Patents by Inventor Joseph P. Loeffler
Joseph P. Loeffler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7195011Abstract: A feed system for an aerosolizer utilizes an ampoule containing a liquid and includes a housing having an ampoule region into which the ampoule is held, and a liquid receiving region that is adapted to receive liquid dispensed from the ampoule. An interface is used to couple the liquid receiving region to an aerosol generator, whereby liquid from the liquid receiving region is permitted to flow to the aerosol generator for aerosolization.Type: GrantFiled: June 30, 2004Date of Patent: March 27, 2007Assignee: Aerogen, Inc.Inventors: Joseph P. Loeffler, David Rapp, Victor Briones, Ralf Bitdinger, Michael Klimowicz
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Patent number: 7100600Abstract: A fluid filled ampoule comprises an ampoule body having a top end, a bottom end and a sealed interior containing a liquid. A top tab is coupled to the top end and is removable to create a drain vent in the top end. A bottom tab is coupled to the bottom end and is removable to create a drain opening in the bottom end. A movable shroud is coupled to the top end and is disposed about the top tab. The shroud is movable to permit access to the top tab.Type: GrantFiled: March 20, 2001Date of Patent: September 5, 2006Assignee: Aerogen, Inc.Inventors: Joseph P. Loeffler, Richard Q. Poynter, David Rapp, Michael Klimowicz
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Patent number: 7032590Abstract: A fluid filled ampoule comprises an ampoule body having a top end, a bottom end and a sealed interior containing a liquid. A top tab is coupled to the top end and is removable to create a drain vent in the top end. A bottom tab is coupled to the bottom end and is removable to create a drain opening in the bottom end. A movable shroud is coupled to the top end and is disposed about the top tab. The shroud is movable to permit access to the top tab.Type: GrantFiled: January 5, 2004Date of Patent: April 25, 2006Assignee: Aerogen, Inc.Inventors: Joseph P. Loeffler, Richard Q. Poynter, David Rapp, Michael Klimowicz
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Patent number: 6948491Abstract: A feed system for an aerosolizer utilizes an ampoule containing a liquid and includes a housing having an ampoule region into which the ampoule is held, and a liquid receiving region that is adapted to receive liquid dispensed from the ampoule. An interface is used to couple the liquid receiving region to an aerosol generator, whereby liquid from the liquid receiving region is permitted to flow to the aerosol generator for aerosolization.Type: GrantFiled: March 20, 2001Date of Patent: September 27, 2005Assignee: Aerogen, Inc.Inventors: Joseph P. Loeffler, David Rapp, Victor Briones, Ralf Bitdinger, Michael Klimowicz
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Publication number: 20040256488Abstract: A feed system for an aerosolizer utilizes an ampoule containing a liquid and includes a housing having an ampoule region into which the ampoule is held, and a liquid receiving region that is adapted to receive liquid dispensed from the ampoule. An interface is used to couple the liquid receiving region to an aerosol generator, whereby liquid from the liquid receiving region is permitted to flow to the aerosol generator for aerosolization.Type: ApplicationFiled: June 30, 2004Publication date: December 23, 2004Applicant: Aerogen, Inc.Inventors: Joseph P. Loeffler, David Rapp, Victor Briones, Ralf Bitdinger, Michael Klimowicz
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Publication number: 20040139968Abstract: A fluid filled ampoule comprises an ampoule body having a top end, a bottom end and a sealed interior containing a liquid. A top tab is coupled to the top end and is removable to create a drain vent in the top end. A bottom tab is coupled to the bottom end and is removable to create a drain opening in the bottom end. A movable shroud is coupled to the top end and is disposed about the top tab. The shroud is movable to permit access to the top tab.Type: ApplicationFiled: January 5, 2004Publication date: July 22, 2004Applicant: Aerogen, Inc.Inventors: Joseph P. Loeffler, Richard Q. Poynter, David Rapp, Michael Klimowicz
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Publication number: 20020134374Abstract: A fluid filled ampoule comprises an ampoule body having a top end, a bottom end and a sealed interior containing a liquid. A top tab is coupled to the top end and is removable to create a drain vent in the top end. A bottom tab is coupled to the bottom end and is removable to create a drain opening in the bottom end. A movable shroud is coupled to the top end and is disposed about the top tab. The shroud is movable to permit access to the top tab.Type: ApplicationFiled: June 7, 2001Publication date: September 26, 2002Inventors: Joseph P. Loeffler, Richard Q. Poynter, David Rapp, Michael Klimowicz
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Publication number: 20020134377Abstract: A fluid filled ampoule comprises an ampoule body having a top end, a bottom end and a sealed interior containing a liquid. A top tab is coupled to the top end and is removable to create a drain vent in the top end. A bottom tab is coupled to the bottom end and is removable to create a drain opening in the bottom end. A movable shroud is coupled to the top end and is disposed about the top tab. The shroud is movable to permit access to the top tab.Type: ApplicationFiled: March 20, 2001Publication date: September 26, 2002Inventors: Joseph P. Loeffler, Richard Q. Poynter, David Rapp, Michael Klimowicz
