Patents by Inventor Joseph Moskal

Joseph Moskal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NDMA RECEPTOR MODULATORS AND USES THEREOF
    Publication number: 20190135862
    Abstract: Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorders, such as learning, cognitive activities, and analgesia, particularly in alleviating and/or reducing neuropathic pain. Orally available formulations and other pharmaceutically acceptable delivery forms of the compounds, including intravenous formulations, are also disclosed.
    Type: Application
    Filed: July 6, 2018
    Publication date: May 9, 2019
    Inventors: M. Amin Khan, Joseph Moskal
  • METHOD OF FABRICATING CUSTOMIZED PATIENT-SPECIFIC BONE CUTTING BLOCKS
    Publication number: 20190110841
    Abstract: A number of orthopaedic surgical instruments are also disclosed. A method, apparatus, and system for fabricating such instruments are also disclosed.
    Type: Application
    Filed: December 11, 2018
    Publication date: April 18, 2019
    Inventors: Luke J. Aram, William Bugbee, Charles A. Engh, JR., Joseph Moskal, Mark Pagnano, Michael Swank, Bryan Rose, Jose F. Guzman
  • Method of fabricating customized patient-specific bone cutting blocks
    Patent number: 10149722
    Abstract: A number of orthopedic surgical instruments are also disclosed. A method, apparatus, and system for fabricating such instruments are also disclosed.
    Type: Grant
    Filed: February 23, 2011
    Date of Patent: December 11, 2018
    Assignee: DEPUY SYNTHES PRODUCTS, INC.
    Inventors: Luke J. Aram, William Bugbee, Charles A. Engh, Jr., Joseph Moskal, Mark Pagnano, Michael Swank, Bryan Rose, Jose F. Guzman
  • NMDA RECEPTOR MODULATORS AND USES THEREOF
    Publication number: 20180237474
    Abstract: Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorders, such as learning, cognitive activities, and analgesia, particularly in alleviating and/or reducing neuropathic pain. Orally available formulations and other pharmaceutically acceptable delivery forms of the compounds, including intravenous formulations, are also disclosed.
    Type: Application
    Filed: February 14, 2018
    Publication date: August 23, 2018
    Inventors: Joseph Moskal, M. Amin Khan
  • Customized patient-specific bone cutting blocks
    Patent number: 9786022
    Abstract: A number of orthopaedic surgical instruments are disclosed. A method, apparatus, and system for fabricating such instruments are also disclosed.
    Type: Grant
    Filed: February 23, 2011
    Date of Patent: October 10, 2017
    Assignee: DEPUY SYNTHES PRODUCTS, INC.
    Inventors: Luke J. Aram, William Bugbee, Charles A. Engh, Jr., Joseph Moskal, Mark Pagnano, Michael Swank, Jose F. Guzman
  • COMBINATIONS OF NMDAR MODULATING COMPOUNDS
    Publication number: 20170072005
    Abstract: This disclosure features combinations of NMDAR modulating compounds. This disclosure features combinations that include one or more NMDAR antagonists and GLYX-13 (each of which is sometimes referred to herein as a ‘component”). The beneficial effects of the combination are based, in part, on the finding that administration of GLYX-13 (e.g., a single dose) can reverse and/or prevent NMDAR antagonist-induced cognitive impairment (e.g., NMDAR antagonist-induced impairment in novel object recognition; e.g., induced through repeated dosing of the NMDAR antagonist).
    Type: Application
    Filed: May 6, 2015
    Publication date: March 16, 2017
    Inventor: Joseph MOSKAL
  • NMDA Receptor Modulators and Uses Thereof
    Publication number: 20160368947
    Abstract: Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorders, such as learning, cognitive activities, and analgesia, particularly in alleviating and/or reducing neuropathic pain. Orally available formulations and other pharmaceutically acceptable delivery forms of the compounds, including intravenous formulations, are also disclosed.
    Type: Application
    Filed: August 30, 2016
    Publication date: December 22, 2016
    Inventors: Joseph Moskal, M. A. Khan
  • NMDA receptor modulators and uses thereof
    Patent number: 9512133
    Abstract: Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorder such as learning, cognitive activities, and analgesia, particularly in alleviating and/or reducing neuropathic pain. Orally available formulations and other pharmaceutically acceptable delivery forms of the compounds, including intravenous formulations, are also disclosed.
    Type: Grant
    Filed: October 10, 2013
    Date of Patent: December 6, 2016
    Assignee: Northwestern University
    Inventors: M. Amin Khan, Joseph Moskal, Paul Wood
  • METHODS OF TREATING BRAIN DISORDERS OR IDENTIFYING BIOMARKERS RELATED THERETO
    Publication number: 20160345855
    Abstract: The present disclosure relates in part to methods of treating cognitive disorders and/or identifying biomarkers.
    Type: Application
    Filed: December 15, 2014
    Publication date: December 1, 2016
    Inventor: Joseph Moskal
  • Methods of treating depression and other related diseases
    Patent number: 9340576
    Abstract: The invention relates to methods for treating depression, anxiety, and other related diseases by administering a peptide NMDAR partial agonist.
    Type: Grant
    Filed: June 4, 2013
    Date of Patent: May 17, 2016
    Assignee: Northwestern University
    Inventor: Joseph Moskal
  • Customized patient-specific bone cutting blocks
    Patent number: 9314251
    Abstract: A number of orthopaedic surgical instruments are disclosed. A method, apparatus, and system for fabricating such instruments are also disclosed.
