Patents by Inventor Joseph P. Culver
Joseph P. Culver has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230388478Abstract: A goggle system is provided. The goggle system includes a computing device, a goggle device configured to be worn by a user and including a detector configured to simultaneously acquire image data of a subject in a first image mode and a second image mode, at least one eye assembly configured to display at least one of an image in the first image mode, an image in the second image mode, and a hybrid image including pixels of image data from the first image mode and pixels of image data from the second image mode, and a communications module configured to transmit acquired image data from the goggle device to the computing device.Type: ApplicationFiled: August 11, 2023Publication date: November 30, 2023Inventors: Samuel ACHILEFU, Yang LIU, Viktor GRUEV, Joseph P. CULVER, Walter AKERS, Adam BAUER
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Patent number: 11765340Abstract: A goggle system is provided. The goggle system includes a computing device, a goggle device configured to be worn by a user and including a detector configured to simultaneously acquire image data of a subject in a first image mode and a second image mode, at least one eye assembly configured to display at least one of an image in the first image mode, an image in the second image mode, and a hybrid image including pixels of image data from the first image mode and pixels of image data from the second image mode, and a communications module configured to transmit acquired image data from the goggle device to the computing device.Type: GrantFiled: March 8, 2022Date of Patent: September 19, 2023Assignee: WASHINGTON UNIVERSITYInventors: Samuel Achilefu, Yang Liu, Viktor Gruev, Joseph P. Culver, Walter Akers, Adam Bauer
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Publication number: 20220201274Abstract: A goggle system is provided. The goggle system includes a computing device, a goggle device configured to be worn by a user and including a detector configured to simultaneously acquire image data of a subject in a first image mode and a second image mode, at least one eye assembly configured to display at least one of an image in the first image mode, an image in the second image mode, and a hybrid image including pixels of image data from the first image mode and pixels of image data from the second image mode, and a communications module configured to transmit acquired image data from the goggle device to the computing device.Type: ApplicationFiled: March 8, 2022Publication date: June 23, 2022Inventors: Samuel ACHILEFU, Yang LIU, Viktor GRUEV, Joseph P. CULVER, Walter AKERS, Adam BAUER
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Patent number: 11310485Abstract: A goggle system is provided. The goggle system includes a computing device, a goggle device configured to be worn by a user and including a detector configured to simultaneously acquire image data of a subject in a first image mode and a second image mode, at least one eye assembly configured to display at least one of an image in the first image mode, an image in the second image mode, and a hybrid image including pixels of image data from the first image mode and pixels of image data from the second image mode, and a communications module configured to transmit acquired image data from the goggle device to the computing device.Type: GrantFiled: December 15, 2020Date of Patent: April 19, 2022Assignee: WASHINGTON UNIVERSITYInventors: Samuel Achilefu, Yang Liu, Viktor Gruev, Joseph P. Culver, Walter Akers, Adam Bauer
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Publication number: 20210105455Abstract: A goggle system is provided. The goggle system includes a computing device, a goggle device configured to be worn by a user and including a detector configured to simultaneously acquire image data of a subject in a first image mode and a second image mode, at least one eye assembly configured to display at least one of an image in the first image mode, an image in the second image mode, and a hybrid image including pixels of image data from the first image mode and pixels of image data from the second image mode, and a communications module configured to transmit acquired image data from the goggle device to the computing device.Type: ApplicationFiled: December 15, 2020Publication date: April 8, 2021Inventors: Samuel ACHILEFU, Yang LIU, Viktor GRUEV, Joseph P. CULVER, Walter AKERS, Adam BAUER
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Publication number: 20200375465Abstract: A system includes a wearable head apparatus and an electronic console. The head apparatus is configured to receive resultant light from the head of a subject. The electronic console includes a fiber array, a detector, and a computing device. The fiber array includes a plurality of fibers configured to transport resultant light received by the head apparatus. The detector includes a plurality of super-pixels each defined by a plurality of pixels of an array of pixels. Each super-pixel is associated with a fiber. Each super-pixel is configured to generate a plurality of detection signals in response to detected resultant light from its associated fiber. The computing device receives the detection signals from each of the plurality of super-pixels. The computing device generates a high density-diffuse optical tomography (HD-DOT) image signal of the brain activity of the subject based on the detection signals from the super-pixels.Type: ApplicationFiled: August 19, 2020Publication date: December 3, 2020Inventors: Joseph P. Culver, Karla Bergonzi, Adam Eggebrecht, Silvina Ferradal