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Publication number: 20020134372Abstract: A feed system for an aerosolizer utilizes an ampoule containing a liquid and includes a housing having an ampoule region into which the ampoule is held, and a liquid receiving region that is adapted to receive liquid dispensed from the ampoule. An interface is used to couple the liquid receiving region to an aerosol generator, whereby liquid from the liquid receiving region is permitted to flow to the aerosol generator for aerosolization.Type: ApplicationFiled: March 20, 2001Publication date: September 26, 2002Inventors: Joseph P. Loeffler, David Rapp, Victor Briones, Ralf Bitdinger, Michael Klimowicz
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Publication number: 20020134375Abstract: A fluid filled ampoule comprises an ampoule body having a top end, a bottom end and a sealed interior containing a liquid. A top tab is coupled to the top end and is removable to create a drain vent in the top end. A bottom tab is coupled to the bottom end and is removable to create a drain opening in the bottom end. A movable shroud is coupled to the top end and is disposed about the top tab. The shroud is movable to permit access to the top tab.Type: ApplicationFiled: June 7, 2001Publication date: September 26, 2002Inventors: Joseph P. Loeffler, Richard Q. Poynter, David Rapp, Michael Klimowicz
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Patent number: 6159140Abstract: A radiation delivery catheter which increases the margin of safety and reduces unintended exposure to radiation dosage during delivery thereof to a target area to reduce the likelihood of the development of restenosis. The catheter includes a shaft comprised of radiation shielding material, to shield the patient and staff from unintended radiation exposure. The catheter further includes a treatment section including a reservoir balloon comprised of radiation trans-parent material, which enables predetermined concentrations of radioactivity in the radiation source to permeate therethrough into the target area in a substantially uniform dosage pattern.Type: GrantFiled: February 17, 1998Date of Patent: December 12, 2000Assignee: Advanced Cardiovascular SystemsInventors: Joseph P. Loeffler, Eric D. Peterson, Jon A. Becker
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Patent number: 5897911Abstract: The thickness of a polymer coating applied to the interior surface of a stent is precisely controlled by fitting a mandrel within its interior. Fitment of an exterior mold serves to additionally control the thickness of polymer on the exterior surface of the stent. Alternatively, a preformed sheath of polymer is fitted to the interior of the stent whereby the subsequent application of polymer not only causes the exterior to become coated but also causes the sheath to become adhered to the stent.Type: GrantFiled: August 11, 1997Date of Patent: April 27, 1999Assignee: Advanced Cardiovascular Systems, Inc.Inventor: Joseph P. Loeffler
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Patent number: 5891154Abstract: A stent delivery method and system are disclosed. The system generally includes an elongated delivery sheath and a perfusion catheter disposed within a sheath lumen of the sheath having an expandable member on its distal extremity. The sheath includes perfusion ports to maintain blood flow to perfusion ports in the catheter during delivery of the stent. A manipulating device is provided at the proximal end of the delivery system to effect relative axial movement between the sheath and the catheter so as to expose the stent mounted on the expandable member on the catheter within a body lumen such as a coronary artery and allow the expansion of the stent by the expansion of the expandable member.Type: GrantFiled: May 6, 1997Date of Patent: April 6, 1999Assignee: Advanced Cardiovascular System, Inc.Inventor: Joseph P. Loeffler
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Patent number: 5700286Abstract: The drug loaded stent includes an expandable stent structural member, and a planar sheet of polymeric material attached to the outside of the expandable stent structural member. The polymeric material is preferably bioabsorbable, and loaded or coated with a therapeutic agent or drug to reduce or prevent restenosis in the vessel being treated. The polymer material can be attached to the metal stent at one or more points, and wrapped in a coil around the stent in an unexpanded state, to uncoil and expand in diameter to substantially match the expanded diameter of the metal stent; or can be wrapped tightly around the stent structural member and attached to itself, to stretch radially when the stent structural member is expanded. In another currently preferred embodiment, a combination of a stent structural member and a polymeric film wrapping can be provided with a coating of lubricious material.Type: GrantFiled: August 22, 1996Date of Patent: December 23, 1997Assignee: Advanced Cardiovascular Systems, Inc.Inventors: Joseph M. Tartaglia, Joseph P. Loeffler, Todd H. Turnlund
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Patent number: 5637113Abstract: The drug loaded stent includes an expandable stent structural member, and a planar sheet of polymeric material attached to the outside of the expandable stent structural member. The polymeric material is preferably bioabsorbable, and loaded or coated with a therapeutic agent or drug to reduce or prevent restenosis in the vessel being treated. The polymer material can be attached to the metal stent at one or more points, and wrapped in a coil around the stent in an unexpanded state, to uncoil and expand in diameter to substantially match the expanded diameter of the metal stent; or can be wrapped tightly around the stent structural member and attached to itself, to stretch radially when the stent structural member is expanded. In another currently preferred embodiment, a combination of a stent structural member and a polymeric film wrapping can be provided with a coating of lubricious material.Type: GrantFiled: December 13, 1994Date of Patent: June 10, 1997Assignee: Advanced Cardiovascular Systems, Inc.Inventors: Joseph M. Tartaglia, Joseph P. Loeffler, Todd H. Turnlund