    Type: Grant
    Filed: March 17, 2015
    Date of Patent: April 19, 2016
    Assignee: DEPUY SYNTHES PRODUCTS, INC.
    Inventors: Luke J. Aram, William Bugbee, Charles A. Engh, Joseph Moskal, Mark Pagnano, Michael Swank, Bryan Rose, Mark B. Lester, Jeffrey Roose
  • Methods of treating depression and other related diseases
    Patent number: 9198948
    Abstract: The invention relates to methods for treating depression, anxiety, and other related diseases by administering a peptide NMDAR partial agonist.
    Type: Grant
    Filed: July 9, 2013
    Date of Patent: December 1, 2015
    Assignee: Northwestern University
    Inventor: Joseph Moskal
  • Customized patient-specific tibial cutting blocks
    Patent number: 9173662
    Abstract: A customized patient-specific tibial cutting block comprising a body having a bone-facing surface that has a customized patient-specific negative contour configured to receive (i) a portion of an anterior side of a patient's tibia that has a corresponding positive contour, and (ii) a portion of a medial side of the patient's tibia that has a corresponding positive contour such that, when viewed superiorly, an angle greater than zero is defined between a vertically-extending, bisecting plane of the body and a bisecting sagittal plane of the patient's tibia when the portions of the patient's tibia are received in the customized patient-specific negative contour of the body, and at least one tab extending posteriorly from the body, the at least one tab having a bone-facing surface having a customized patient-specific negative contour configured to receive a portion of the proximal side of the patient's tibia that has a corresponding positive contour.
    Type: Grant
    Filed: February 23, 2011
    Date of Patent: November 3, 2015
    Assignee: DePuy Synthes Products, Inc.
    Inventors: Luke J. Aram, William Bugbee, Charles A. Engh, Jr., Joseph Moskal, Mark W. Pagnano, Michael Swank, Bryan Rose
  • Methods of treating depression and other related diseases
    Patent number: 9149501
    Abstract: The invention relates to methods for treating depression, anxiety, and other related diseases by administering a peptide NMDAR partial agonist.
    Type: Grant
    Filed: July 9, 2013
    Date of Patent: October 6, 2015
    Assignee: Northwestern University
    Inventor: Joseph Moskal
  • Customized patient-specific tibial cutting blocks
    Patent number: 9138239
    Abstract: A number of orthopaedic surgical instruments are disclosed. A method, apparatus, and system for fabricating such instruments are also disclosed.
    Type: Grant
    Filed: February 23, 2011
    Date of Patent: September 22, 2015
    Assignee: DEPUY SYNTHES PRODUCTS, INC.
    Inventors: Luke J. Aram, William Bugbee, Charles A. Engh, Jr., Joseph Moskal, Mark W. Pagnano, Michael Swank
  • Secondary structure stabilized NMDA receptor modulators and uses thereof
    Patent number: 9101612
    Abstract: Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorders such as learning, cognitive activities, and analgesia, particularly in alleviating and/or reducing neuropathic pain.
    Type: Grant
    Filed: February 11, 2011
    Date of Patent: August 11, 2015
    Assignee: Northwestern University
    Inventors: Joseph Moskal, M. Amin Khan
  • Customized Patient-Specific Bone Cutting Blocks
    Publication number: 20150190145
    Abstract: A number of orthopaedic surgical instruments are disclosed. A method, apparatus, and system for fabricating such instruments are also disclosed.
    Type: Application
    Filed: March 17, 2015
    Publication date: July 9, 2015
    Inventors: Luke J. ARAM, William BUGBEE, Charles A. ENGH, Joseph MOSKAL, Mark PAGANO, Michael SWANK, Bryan ROSE, Mark B. LESTER, Jeffrey ROOSE
  • NMDA Receptor Modulators and Uses Thereof
    Publication number: 20150105364
    Abstract: Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorder such as learning, cognitive activities, and analgesia, particularly in alleviating and/or reducing neuropathic pain. Orally available formulations and other pharmaceutically acceptable delivery forms of the compounds, including intravenous formulations, are also disclosed.
    Type: Application
    Filed: October 10, 2013
    Publication date: April 16, 2015
    Applicant: Northwestern University
    Inventors: M. Amin Khan, Joseph Moskal, Paul Wood
  • Customized patient-specific bone cutting blocks
    Patent number: 8979855
    Abstract: A number of orthopaedic surgical instruments are disclosed. A method, apparatus, and system for fabricating such instruments are also disclosed.
    Type: Grant
    Filed: February 23, 2011
    Date of Patent: March 17, 2015
    Assignee: DePuy Synthes Products, Inc.
    Inventors: Luke J. Aram, William Bugbee, Charles A. Engh, Jr., Joseph Moskal, Mark Pagnano, Michael Swank, Bryan Rose, Mark B. Lester, Jeffrey Roose
  • NMDA RECEPTOR MODULATORS AND USES THEREOF
    Publication number: 20150051262
    Abstract: Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorders, such as learning, cognitive activities, and analgesia, particularly in alleviating and/or reducing neuropathic pain. Orally available formulations and other pharmaceutically acceptable delivery forms of the compounds, including intravenous formulations, are also disclosed.
    Type: Application
    Filed: October 24, 2012
    Publication date: February 19, 2015
    Applicant: NORTHWESTERN UNIVERSITY
    Inventors: M. Amin Khan, Joseph Moskal