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Patent number: 10786156Abstract: A system includes a wearable head apparatus and an electronic console. The head apparatus is configured to receive resultant light from the head of a subject. The electronic console includes a fiber array, a detector, and a computing device. The fiber array includes a plurality of fibers configured to transport resultant light received by the head apparatus. The detector includes a plurality of super-pixels each defined by a plurality of pixels of an array of pixels. Each super-pixel is associated with a fiber. Each super-pixel is configured to generate a plurality of detection signals in response to detected resultant light from its associated fiber. The computing device receives the detection signals from each of the plurality of super-pixels. The computing device generates a high density-diffuse optical tomography (HD-DOT) image signal of the brain activity of the subject based on the detection signals from the super-pixels.Type: GrantFiled: October 16, 2015Date of Patent: September 29, 2020Assignee: Washington UniversityInventors: Joseph P. Culver, Karla Bergonzi, Adam Eggebrecht, Silvina Ferradal
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Publication number: 20190104300Abstract: A compound of formula (I) is provided having the structure: cypate-cyclo(Cys-Gly-Arg-Asp-Ser-Pro-Cys)-Lys-OH, and each amino acid is independently in a D or L configuration. Also provided are pharmaceutical compositions that include the compound of formula (I) and its use in treating cancer by administering it to a patient in need thereof.Type: ApplicationFiled: November 13, 2018Publication date: April 4, 2019Inventors: Samuel Achilefu, Yang Liu, Viktor Gruev, Joseph P. Culver, Walter Akers, Adam Bauer
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Patent number: 10230943Abstract: A goggle system is provided. The goggle system includes a computing device, a goggle device configured to be worn by a user and including a detector configured to simultaneously acquire image data of a subject in a first image mode and a second image mode, at least one eye assembly configured to display at least one of an image in the first image mode, an image in the second image mode, and a hybrid image including pixels of image data from the first image mode and pixels of image data from the second image mode, and a communications module configured to transmit acquired image data from the goggle device to the computing device.Type: GrantFiled: January 23, 2013Date of Patent: March 12, 2019Assignee: Washington UniversityInventors: Samuel Achilefu, Yang Liu, Viktor Gruev, Joseph P. Culver, Walter Akers, Adam Bauer
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Publication number: 20190075289Abstract: A goggle system is provided. The goggle system includes a computing device, a goggle device configured to be worn by a user and including a detector configured to simultaneously acquire image data of a subject in a first image mode and a second image mode, at least one eye assembly configured to display at least one of an image in the first image mode, an image in the second image mode, and a hybrid image including pixels of image data from the first image mode and pixels of image data from the second image mode, and a communications module configured to transmit acquired image data from the goggle device to the computing device.Type: ApplicationFiled: October 24, 2018Publication date: March 7, 2019Inventors: Samuel Achilefu, Yang Liu, Viktor Gruev, Joseph P. Culver, Walter Akers, Adam Bauer
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Publication number: 20170231501Abstract: A system includes a wearable head apparatus and an electronic console. The head apparatus is configured to receive resultant light from the head of a subject. The electronic console includes a fiber array, a detector, and a computing device. The fiber array includes a plurality of fibers configured to transport resultant light received by the head apparatus. The detector includes a plurality of super-pixels each defined by a plurality of pixels of an array of pixels. Each super-pixel is associated with a fiber. Each super-pixel is configured to generate a plurality of detection signals in response to detected resultant light from its associated fiber. The computing device receives the detection signals from each of the plurality of super-pixels. The computing device generates a high density-diffuse optical tomography (HD-DOT) image signal of the brain activity of the subject based on the detection signals from the super-pixels.Type: ApplicationFiled: October 16, 2015Publication date: August 17, 2017Inventors: Joseph P. Culver, Karla Bergonzi, Adam Eggebrecht, Silvina Ferradal
