Sheridan, Jonathan R. Heal, William D. O. Hamilton
  • Casein kinase 1 delta inhibitor
    Patent number: 10815230
    Abstract: The present invention provides 2-Methyl-amino-3-[(4-fluorophenyl)carbonyl]indolizine-1-carboxamide of formula (I) or a pharmaceutically acceptable salt thereof; and its therapeutic uses in the treatment of neurodegenerative disorders, in particular tauopathies and most preferably in the treatment of Alzheimer's disease.
    Type: Grant
    Filed: May 13, 2016
    Date of Patent: October 27, 2020
    Assignee: ELECTROPHORETICS LIMITED
    Inventors: Ian H. Pike, Karsten Kuhn, Stefan Kienle, William D. O. Hamilton, Jonathan R. Heal, Joseph M. Sheridan
  • COMPOSITIONS AND METHODS FOR THE BIOSYNTHESIS OF VANILLIN OR VANILLIN BETA-D-GLUCOSIDE
    Publication number: 20190136270
    Abstract: Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express a mutant AROM polypeptide and/or mutant catechol-O-methyltransferase polypeptide alone or in combination with one or more vanillin biosynthetic enzymes or UDP-glycosyltransferases (UGTs). Such microorganisms, plants, or plant cells can produce vanillin or vanillin beta-D-glucoside.
    Type: Application
    Filed: January 9, 2019
    Publication date: May 9, 2019
    Inventors: Joergen HANSEN, Esben Halkjaer HANSEN, Honey POLUR, Joseph M. SHERIDAN, Jonathan R. HEAL, William D.O. HAMILTON
  • Compositions and methods for the biosynthesis of vanillan or vanillin beta-D-glucoside
    Patent number: 10208293
    Abstract: Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express a mutant AROM polypeptide and/or mutant catechol-O-methyltransferase polypeptide alone or in combination with one or more vanillin biosynthetic enzymes or UDP-glycosyltransferases (UGTs). Such microorganisms, plants, or plant cells can produce vanillin or vanillin beta-D-glucoside.
    Type: Grant
    Filed: August 7, 2012
    Date of Patent: February 19, 2019
    Assignees: International Flavors & Fragrances Inc., Evolva SA
    Inventors: Joergen Hansen, Esben Halkjaer Hansen, Honey Polur, Joseph M. Sheridan, Jonathan R. Heal, William D. O. Hamilton
  • Anthocyanins with specific properties
    Patent number: 10119154
    Abstract: The present disclosure provides methods for identifying anthocyanins with improved stability, color, or hue using a screening method, and producing anthocyanins with improved stability, color, or hue in, for example, host cells comprising one or more heterologous glycosyltransferase nucleic acid molecules and one or more heterologous acyltransferase nucleic acid molecules.
    Type: Grant
    Filed: December 23, 2013
    Date of Patent: November 6, 2018
    Assignee: Evolva SA
    Inventors: Jorgen Hansen, Patricia Hoyle, Michael Naesby, Joseph M. Sheridan, Jonathan R. Heal
  • A CASEIN KINASE 1 DELTA INHIBITOR
    Publication number: 20180186786
    Abstract: The present invention provides 2-Methyl-amino-3-[(4-fluorophenyl)carbonyl]indolizine-1-carboxamide of formula (I) or a pharmaceutically acceptable salt thereof; and its therapeutic uses in the treatment of neurodegenerative disorders, in particular tauopathies and most preferably in the treatment of Alzheimer's disease.
    Type: Application
    Filed: May 13, 2016
    Publication date: July 5, 2018
    Applicant: ELECTROPHORETICS LIMITED
    Inventors: Ian H. Pike, Karsten Kuhn, Stefan Kienle, William D.O. Hamilton, Jonathan R. Heal, Joseph M. Sheridan
  • Casein kinase 1? (CK 1?) inhibitors
    Patent number: 9789111
    Abstract: The invention relates to pharmaceutical compositions having casein kinase 1 delta (CK1?) inhibitors and to the use of the inhibitors in the treatment of neurodegenerative disorders such as Alzheimer's disease.
    Type: Grant
    Filed: April 2, 2015
    Date of Patent: October 17, 2017
    Assignee: ELECTROPHORETICS LIMITED
    Inventors: Joseph M. Sheridan, Jonathan R. Heal, William D. O. Hamilton, Ian H. Pike
  • Casein kinase 1delta (CK1delta) inhibitors
    Patent number: 9763947
    Abstract: The invention relates to pharmaceutical compositions having casein kinase 1 delta (CK1?) inhibitors and to the use of the inhibitors in the treatment of neurodegenerative disorders such as Alzheimer's disease.
    Type: Grant
    Filed: September 1, 2015
    Date of Patent: September 19, 2017
    Assignee: ELECTROPHORETICS LIMITED
    Inventors: Joseph M. Sheridan, Jonathan R. Heal, William D. O. Hamilton, Ian H. Pike
  • CASEIN KINASE 1delta (CK 1delta) INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES SUCH AS TAUOPATHIES
    Publication number: 20160354375
    Abstract: The invention relates to pharmaceutical compositions comprising casein kinase 1 delta (CK1?) and to the use of said inhibitors in the treatment of neurodegenerative disorders such as Alzheimer's disease.
