Patents by Inventor Joseph Michienzi
Joseph Michienzi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11242871Abstract: A liquid chromatography solvent pump includes at least one motor, a first piston, a second piston, and a continuously variable output drive system coupling the at least one motor to at least one of the first and second pistons. The first piston and the second piston are configured to deliver a flow of solvent in a liquid chromatography system.Type: GrantFiled: September 17, 2019Date of Patent: February 8, 2022Assignee: WATERS TECHNOLOGIES CORPORATIONInventors: Jeffrey Musacchio, Michael Eggertson, Joseph Michienzi
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Patent number: 11162517Abstract: Disclosed is a liquid chromatography solvent pump including a motor, a first piston, a second piston, and a variable output drive system coupling the motor to at least one of the first piston and the second piston. The variable output drive system includes a gearbox configured to provide a non-equal ratio between an input from the motor and an output delivered to at least one of the first piston and the second piston. The first piston and the second piston are configured to deliver a flow of solvent in a liquid chromatography system.Type: GrantFiled: September 17, 2019Date of Patent: November 2, 2021Assignee: WATERS TECHNOLOGIES CORPORATIONInventors: Jeffrey Musacchio, Joseph Michienzi
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Patent number: 10823713Abstract: The present disclosure generally relates to systems, methods and devices for providing pressurized solvent flow in chromatography systems.Type: GrantFiled: December 19, 2017Date of Patent: November 3, 2020Assignee: Waters Technologies CorporationInventors: Wade P. Leveille, Jonathan L. Belanger, Moon Chul Jung, Abhijit Tarafder, Joseph Michienzi, Keith Fadgen, Kevin Wyndham, Xiangjin Song
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Publication number: 20200200716Abstract: The present disclosure relates to methodologies, systems, and devices for extracting CO2 from a mobile phase within a chromatography or extraction system. A mobile phase pump can pump a CO2-based mobile phase through a chromatography column, and a BPR can decompress the mobile phase downstream of the column. Decompressed CO2 can be extracted from the mobile phase using a gas-liquid separator located downstream of the chromatography column. A detector located downstream of the gas-liquid separator can then analyze a substantially liquid mobile phase.Type: ApplicationFiled: December 18, 2019Publication date: June 25, 2020Applicant: Waters Technologies CorporationInventors: Michael O. Fogwill, Sebastien Besner, Scott Kelley, Joseph Michienzi
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Publication number: 20200200720Abstract: The present disclosure relates to optical flow cells for use in chromatography or extraction systems. The optical flow cells include an inlet portion configured to receive a highly compressible fluid and an inlet transition portion or gasket having an internal volume and internal geometry configured to receive the highly compressible fluid from the inlet portion. The optical flow cell also includes an optical path portion configured to receive the highly compressible fluid from the inlet transition portion and direct the highly compressible fluid along an optical flow path. The internal volume and the internal geometry of the inlet transition portion configured to minimize turbulence and eddies within the highly compressible fluid as it travels through the optical flow path.Type: ApplicationFiled: December 18, 2019Publication date: June 25, 2020Applicant: Waters Technologies CorporationInventors: Michael O. Fogwill, Sebastien Besner, Scott Kelley, Joseph Michienzi
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Publication number: 20200088221Abstract: A liquid chromatography solvent pump includes at least one motor, a first piston, a second piston, and a continuously variable output drive system coupling the at least one motor to at least one of the first and second pistons. The first piston and the second piston are configured to deliver a flow of solvent in a liquid chromatography system.Type: ApplicationFiled: September 17, 2019Publication date: March 19, 2020Inventors: Jeffrey Musacchio, Michael Eggertson, Joseph Michienzi
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Publication number: 20200088220Abstract: Disclosed is a liquid chromatography solvent pump including a motor, a first piston, a second piston, and a variable output drive system coupling the motor to at least one of the first piston and the second piston. The variable output drive system includes a gearbox configured to provide a non-equal ratio between an input from the motor and an output delivered to at least one of the first piston and the second piston. The first piston and the second piston are configured to deliver a flow of solvent in a liquid chromatography system.Type: ApplicationFiled: September 17, 2019Publication date: March 19, 2020Inventors: Jeffrey Musacchio, Joseph Michienzi
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Publication number: 20180202980Abstract: The present disclosure generally relates to systems, methods and devices for providing pressurized solvent flow in chromatography systems.Type: ApplicationFiled: December 19, 2017Publication date: July 19, 2018Inventors: Wade P. Leveille, Jonathan L. Belanger, Moon Chul Jung, Abhijit Tarafder, Joseph Michienzi, Keith Fadgen, Kevin Wyndham, Xiangjin Song
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Patent number: 9304116Abstract: An apparatus includes a portable housing and a plurality of separately operable microfluidic emitters disposed within the housing. Each microfluidic emitter h an inlet for receiving a liquid and an outlet for emitting a spray. Each microfluidic emitter is movable within the portable housing between a first position in which the outlet of that microfluidic emitter is fully retracted within the portable housing and a second position in which the outlet of that microfluidic emitter projects out of the portable housing. The portable housing with the multiple emitters is adapted to be detachably coupled to another housing portion. This housing portion includes a microfluidic substrate with a channel for transporting an eluent and an outlet aperture for emitting the eluent. The inlet of one of the emitters is detachably coupled to the outlet aperture of the microfluidic substrate.Type: GrantFiled: April 13, 2012Date of Patent: April 5, 2016Assignee: Waters Technologies CorporationInventors: James P. Murphy, Joseph Michienzi