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Publication number: 20170014066Abstract: A method for utilizing an optical system for taskless mapping of brain function includes determining a time series of dynamic light measurements for a plurality of spatially distributed source-detector pairs, receiving the dynamic light measurements over a period of time using the source-detector pairs without dependence on either a task or a change in physiological condition, generating a plurality of temporal correlations between regions of a brain for the light measurements based on the time series of the spatially distributed source-detector pairs and the received dynamic light measurements, producing at least one map of a respective strength of each of a plurality of temporal correlations, producing overlapping source-detector pairs measurements using diffuse optical tomography (DOT) geometries, reconstructing data representative of the dynamic light measurements into an image space using at least one DOT algorithm, and co-registering DOT voxel images obtained by the reconstruction to anatomical informatType: ApplicationFiled: September 30, 2016Publication date: January 19, 2017Inventors: Joseph P. Culver, Brian R. White, Bradley L. Schlaggar, Abraham Z. Snyder, Marcus E. Raichle, Michael D. Fox, Justin L. Vincent
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Patent number: 9480425Abstract: A method for utilizing an optical system for mapping brain function includes determining a time series of light intensity measurements for spatially distributed source and detector pairs, receiving light measurements over a period of time, and producing at least one map of a respective strength of each of a plurality of temporal correlations, wherein the temporal correlations are based on the time series of the spatially distributed source and detector pairs and the light measurements.Type: GrantFiled: April 17, 2009Date of Patent: November 1, 2016Assignee: WASHINGTON UNIVERSITYInventors: Joseph P. Culver, Brian R. White, Bradley L. Schlaggar, Abraham Z. Snyder, Marcus E. Raichle, Michael D. Fox, Justin L. Vincent
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Publication number: 20140340287Abstract: A goggle system is provided. The goggle system includes a computing device, a goggle device configured to be worn by a user and including a detector configured to simultaneously acquire image data of a subject in a first image mode and a second image mode, at least one eye assembly configured to display at least one of an image in the first image mode, an image in the second image mode, and a hybrid image including pixels of image data from the first image mode and pixels of image data from the second image mode, and a communications module configured to transmit acquired image data from the goggle device to the computing device.Type: ApplicationFiled: January 23, 2013Publication date: November 20, 2014Inventors: Samuel Achilefu, Yang Liu, Viktor Gruev, Joseph P. Culver, Walter Akers, Adam Bauer
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Publication number: 20090292210Abstract: A method for utilizing an optical system for mapping brain function includes determining a time series of light intensity measurements for spatially distributed source and detector pairs, receiving light measurements over a period of time, and producing at least one map of a respective strength of each of a plurality of temporal correlations, wherein the temporal correlations are based on the time series of the spatially distributed source and detector pairs and the light measurements.Type: ApplicationFiled: April 17, 2009Publication date: November 26, 2009Applicant: WASHINGTON UNIVERSITY IN ST. LOUISInventors: Joseph P. Culver, Brian R. White, Bradley L. Schlaggar, Abraham Z. Snyder, Marcus E. Raichle, Michael D. Fox, Justin L. Vincent
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Patent number: 6487428Abstract: Extravasation of a fluid applied to a patient is determined by monitoring light transmitted through the tissue of the patient in proximity to a site at which the fluid is being injected. Light is radiated from a plurality of light sources in an encoded manner into the body part at the site at which the fluid is injected and the light that is reflected, scattered, diffused or otherwise emitted from the body part is detected individually by a plurality of light detectors. Signals representative of the detected light are developed and, prior to injection of the fluid, references are developed against which measurements made during injection of the fluid are compared. New light signals having an improved signal-to-noise ratio are developed from the comparisons of the detected light signals with the associated reference signals.Type: GrantFiled: August 31, 2000Date of Patent: November 26, 2002Assignee: Trustees of The University of PennsylvaniaInventors: Joseph P. Culver, Arjun G. Yodh