    Type: Application
    Filed: June 2, 2016
    Publication date: December 8, 2016
    Applicant: Electrophoretics Limited
    Inventors: Joseph M. Sheridan, Jonathan R. Heal, William D.O. Hamilton, Ian Pike
  • Quick release roller sleeve mounting hub
    Patent number: 9341213
    Abstract: A quick release roller sleeve and mounting hub assembly is described for use with high speed roller machines. The assembly includes an outer flange plate that can be detached from the assembly in order for the roller sleeve to be dismounted and a new roller sleeve mounted as the existing roller sleeve becomes worn and needs to be replaced. The quick release permits the mounting hub and other parts of the assembly to remain in their aligned configuration and positions while only exchanging the roller sleeve portion of the assembly.
    Type: Grant
    Filed: October 19, 2012
    Date of Patent: May 17, 2016
    Assignee: FRC Holding Corp.
    Inventor: Joseph M. Sheridan
  • CASEIN KINASE 1DELTA (CK 1DELTA) INHIBITORS
    Publication number: 20160058745
    Abstract: The invention relates to pharmaceutical compositions having casein kinase 1 delta (CK1?) inhibitors and to the use of the inhibitors in the treatment of neurodegenerative disorders such as Alzheimer's disease.
    Type: Application
    Filed: September 1, 2015
    Publication date: March 3, 2016
    Applicant: Electrophoretics Limited
    Inventors: Joseph M. Sheridan, Jonathan R. Heal, William D.O. Hamilton, Ian H. Pike
  • Anthocyanins with Specific Properties
    Publication number: 20150344920
    Abstract: The present disclosure provides methods for identifying anthocyanins with improved stability, color, or hue using a screening method, and producing anthocyanins with improved stability, color, or hue in, for example, host cells comprising one or more heterologous glycosyltransferase nucleic acid molecules and one or more heterologous acyltransferase nucleic acid molecules.
    Type: Application
    Filed: December 23, 2013
    Publication date: December 3, 2015
    Applicant: Evolva SA
    Inventors: Jorgen Hansen, Patricia Hoyle, Michael Naesby, Joseph M. Sheridan, Jonathan R. Heal
  • CASEIN KINASE 1DELTA (CK 1DELTA) INHIBITORS
    Publication number: 20150209368
    Abstract: The invention relates to pharmaceutical compositions having casein kinase 1 delta (CK1?) inhibitors and to the use of the inhibitors in the treatment of neurodegenerative disorders such as Alzheimer's disease.
    Type: Application
    Filed: April 2, 2015
    Publication date: July 30, 2015
    Applicant: Electrophoretics Limited
    Inventors: Joseph M. Sheridan, Jonathan R. Heal, William D.O. Hamilton, Ian H. Pike
  • COMPOSITIONS AND METHODS FOR THE BIOSYNTHESIS OF VANILLAN OR VANILLIN BETA-D-GLUCOSIDE
    Publication number: 20140245496
    Abstract: Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to express a mutant AROM polypeptide and/or mutant catechol-O-methyltransferase polypeptide alone or in combination with one or more vanillin biosynthetic enzymes or UDP-glycosyltransferases (UGTs). Such microorganisms, plants, or plant cells can produce vanillin or vanillin beta-D-glucoside.
    Type: Application
    Filed: August 7, 2012
    Publication date: August 28, 2014
    Applicants: EVOLVA SA, INTERNATIONAL FLAVORS & FRAGRANCES INC.
    Inventors: Joergen Hansen, Esben Halkjaer Hansen, Honey Polur, Joseph M. Sheridan, Jonathan R. Heal, William D.O. Hamilton
  • Quick Release Roller Sleeve Mounting Hub
    Publication number: 20140113784
    Abstract: A quick release roller sleeve and mounting hub assembly is described for use with high speed roller machines. The assembly includes an outer flange plate that can be detached from the assembly in order for the roller sleeve to be dismounted and a new roller sleeve mounted as the existing roller sleeve becomes worn and needs to be replaced. The quick release permits the mounting hub and other parts of the assembly to remain in their aligned configuration and positions while only exchanging the roller sleeve portion of the assembly.
    Type: Application
    Filed: October 19, 2012
    Publication date: April 24, 2014
    Inventor: Joseph M. Sheridan
  • CASEIN KINASE 1delta (CK 1delta) INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODE-GENERATIVE DISEASES SUCH AS TAUOPATHIES
    Publication number: 20140031547
    Abstract: The invention relates to pharmaceutical compositions comprising casein kinase 1 delta (CK1?) and to the use of said inhibitors in the treatment of neurodegenerative disorders such as Alzheimer's disease.
    Type: Application
    Filed: December 14, 2011
    Publication date: January 30, 2014
    Inventors: Joseph M. Sheridan, Jonathan R. Heal, William D.O. Hamilton, Ian Pike
  • CASEIN KINASE 1DELTA (CK 1DELTA) INHIBITORS
    Publication number: 20140018540
    Abstract: The invention relates to pharmaceutical compositions comprising casein kinase 1 delta (CK1?) and to the use of said inhibitors in the treatment of neurodegenerative disorders such as Alzheimer's disease.
    Type: Application
    Filed: December 14, 2011
    Publication date: January 16, 2014
    Inventors: Joseph M. Sheridan, Jonathan R. Heal, William D.O. Hamilton, Ian Pike