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Patent number: 9169934Abstract: A method for switching a high pressure fluid includes applying a fixed force between a planar surface of a rotor and a planar surface of a stator. The planar surface of the rotor includes a fluidic channel and the planar surface of the stator has a pair of ports to receive and provide the fluid. A control signal is applied to a linear actuator coupled to the rotor to generate a controllable force between the planar surfaces of the rotor and stator. The control signal is responsive to a rotational state of the rotor. The total force between the planar surfaces of the rotor and the stator is substantially equal to a sum of the fixed force and the controllable force. The method reduces the wear and extends the lifetime of components in a rotary shear seal valve.Type: GrantFiled: April 24, 2012Date of Patent: October 27, 2015Assignee: Waters Technologies CorporationInventors: Bernard Bunner, Joseph Michienzi, Keith Fadgen
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Patent number: 8794676Abstract: A connector for connecting a first conduit to a second conduit including a body having a passageway therethrough, a first cavity and a second cavity, a first sealing member, a second sealing member, a first compression, a second compression fitting, a first set of one or more keys and one or more mated key ways for preventing rotation of the first conduit when the first sealing member is compressed, and a second set of one or more keys and one or more mated key ways for preventing rotation of the second conduit when the second sealing member is compressed, wherein each of the first cavity and the second cavity in the body is configured to receive one of the sealing members or a detachable holder configured to receive one of the sealing members.Type: GrantFiled: May 21, 2009Date of Patent: August 5, 2014Assignee: Waters Technologies CorporationInventors: James P. Murphy, Joseph Michienzi, David Prentice, Sylvain Cormier
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Publication number: 20140053910Abstract: Described are a rotary shear seal valve and a method for switching a high pressure fluid. The method includes applying a fixed force between a planar surface of a rotor and a planar surface of a stator. The planar surface of the rotor includes a fluidic channel and the planar surface of the stator has a pair of ports to receive and provide the fluid. A control signal is applied to a linear actuator coupled to the rotor to generate a controllable force between the planar surfaces of the rotor and stator. The control signal is responsive to a rotational state of the rotor. The total force between the planar surfaces of the rotor and the stator is substantially equal to a sum of the fixed force and the controllable force. The method reduces the wear and extends the lifetime of components in a rotary shear seal valve.Type: ApplicationFiled: April 24, 2012Publication date: February 27, 2014Applicant: WATERS TECHNOLOGIES CORPORATIONInventors: Bernard Bunner, Joseph Michienzi, Keith Fadgen
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Publication number: 20140047907Abstract: An apparatus includes a portable housing and a plurality of separately operable microfluidic emitters disposed within the housing. Each microfluidic emitter h an inlet for receiving a liquid and an outlet for emitting a spray. Each microfluidic emitter is movable within the portable housing between a first position in which the outlet of that microfluidic emitter is fully retracted within the portable housing and a second position in which the outlet of that microfluidic emitter projects out of the portable housing. The portable housing with the multiple emitters is adapted to be detachably coupled to another housing portion. This housing portion includes a microfluidic substrate with a channel for transporting an eluent and an outlet aperture for emitting the eluent. The inlet of one of the emitters is detachably coupled to the outlet aperture of the microfluidic substrate.Type: ApplicationFiled: April 13, 2012Publication date: February 20, 2014Applicant: WATERS TECHNOLOGIES CORPORATIONInventors: James P. Murphy, Joseph Michienzi
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Publication number: 20110198842Abstract: A connector for connecting a first conduit to a second conduit including a body having a passageway therethrough, a first cavity and a second cavity, a first sealing member, a second sealing member, a first compression, a second compression fitting, a first set of one or more keys and one or more mated key ways for preventing rotation of the first conduit when the first sealing member is compressed, and a second set of one or more keys and one or more mated key ways for preventing rotation of the second conduit when the second sealing member is compressed, wherein each of the first cavity and the second cavity in the body is configured to receive one of the sealing members or a detachable holder configured to receive one of the sealing members.Type: ApplicationFiled: May 21, 2009Publication date: August 18, 2011Applicant: WATERS TECHNOLOGIES CORPORATIONInventors: James P. Murphy, Joseph Michienzi, David Prentice, Sylvain Cormier
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Publication number: 20090321356Abstract: A high-performance liquid-chromatography apparatus includes a substrate that defines a separation column in fluidic communication with an inlet port of the processing unit. The processing unit is formed of sintered inorganic particles. The apparatus also includes a pump that delivers a solvent to the inlet port at a pressure sufficient for high-performance liquid-chromatography.Type: ApplicationFiled: March 19, 2007Publication date: December 31, 2009Applicant: WATERS INVESTMENTS LIMITEDInventors: Geoff C. Gerhardt, Joseph Michienzi, Christopher C. Benevides